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Parotitis associated with Crimean Congo hemorrhagic fever virus
Journal of Clinical Virology, 2012Crimean Congo Hemorrhagic Fever (CCHF) is a potentially fatal tick-borne viral disease, the course of which may accompanied by various clinical findings.We describe a picture of non-suppurative parotitis developing in association with CCHF virus.A 48-year-old patient presenting to our hospital with lethargy, hemorrhage and pain and swelling below the ...
Selçuk, Kaya +3 more
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Cytokine response in crimean‐congo hemorrhagic fever virus infection
Journal of Medical Virology, 2017We described the predictive role of cytokines in fatality of Crimean Congo Hemorrhagic Fever Virus (CCHFV) infection by using daily clinical sera samples. Consequent serum samples of the selected patients in different severity groups and healthy controls were examined by using human cytokine 17‐plex assay.
Önder Ergönül +7 more
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The impact of Crimean-Congo hemorrhagic fever virus on public health
Antiviral Research, 2013Climatic, environmental and economic changes, as well as the steadily increasing global trade and personal mobility provide ample opportunities for emerging pathogens with zoonotic potential to spread to previously unaffected countries. Crimean-Congo hemorrhagic fever virus (CCHFV) is considered to be one of the major emerging disease threats spreading
Marc Mertens +3 more
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Genetic analysis of crimean‐congo hemorrhagic fever virus in Iran
Journal of Medical Virology, 2004AbstractCrimean‐Congo hemorrhagic fever (CCHF) is a potentially fatal disease caused by a tick‐borne virus in the family Bunyavridae. The disease occurs in parts of Africa, Asia, Middle East, and Eastern Europe. During recent years, an increasing number of human CCHF cases have been diagnosed in Iran, but very little information is available on the ...
Sadegh, Chinikar +9 more
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Crimean–Congo Hemorrhagic Fever Virus
2006Publisher Summary Crimean–Congo hemorrhagic fever (CCHF) is a member of the Nairovirus genus of the Bunyaviridae family. CCHFV is a single-stranded RNA virus, with a genome consisting of three negative-stranded segments designated S (small), M (medium), and L (large), which encode the nucleocapsid (N) protein, two envelope glycoproteins (G1 and G2 ...
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Ancient common ancestry of Crimean-Congo hemorrhagic fever virus
Molecular Phylogenetics and Evolution, 2010Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne RNA virus responsible for outbreaks of severe hemorrhagic fever in humans. Although CCHF was first detected in the 1940s, high levels of genomic diversity argue against a recent origin. Here, Bayesian coalescent analyses were used to estimate the rate of evolution and relative age of the virus.
Serena A, Carroll +3 more
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Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever
Cell, 2021J Maximilian Fels +2 more
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Reverse Genetics System for Crimean-Congo Hemorrhagic Fever Virus
Reverse genetic systems are powerful tools in molecular virology that allow the generation of infectious recombinant virus and the manipulation of viral genomes. Reverse genetic systems enable the incorporation of reporter genes, facilitating many virological assays, including high-throughput screening. Additionally, reverse genetic systems can be usedFlorine, Scholte +2 more
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