Results 81 to 90 of about 3,315,392 (318)

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

Advanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui, Xinhang Meng, Yujie Luo, Jinfeng Qian, Fengrun Sun, Mingke Qiu, Songcun Wang   +6 more
wiley   +1 more source

Periprocedural hemostatic prophylaxis and outcomes in bleeding disorder of unknown cause

Research and Practice in Thrombosis and Haemostasis
Background: Bleeding disorder of unknown cause (BDUC) is a diagnostic category encompassing patients with a clear bleeding phenotype but without identifiable abnormality on hemostatic testing.
Callie Berkowitz, Alice Ma, Vanessa Miller, Supreet Goraya, Kristi Kirkland, Julie Grabell, Nigel S. Key, Paula D. James   +7 more
doaj  

Prophylactic radiologic interventions to reduce postpartum hemorrhage in women with risk factors for placenta accreta spectrum disorder: a nationwide cohort study [PDF]

, 2023
Lisanne R. Bonsen, Valerie Harskamp, Sana Feddouli, Kitty W.M. Bloemenkamp, Johannes J. Duvekot, Aad Pors, Jos van Roosmalen, Joost J. Zwart, J. M. M. van Lith, Joris Hendriks, Thijs Urlings, Thomas van den Akker, Johanna G. van der Bom, Dacia D. C. A. Henriquez   +13 more
openalex   +1 more source

Thrombotic and hemorrhagic complications in chronic myeloproliferative disorders

Biomedicine & Pharmacotherapy, 1996
Bleeding and thrombosis are major causes of morbidity and mortality in patients with chronic myeloproliferative disorders. We retrospectively evaluated 101 consecutive patients affected by primary thrombocytosis (46 male, 55 female, aged 18-84 years; mean +/- SD 61 +/- 15) followed for a period ranging from 6 months up to 10 years (median 5 years) at ...
Sagripanti A, Ferretti A, NICOLINI, ANDREA, CARPI, ANGELO   +3 more
openaire   +4 more sources

Cytokine Storm Induction Linked to Multi‐Organ Failure in Fatal Jellyfish Stings

Advanced Science, EarlyView.
N. nomurai is the most important injurious species in the coastal area of China. Model construction, omics analysis, mechanism exploration, and intervention measures of N. nomurai envenomation are performed in the current study, and it suggested that cytokine storm played an important role in pathogenesis.
Yichao Wang, Yi Wang, Fengling Yang, Jingbo Chen, Xiaoyu Geng, Qing Sun, Jinyu Zhang, Chang Liu, Jie Lv, Xiaochuan Hou, Yongfang Wang, Huiyan Lin, Jing Zhang, Lingxin Chen, Bing Yan, Liang Xiao   +15 more
wiley   +1 more source

Management of heavy menstrual bleeding in a multidisciplinary young women’s clinic: a Dutch experience

Research and Practice in Thrombosis and Haemostasis
Background: Heavy menstrual bleeding (HMB) is common in young women. It may lead to iron deficiency with or without anemia, decreased school, work, sport, and social participation, and may be the first sign of underlying bleeding disorders (BDs ...
Yara Dixon, Bart Kabboord, Carla Groenestein-Sondaal, Marieke J.H.A. Kruip, Carolien van der Velden, Greta Mulders, C. Heleen van Ommen   +6 more
doaj  

Correspondence: Guillain-Barré syndrome and hemorrhagic fever with renal syndrome

BMC Infectious Diseases, 2019
Jiao and colleagues reported a case of hemorrhagic fever with renal syndrome who developed respiratory failure and symmetrical flaccid paralysis of all extremities. Electrophysiology revealed peripheral nerve injuries mainly in axons.
Linpei Jia, Rufu Jia, Hongliang Zhang
doaj   +1 more source

Intracranial hemorrhage in a patient with depressive anxiety disorder about a case [PDF]

, 2023
M. Palomo Monge, M. V. Lopez Rodrigo, C. García Montero, A. Osca Oliver, V. R. Fons, A. Duque Domínguez   +5 more
openalex   +1 more source

PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury

Advanced Science, EarlyView.
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan, Fang Yang, Linlin Hou, Yan Zhang, Xin Pang, Yuqi Du, Hongyi Yan, Huanzhou Zhu, Yue Cheng, Yue Wu, Pinpin Jiang, Mengnan Guo, Mengying Zhang, Jinjie Guo, Huihui Hao, Yong Jiang, Yi Li, Yanxia Gao   +17 more
wiley   +1 more source