Results 61 to 70 of about 657,350 (312)

Molecular classification of hepatocellular adenomas: impact on clinical practice

Hepatic Oncology, 2018
Hepatocellular adenomas are rare benign liver tumors usually developing in young women using oral contraception. The two main complications are hemorrhage (10–20%) and malignant transformation into hepatocellular carcinoma (
Anne-Laure Védie, Olivier Sutter, Marianne Ziol, Jean-Charles Nault   +3 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

The pressure field model: a challenge to the conventional Starling and Guyton model of hemodynamic management

Frontiers in Anesthesiology
IntroductionEnsuring hemodynamic stability with adequate perfusion to vital organs is critical to the safe conduct of anesthesia. Recent advances in hemodynamic monitoring technologies allow pressure, flow, and resistance to be measured continuously ...
Stephen F. Woodford, Stephen F. Woodford, Laurence Weinberg, Laurence Weinberg, Lachlan F. Miles, Lachlan F. Miles, Ruth C. Marshall, Bernhard Riedel, Bernhard Riedel, Philip J. Peyton, Philip J. Peyton   +10 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Treatment Patterns of Cancer-associated Thrombosis in the Netherlands: The Four Cities Study

TH Open
Background Current guidelines recommend either low-molecular weight heparin (LMWH) or direct oral anticoagulants (DOACs) as first-line treatment in cancer-associated venous thromboembolism (VTE).
Fleur H.J. Kaptein, Noori A.M. Guman, Susan B. Lohle, Frederikus A. Klok, Albert T.A. Mairuhu, Pieter W. Kamphuisen, Nick Van Es, Menno V. Huisman   +7 more
doaj   +1 more source

Obesity and the risk of intracerebral hemorrhage: the multicenter study on cerebral hemorrhage in Italy.

, 2013
BACKGROUND AND PURPOSE: The effect of obesity on the risk of intracerebral hemorrhage (ICH) may depend on the pathophysiology of vessel damage. To further address this issue, we investigated and quantified the correlations between obesity and obesity-
Poli, L, Ciccone, A, Volonghi I, CASO, Valeria, Caso, V, Grassi M, Giossi A, IACOVIELLO, LICIA, Pezzini A, GRASSI, MARIO, Agnelli G, Di Castelnuovo A, PEZZINI, Alessandro, NICHELLI, Paolo Frigio, Zini, A, Lanari, A, Simone AM, LANARI, Alessia, Gamba, M, Guido, D, ZINI, Andrea, Falzone F, Nichelli, Pf, Pentore R, Padovani A, on behalf of the Multicentre Study on Cerebral Hemorrhage in Italy Investigators, Nichelli PF, Iacoviello L, Agnelli, G, Colombi M, Volonghi, I, Ritelli, M, PACIARONI, Maurizio, Silvestrelli, G, PADOVANI, Alessandro, Costa, P, De Gaetano, G, AGNELLI, Giancarlo, Gamba M, Iacoviello, L, Del Zotto, E, Grassi, M, Ritelli M, Poli L, Del Zotto E, Paciaroni M, Multicentre Study on Cerebral Hemorrhage in Italy Investigators, Morotti, A, Simone, Am, Di Castelnuovo, A, Zini A, Padovani A., COLOMBI, Marina, Morotti A, Ciccone A, Pentore, R, Silvestrelli G, Caso V, Costa P, Guido D, Paciaroni, M, SILVESTRELLI, Giorgio, Falzone, F, De Gaetano G, Lanari A, Giossi, A   +65 more
core   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes, Leonardo Cruz‐Criollo, Eric Kontowicz, Marta Olivé‐Gadea, Francesco Diana, Johannes Kaesmacher, Adnan Mujanovic, Serdar Geyik, Songul Senadim, Amedeo Cervo, Andrea Salcuni, Mariangela Piano, Manuel Moreu, Alfonso López‐Frías, Ameer E. Hassan, Samantha Miller, Elena Zapata‐Arriaza, Asier de Albóniga‐Chindurza, Mauro Bergui, Stefano Molinaro, João André Sousa, Fábio Gomes, João Sargento‐Freitas, Andrea Alexandre, Alessandro Pedicelli, Jeremy Hofmeister, Paolo Machi, Luca Scarcia, Erwah Kalsoum, Jose Amorim, Torcato Meira, Leonardo Renieri, Francesco Capasso, Daniele Romano, Eduardo Bárcena‐Ruiz, David Seoane, Mohamad Abdalkader, Piers Klein, Thanh N. Nguyen, Catarina Perry da Câmara, Anderson Brito, Nashwa Abdelhakim, Isabel Fragata, Dileep R. Yavagal, Jude H. Charles, Jose Rodriguez Castro, Pedro Vega, Atilla Özcan Özdemir, Zehra Uysal Kocabaş, Stanislas Smajda, Sadiq Al Salman, Jane Khalife, Tudor G. Jovin, Francesco Biraschi, Francesca Richetti, Pedro Castro, Luis Albuquerque, Adnan Siddiqui, Vinay Jaikumar, Pedro Navia, Nikolaos Ntoulias, Marios Psychogios, Mariano Velo, Joaquín Zamarro, Gonzalo de Paco, Yazan Ashouri, Mohammad AlMajali, Juan F. Arenillas, Alicia Sierra, Michele Romoli, João Pedro Marto, Shadi Yaghi, Marc Ribo, Alejandro Tomasello, Manuel Requena, Santiago Ortega‐Gutierrez   +75 more
wiley   +1 more source

The risk of venous thromboembolism in primary central nervous system lymphoma: a systematic review and meta-analysis

Research and Practice in Thrombosis and Haemostasis
Primary central nervous system lymphoma (PCNSL) is a rare extranodal lymphoma localized to the central nervous system. Small single-center studies have suggested that patients with PCNSL may be at high risk of venous thromboembolism (VTE).
Adam Suleman, Rachel Wine, Marc Carrier, Lisa K. Hicks   +3 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Successful transarterial embolization of hemorrhage following percutaneous liver biopsy in hepatic amyloidosis

Clinical Case Reports
Key Clinical Message Percutaneous liver biopsy is essential for diagnosing hepatic amyloidosis. Post biopsy hemorrhage is unusual but can occur. The potential for bleeding can result from various factors, such as the deposition of amyloid in the hepatic ...
Sasikorn Feinggumloon, Tanapong Panpikoon, Thanakrit Piyajaroenkij, Tanatip Prasertchai, Tharintorn Treesit   +4 more
doaj   +1 more source