Results 21 to 30 of about 6,534 (214)

SARS-CoV-2 infection-induced immunity reduces rates of reinfection and hospitalization caused by the Delta or Omicron variants

Emerging Microbes and Infections, 2023
During a pandemic, effective vaccines are typically in short supply, particularly at onset intervals when the wave is accelerating. We conducted an observational, retrospective analysis of aggregated data from all patients who tested positive for SARS ...
Marc-Antoine de La Vega, Efstathia Polychronopoulou, Ara XIII, Zhe Ding, Tong Chen, Qixing Liu, Jiaming Lan, Marie-Edith Nepveu-Traversy, Hugues Fausther-Bovendo, Mohammed F. Zaidan, Gary Wong, Gulshan Sharma, Gary P. Kobinger   +12 more
doaj   +1 more source

Viral Hyperparasitism in Bat Ectoparasites: Implications for Pathogen Maintenance and Transmission

Microorganisms, 2022
Humans continue to encroach on the habitats of wild animals, potentially bringing different species into contact that would not typically encounter each other under natural circumstances, and forcing them into stressful, suboptimal conditions.
Alexander Tendu, Alice Catherine Hughes, Nicolas Berthet, Gary Wong   +3 more
doaj   +1 more source

Surveillance of Rift Valley Fever in Iran between 2001 and 2011

All Results Journals: Biol, 2013
Rift Valley fever virus (RVFV) is an acute zoonotic viral disease that mostly affects ruminants with an occasional spillover as human infection. Following the outbreak of RVF in Saudi Arabia in 2000, surveillance of both animal and human population in ...
Sadegh CHINIKAR, Nariman SHAH-HOSSEINI, Ehsan MOSTAFAVI, Maryam MORADI, Sahar KHAKIFIROUZ, Tahmineh JALALI, Anthony R. FOOKS   +6 more
doaj   +2 more sources

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Residual and Late Onset Symptoms Appeared in a Patient with Severe Fever with Thrombocytopenia in a Convalescence Stage

Viruses, 2021
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by Dabie bandavirus (formerly SFTS virus, SFTSV). Its manifestations during the convalescent phase have not been widely described.
Kohei Kanda, Noriko Kinoshita, Satoshi Kutsuna, Keiji Nakamura, Ayako Okuhama, Akira Shimomura, Takeshi Inagaki, Tomoki Yoshikawa, Takeshi Kurosu, Masayuki Shimojima, Masayuki Saijo, Norio Ohmagari   +11 more
doaj   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Re-Emergence of Rift Valley Fever Virus Lineage H in Senegal in 2022: In Vitro Characterization and Impact on Its Global Emergence in West Africa

Viruses
Rift Valley fever (RVF) is a re-emerging vector-borne zoonosis with a high public health and veterinary impact. In West Africa, many lineages were previously detected, but since 2020, lineage H from South Africa has been the main cause of the outbreaks ...
Ousseynou Sene, Samba Niang Sagne, Ndeye Sakha Bob, Moundhir Mhamadi, Idrissa Dieng, Aboubacry Gaye, Haoua Ba, Moussa Dia, Elisabeth Thérèse Faye, Sokhna Mayemouna Diop, Yoro Sall, Boly Diop, Mamadou Ndiaye, Cheikh Loucoubar, Etienne Simon-Lorière, Anavaj Sakuntabhai, Ousmane Faye, Amadou Alpha Sall, Diawo Diallo, Ndongo Dia, Oumar Faye, Moussa Moise Diagne, Malick Fall, Marie Henriette Dior Ndione, Mamadou Aliou Barry, Gamou Fall   +25 more
doaj   +1 more source

Myotis fimbriatus Virome, a Window to Virus Diversity and Evolution in the Genus Myotis

Viruses, 2022
Significant efforts have been made to characterize viral diversity in bats from China. Many of these studies were prospective and focused mainly on Rhinolophus bats that could be related to zoonotic events. However, other species of bats that are part of
Alix Armero, Ruiya Li, Kathrina Mae Bienes, Xing Chen, Jihao Li, Shiman Xu, Yanhua Chen, Alice C. Hughes, Nicolas Berthet, Gary Wong   +9 more
doaj   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source