VIPR: a probabilistic algorithm for analysis of microbial detection microarrays [PDF]
Background All infectious disease oriented clinical diagnostic assays in use today focus on detecting the presence of a single, well defined target agent or a set of agents.
Adam F Allred +6 more
core +2 more sources
Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu +12 more
wiley +1 more source
Looking Beyond the Lens of Crimean-Congo Hemorrhagic Fever in Africa
Crimean-Congo hemorrhagic fever (CCHF) is a lethal viral disease that has severe public health effects throughout Africa and a case fatality rate of 10%–40%.
Olalekan John Okesanya +6 more
doaj +1 more source
Tick‐Borne Viruses in Finland: Public Health Risks, Interventions and Research Insights
ABSTRACT Ticks are obligate haematophagous arthropods that serve as vectors for diverse pathogens, including viruses, bacteria and protozoa. In Finland, the two primary tick species, Ixodes ricinus (castor bean tick) and Ixodes persulcatus (taiga tick), have been identified in the transmission of tick‐borne viruses (TBV), notably tick‐borne ...
Theophilus Yaw Alale +6 more
wiley +1 more source
Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20 [PDF]
Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently ...
Bieniasz, Paul D. +15 more
core +1 more source
Crimean-Congo Hemorrhagic Fever Virus in Ticks, Southwestern Europe, 2010
To the Editor: Crimean-Congo hemorrhagic fever virus (CCHFV; family Bunyaviridae, genus Nairovirus) causes outbreaks of severe hemorrhagic fever in humans, with case-fatality rates
Estrada-Peña, Agustín +7 more
openaire +5 more sources
Bayesian Phylogeography of Crimean-Congo Hemorrhagic Fever Virus in Europe
Crimean-Congo hemorrhagic fever (CCHF) is a zoonosis mainly transmitted by ticks that causes severe hemorrhagic fever and has a mortality rate of 5-60%. The first outbreak of CCHF occurred in the Crimean peninsula in 1944-45 and it has recently emerged in the Balkans and eastern Mediterranean.
G. Zehender +11 more
openaire +6 more sources
Newly recognized mosquito-associated viruses in mainland China, in the last two decades
There are four principal arboviruses in mainland China. Two kinds of them are mosquito-borne viruses, namely Japanese encephalitis virus and dengue virus, which lead to Japanese encephalitis, and dengue fever/dengue hemorrhagic fever respectively; the ...
Liang Guodong, Gao Xiaoyan, Liu Hong
doaj +1 more source
Pathways for entry of livestock arboviruses into Great Britain : assessing the strength of evidence [PDF]
The emergence of bluetongue virus and Schmallenberg virus in Great Britain (GB) during the last decade has highlighted the need for understanding the relative importance of the various pathways of the entry of livestock arboviruses so as to help focus ...
Gale, P., Kelly, Louise, Snary, E.L.
core +1 more source
Schmallenberg virus: emergence of an Orthobunyavirus among ruminants in Western Europe [PDF]
Recently, a novel virus has been identified among ruminants in Western Europe. This virus, the so-called Schmallenberg virus, belongs to the family Bunyaviridae, genus Orthobunyavirus, serogroup Simbu and is closely related to Akabane, Aino and Shamonda ...
Bertels, Guido +3 more
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