Results 121 to 130 of about 48,444 (255)
Molecular Mechanisms of Ebola Virus Entry into Permissive Cells
Ebola virus, representative of the Ebolavirus genus, Filoviridae family, causes severe hemorrhagic fever in humans, with lethality rates amounting up to 90 %. The members of Ebolavirus genus infect a broad range of mammalian cells.
T. E. Sizikova+3 more
doaj +1 more source
Research progress Ebola Hemorrhagic Fever vaccine
<p>Ebola hemorrhagic fever is a potent infectious disease by Ebola virus caused 90% mortality rate. Ebola virus was first isolated in 1976 by, for single-stranded negative segment, non-segmented, enveloped RNA viruses belonging to filamentous virus family. Ebola virus can be divided into five different subtypes.
Yuchen Zhang, Yunpeng Wang
openaire +2 more sources
Zoonotic Host Richness in the Global Wildland–Urban Interface
In the wildland–urban interface (WUI), where human settlements abut or intermix with wildlands, people may encounter animals that host zoonotic pathogens, which can spillover to cause human disease. We map the distribution of zoonotic hosts in the global WUI and show that large populations in tropical low–middle‐income countries (LMICs) are potentially
Rohan D. Simkin+5 more
wiley +1 more source
Biomarker Correlates of Survival in Pediatric Patients with Ebola Virus Disease
Outbreaks of Ebola virus disease (EVD) occur sporadically in Africa and are associated with high case-fatality rates. Historically, children have been less affected than adults.
Anita K. McElroy+6 more
doaj +1 more source
Automatic Classification of the Movements of Directed and Undirected Subviral Particles
The development of drugs against pathogens that cause hemorrhagic fever, such as Marburg and Ebola virus, requires researchers to gather much information about the virus.
Kaak Michelle+2 more
doaj +1 more source
A Syrian golden hamster model recapitulating ebola hemorrhagic fever.
Ebola hemorrhagic fever (EHF) is a severe viral infection for which no effective treatment or vaccine is currently available. While the nonhuman primate (NHP) model is used for final evaluation of experimental vaccines and therapeutic efficacy, rodent ...
H. Ebihara+10 more
semanticscholar +1 more source
The Interplay Between Viral Infection and Cell Death: A Ping‐Pong Effect
Programmed cell death (PCD) is a well‐studied cellular mechanism that plays a critical role in immune responses, developmental processes, and the maintenance of tissue homeostasis. However, viruses have developed diverse strategies to bypass or manipulate the host apoptotic machinery to enhance their replication and survival.
Alireza Nourazarian+5 more
wiley +1 more source
Post-Ebola Measles Outbreak in Lola, Guinea, January–June 2015
During public health crises such as the recent outbreaks of Ebola virus disease in West Africa, breakdowns in public health systems can lead to epidemics of vaccine-preventable diseases. We report here on an outbreak of measles in the prefecture of Lola,
Jonathan E. Suk+14 more
doaj +1 more source
There is a clear need for novel, effective therapeutic approaches to hemorrhagic fever due to filoviruses. Ebola virus hemorrhagic fever is associated with robust interferon (IFN)-α production, with plasma concentrations of IFN-α that greatly (60- to 100-
Lauren M Smith+13 more
semanticscholar +1 more source
Antivirals in COVID‐19: A Focus on Pediatric Cardiac Patients
The COVID‐19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to prevent or manage the infection.
Dalia Safi+4 more
wiley +1 more source