Results 31 to 40 of about 94,407 (336)

Centhaquine Restores Renal Blood Flow and Protects Tissue Damage After Hemorrhagic Shock and Renal Ischemia

open access: yesFrontiers in Pharmacology, 2021
Background: Centhaquine (CQ) (Lyfaquin®) is in late stage clinical development as a safe and effective first-in-class resuscitative agent for hemorrhagic shock patients (NCT02408731, NCT04056065, and NCT04045327). Acute kidney injury (AKI) is known to be
Amaresh K. Ranjan   +4 more
doaj   +1 more source

Vertebral Heart Score: A Useful Parameter in Determination of Resuscitation Endpoint in Dogs with Hemorrhagic Shock [PDF]

open access: yesIranian Journal of Veterinary Medicine, 2019
BACKGROUND: GReliable prediction of patient response to fluid resuscitation is a crucial issue in the management of hemorrhagic shock. OBJECTIVES: This study was designed to investigate vertebral heart score (VHS) variation in fluid resuscitation of ...
Reza Azargoun   +4 more
doaj   +1 more source

Ursolic acid inhibits superoxide production in activated neutrophils and attenuates trauma-hemorrhage shock-induced organ injury in rats.

open access: yesPLoS ONE, 2014
Neutrophil activation is associated with the development of organ injury after trauma-hemorrhagic shock. In the present study, ursolic acid inhibited the superoxide anion generation and elastase release in human neutrophils.
Tsong-Long Hwang   +6 more
doaj   +1 more source

Is I-FABP not only a marker for the detection abdominal injury but also of hemorrhagic shock in severely injured trauma patients?

open access: yesWorld Journal of Emergency Surgery, 2019
Background Hemorrhagic shock can lead to intestinal damage with subsequent hyperinflammation and multiple organ dysfunction syndrome (MODS). The intestinal fatty acid-binding protein (I-FABP) is solely expressed in the intestine and is released ...
Maika Voth   +3 more
doaj   +1 more source

Transmural intestinal wall permeability in severe ischemia after enteral protease inhibition. [PDF]

open access: yes, 2014
In intestinal ischemia, inflammatory mediators in the small intestine's lumen such as food byproducts, bacteria, and digestive enzymes leak into the peritoneal space, lymph, and circulation, but the mechanisms by which the intestinal wall permeability ...
Altshuler, Angelina E   +6 more
core   +3 more sources

Impaired Fracture Healing after Hemorrhagic Shock

open access: yesMediators of Inflammation, 2015
Impaired fracture healing can occur in severely injured patients with hemorrhagic shock due to decreased soft tissue perfusion after trauma. We investigated the effects of fracture healing in a standardized pressure controlled hemorrhagic shock model in ...
Philipp Lichte   +12 more
doaj   +1 more source

L-arginine: A unique amino acid for improving depressed wound immune function following hemorrhage [PDF]

open access: yes, 2002
Objective: To determine whether L-arginine has any salutary effects on wound immune cell function following trauma-hemorrhage. Background. Depressed wound immune function contributes to an increased incidence of wound infections following hemorrhage ...
Angele, Martin K.   +7 more
core   +1 more source

Removal of luminal content protects the small intestine during hemorrhagic shock but is not sufficient to prevent lung injury. [PDF]

open access: yes, 2013
The small intestine plays a key role in the pathogenesis of multiple organ failure following circulatory shock. Current results show that reduced perfusion of the small intestine compromises the mucosal epithelial barrier, and the intestinal contents ...
Altshuler, Angelina E   +5 more
core   +2 more sources

Spontaneous globe rupture: Unusual ophthalmic manifestation with dengue hemorrhagic shock syndrome

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: We report an unusual manifestation of spontaneous globe rupture in a 9 year old male child with dengue hemorrhagic shock syndrome. Observations: Nine year old male was admitted in the pediatric intensive care unit in a state of altered sensorium
Rajwinder Kaur, MD   +3 more
doaj  

Hepatic infarction following abdominal interventional procedures. [PDF]

open access: yes, 2004
To clarify the incidence, background, and progress of hepatic infarction following interventional procedures, cases of hepatic infarction following interventional procedures at our department during the last decade were identified by reviewing the ...
Akaki, Shiro   +9 more
core   +1 more source

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