Results 1 to 10 of about 133,701 (287)

Effect of Empagliflozin on the plasma lipidome in patients with type 2 diabetes mellitus: results from the EmDia clinical trial

Cardiovascular Diabetology
Background Sodium-glucose cotransporter 2 (SGLT2) inhibitors, such as Empagliflozin, are antidiabetic drugs that reduce glucose levels and have emerged as a promising therapy for patients with heart failure (HF), although the exact molecular mechanisms ...
Katrin I. Bauer, Dhanwin Baker, Raissa Lerner, Thomas Koeck, Gregor Buch, Zlatka Fischer, Robin Martens, Ekaterina E. Esenkova, Maximilian Nuber, Miguel A. Andrade-Navarro, Vincent ten Cate, Stefan Tenzer, Philipp S. Wild, Laura Bindila, Elisa Araldi   +14 more
doaj   +1 more source

New method for endoscopic hemostasis: application of biopolymers on the gastric ulcer bleeding

, 2022
F.A. Khadjibayev, А.Б. Ешмуратов, А.G. Mirzakulov, А.Kh. Alimov, G.K. Botiralieva, Khaydar E. Yunusov   +5 more
openalex   +2 more sources

CD40L Priming of Platelets via NF‐κB Activation is CD40‐ and TAK1‐Dependent

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background CD40 ligand (CD40L) is a thromboinflammatory molecule that predicts cardiovascular events. CD40L is a strong activator of nuclear factor kappa B (NF‐κB) in platelets that primes and enhances platelet activation in response to thrombotic ...
Kevin Kojok, Souhad El Akoum, Mira Mohsen, Walid Mourad, Yahye Merhi   +4 more
doaj   +1 more source

Impact of local therapy in metastatic renal cell carcinoma during medical treatment in a retrospective analysis

Scientific Reports
Current guidelines on treatment of metastatic renal cell carcinoma (mRCC) suggest an emerging role of local therapy (LT). Still there is a lack of data which patients may benefit from additional LT once medical treatment (MT) is initiated.
Sena Hoffer, Hendrik Eggers, Tabea Fröhlich, Paula Kappler, Maria-Luisa Tiemann, Viktor Grünwald, Christoph Henkenberens, Mohamed Omar, Robert M. Blach, Florian Heidel, Philipp Ivanyi   +10 more
doaj   +1 more source

Pre T-Cell Receptor Alpha (pTα) Expression Patterns and Functional Analysis in Human T-Cell Lymphoblastic Leukemia

Cellular Oncology, 2010
Background: The pTα/preTCR regulates the β-selection, a crucial T-cell developmental checkpoint, providing a most potent survival advantage to thymocytes mediated by the src-kinase p56Lck.
Philipp Ivanyi, Michael Morgan, Wenji Piao, Sya N. Ukena, Klaus Steube, Arnold Ganser, Anke Franzke   +6 more
doaj   +1 more source

Hemostasis in Nonmammalian Vertebrates: An Overview [PDF]

, 1977
Jean W. Dodds
openalex   +1 more source

A PSGL-1 glycomimetic reduces thrombus burden without affecting hemostasis [PDF]

, 2021
Daniel J. Wong, Dayoung Park, Simon Park, Carolyn A. Haller, Jiaxuan Chen, Erbin Dai, Liying Liu, Appi Reddy Mandhapati, Pradheep Eradi, Bibek Dhakal, Walter J. Wever, Melinda S. Hanes, Lijun Sun, Richard D. Cummings, Elliot L. Chaikof   +14 more
openalex   +1 more source

Thrombomodulin resistance as a novel prothrombotic pathway in COVID-19

Scientific Reports
Hypercoagulability and endothelial dysfunction are strongly involved in the worsening of the clinical condition in COVID-19 patients. In severe cases, the inflammatory process triggers the release of angiopoietin 2, which could decrease circulating ...
Ana Marco-Rico, Adrián Montaño, Francisco López-Jaime, Ihosvany Fernández-Bello, Pascual Marco-Vera   +4 more
doaj   +1 more source

Cross-Sectional Analysis of Sleep Quality and Vascular Health in Shift- and Day-Working Nurses

Clocks & Sleep
Sleep disturbances and shift work are associated with increased cardiovascular risk, possibly through disruptions in endothelial and hemostatic function.
Gleb Saharov, Barbara Salti, Maram Bareya, Anat Keren-Politansky, Yona Nadir, Tamar Shochat   +5 more
doaj   +1 more source

Impact of adding carboplatin to docetaxel chemotherapy on testosterone levels and treatment outcomes in metastatic docetaxel-resistant prostate cancer

Scientific Reports
Docetaxel resistance, particularly post-androgen-receptor targeted therapy (ART), undermines its clinical utility in metastatic castration-resistant prostate cancer (mCRPC).
Hejar Atalan, Michael A. Morgan, Philipp Ivanyi, Paula Kappler, Florian H. Heidel, Christoph W. M. Reuter   +5 more
doaj   +1 more source