Characterization of Monoclonal Antibodies to Junin Virus Nucleocapsid Protein and Application to the Diagnosis of Hemorrhagic Fever Caused by South American Arenaviruses [PDF]
Clinical and Vaccine Immunology, 2009 ABSTRACT Junin virus (JUNV), Machupo virus, Guanarito virus, Sabia virus, and Chapare virus are members of New World arenavirus clade B and are the etiological agents of viral hemorrhagic fevers that occur in South America. In this study, we produced three monoclonal antibodies (MAbs) to the recombinant nucleocapsid protein of JUNV ...
Nakauchi, Mina +7 more
openaire +3 more sources
Wild-type Yellow fever virus in cerebrospinal fluid from fatal cases in Brazil, 2018
Frontiers in Virology, 2022 Yellow fever virus (YFV) is the causative agent of yellow fever (YF), a hemorrhagic and viscerotropic acute disease. Severe YF has been described in approximately 15-25% of YF patients, with 20-50% of severe YF cases being fatal.
Izabela Mauricio de Rezende +19 more
doaj +1 more source
Site 1 Protease Is Required for Proteolytic Processing of the Glycoproteins of the South American Hemorrhagic Fever Viruses Junin, Machupo, and Guanarito [PDF]
Journal of Virology, 2008 ABSTRACT The cellular proprotein convertase s ite 1 p rotease (S1P) has been implicated in the proteolytic processing of the glycoproteins (GPs) of Old World arenaviruses. Here we report that S1P is also involved in the processing of the GPs of the genetically more-distant South ...
Rojek, Jillian M. +4 more
openaire +3 more sources
Complete Genome Sequence of Dengue Virus Serotype 2, Asian/American Genotype, Isolated from the Urine of a Venezuelan Child with Hemorrhagic Fever in 2016 [PDF]
Genome Announcements, 2018 ABSTRACT The complete genome sequence was obtained for a Dengue virus 2 isolate from the urine of an 8-year-old girl who was hospitalized with dengue hemorrhagic fever in 2016 in Venezuela.
Gabriela M. Blohm +7 more
openaire +3 more sources
Retrobulbar Neuritis: Rare Presentation in Dengue Fever
Indian Journal of Medical Specialities, 2019 Dengue fever is transmitted by the bite of infected female Aedes aegypti mosquito. There has been a worldwide resurgence of disease over the past few decades.
Atul Bhasin +4 more
doaj +1 more source
Phylogenetic reconstruction of dengue virus type 2 in Colombia
Virology Journal, 2012 Background Dengue fever is perhaps the most important viral re-emergent disease especially in tropical and sub-tropical countries, affecting about 50 million people around the world yearly.
Méndez Jairo A +6 more
doaj +1 more source
A genetic and pathologic study of a DENV2 clinical isolate capable of inducing encephalitis and hematological disturbances in immunocompetent mice. [PDF]
PLoS ONE, 2012 Dengue virus (DENV) is the causative agent of dengue fever (DF), a mosquito-borne illness endemic to tropical and subtropical regions. There is currently no effective drug or vaccine formulation for the prevention of DF and its more severe forms, i.e ...
Jaime Henrique Amorim +6 more
doaj +1 more source
Neutralizing Antibodies after Infection with Dengue 1 Virus
Emerging Infectious Diseases, 2007 Severity of disease is markedly increased when infection with dengue virus type 2 (DENV-2) follows infection with DENV-1. Studies have shown that heterologous neutralizing antibody titers are inversely correlated with severity of a second infection.
Gustavo Kourí +10 more
doaj +1 more source
Interim Report on SNP analysis and forensic microarray probe design for South American hemorrhagic fever viruses, tick-borne encephalitis virus, henipaviruses, Old World Arenaviruses, filoviruses, Crimean-Congo hemorrhagic fever viruses, Rift Valley fever [PDF]
, 2012 The goal of this project is to develop forensic genotyping assays for select agent viruses, enhancing the current capabilities for the viral bioforensics and law enforcement community. We used a multipronged approach combining bioinformatics analysis, PCR-enriched samples, microarrays and TaqMan assays to develop high resolution and cost effective ...
Jaing, C, Gardner, S
openaire +2 more sources
Clinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source