Results 31 to 40 of about 20,484 (175)
BMC Microbiology, 2008 Background Dengue (DEN) is an infectious disease caused by the DEN virus (DENV), which belongs to the Flavivirus genus in the family Flaviviridae. It has a (+) sense RNA genome and is mainly transmitted to humans by the vector mosquito Aedes aegypti ...
Camacho-Nuez Minerva +8 more
doaj +1 more source
Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis
Frontiers in Cellular and Infection Microbiology, 2017 Flaviviruses including Dengue virus (DENV), Yellow fever virus (YFV), West Nile virus (WNV), and Japanese encephalitis virus (JEV) are global health problems that caused several serious diseases such as fever, hemorrhagic fever, and encephalitis in the ...
Zi-Yang Sheng +9 more
doaj +1 more source
Yellow fever transmission in non-human primates, Bahia, Northeastern Brazil.
PLoS Neglected Tropical Diseases, 2020 Yellow fever virus (YFV) causes a clinical syndrome of acute hemorrhagic hepatitis. YFV transmission involves non-human primates (NHP), mosquitoes and humans.
Jaqueline Goes de Jesus +34 more
doaj +1 more source
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2003 As hantaviroses constituem infecções zoonóticas amplamente distribuídas em todo o mundo. A febre hemorrágica com síndrome renal mostra-se endêmica na Ásia e Europa, acometendo milharea de pessoas anualmente.
Marcelo Simão Ferreira
doaj +1 more source
Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome. [PDF]
PLoS ONE, 2014 In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH.
Soraya S Pereira +14 more
doaj +1 more source
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
International external quality assessment study for molecular detection of Lassa virus.
PLoS Neglected Tropical Diseases, 2015 Lassa virus (LASV) is a causative agent of hemorrhagic fever in West Africa. In recent years, it has been imported several times to Europe and North America. The method of choice for early detection of LASV in blood is RT-PCR.
Sergejs Nikisins +5 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu +6 more
wiley +1 more source
Wellcome Open Research, 2021 Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa.
Áine O'Toole +99 more
doaj +1 more source