Results 31 to 40 of about 20,574 (188)

HLA-B*44 Is Associated with Dengue Severity Caused by DENV-3 in a Brazilian Population

open access: yesJournal of Tropical Medicine, 2013
Human leukocyte antigen (HLA) alleles have been correlated with susceptibility or resistance to severe dengue; however, few immunogenetic studies have been performed in Latin American (LA) populations. We have conducted immunogenetic studies of HLA class
Liciana Xavier Eurico de Alencar   +9 more
doaj   +1 more source

Specific genetic markers for detecting subtypes of dengue virus serotype-2 in isolates from the states of Oaxaca and Veracruz, Mexico

open access: yesBMC Microbiology, 2008
Background Dengue (DEN) is an infectious disease caused by the DEN virus (DENV), which belongs to the Flavivirus genus in the family Flaviviridae. It has a (+) sense RNA genome and is mainly transmitted to humans by the vector mosquito Aedes aegypti ...
Camacho-Nuez Minerva   +8 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Flaviviruses including Dengue virus (DENV), Yellow fever virus (YFV), West Nile virus (WNV), and Japanese encephalitis virus (JEV) are global health problems that caused several serious diseases such as fever, hemorrhagic fever, and encephalitis in the ...
Zi-Yang Sheng   +9 more
doaj   +1 more source

Yellow fever transmission in non-human primates, Bahia, Northeastern Brazil.

open access: yesPLoS Neglected Tropical Diseases, 2020
Yellow fever virus (YFV) causes a clinical syndrome of acute hemorrhagic hepatitis. YFV transmission involves non-human primates (NHP), mosquitoes and humans.
Jaqueline Goes de Jesus   +34 more
doaj   +1 more source

Hantaviroses Hantaviruses

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2003
As hantaviroses constituem infecções zoonóticas amplamente distribuídas em todo o mundo. A febre hemorrágica com síndrome renal mostra-se endêmica na Ásia e Europa, acometendo milharea de pessoas anualmente.
Marcelo Simão Ferreira
doaj   +1 more source

Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome. [PDF]

open access: yesPLoS ONE, 2014
In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH.
Soraya S Pereira   +14 more
doaj   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

open access: yesAdvanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun   +6 more
wiley   +1 more source

International external quality assessment study for molecular detection of Lassa virus.

open access: yesPLoS Neglected Tropical Diseases, 2015
Lassa virus (LASV) is a causative agent of hemorrhagic fever in West Africa. In recent years, it has been imported several times to Europe and North America. The method of choice for early detection of LASV in blood is RT-PCR.
Sergejs Nikisins   +5 more
doaj   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu   +6 more
wiley   +1 more source

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