Results 1 to 10 of about 209,459 (341)
Frontiers in Physiology, 2023 Hibernating mammals have developed many physiological adaptations to accommodate their decreased metabolism, body temperature, heart rate and prolonged immobility without suffering organ injury. During hibernation, the animals must suppress blood clotting to survive prolonged periods of immobility and decreased blood flow that could otherwise lead to ...
Edwin L. De Vrij +5 more
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In silico methods for predicting functional synonymous variants
Genome Biology, 2023 Single nucleotide variants (SNVs) contribute to human genomic diversity. Synonymous SNVs are previously considered to be “silent,” but mounting evidence has revealed that these variants can cause RNA and protein changes and are implicated in over 85 ...
Brian C. Lin +4 more
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Immunity & Ageing, 2008 On March 19, 2008 a Symposium on Pathophysiology of Ageing and Age-Related Diseases was held in Palermo, Italy. The lecture of D. Mari on Hemostasis and ageing is summarized herein. Physiological ageing is associated with increased plasma levels of many proteins of blood coagulation together with fibrinolysis impairment. This may be of great concern in
D. Mari +5 more
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Thrombosis Journal, 2023 Background In patients with hemophilia (PwH), bleeding often occurs in joints and muscles, and early detection of hemorrhage is important to prevent the onset and progression of mobility impairment.
Ryohei Kawasaki +10 more
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Bleeding, Thrombosis and Vascular Biology, 2022 Vaccination with ChAdOx1 nCoV-19 can result in vaccine-induced immune thrombotic thrombocytopenia (VITT). This phenomenon mimics heparin-induced thrombocytopenia, yet it does not require heparin as a trigger.
Rita Carlotta Santoro +8 more
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Journal of Thrombosis and Haemostasis, 2015 Epidemiologic studies have revealed that modification of the levels of individual components of the hemostatic system may have effects on the development of thrombosis or hemorrhage. To maintain the necessary equilibrium, the hemostatic system is finely regulated.
Teruel-Montoya, R. +2 more
openaire +4 more sources
International Journal of Hematology-Oncology and Stem Cell Research, 2021 Background: Acute myeloid leukemia (AML) patients are often neutropenic as a result of their disease alone or following their chemotherapy. In this randomized clinical trial the efficacy of Iranian short-acting (PD-Grastim) and long-acting G-CSF (PD ...
Mohsen Esfandbod +4 more
doaj +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2023 Introduction: Bovine and ovine mucosa represent alternate anticoagulants to porcine mucosa for production of unfractionated heparin (UFH). Standardized heparins from various sources can be blended and potency adjusted, blended heparins exhibit comparable
Guy Olson BS +8 more
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Elevated hemostasis markers after pneumonia increases one-year risk of all-cause and cardiovascular deaths [PDF]
, 2011 Background: Acceleration of chronic diseases, particularly cardiovascular disease, may increase long-term mortality after community-acquired pneumonia (CAP), but underlying mechanisms are unknown. Persistence of the prothrombotic state that occurs during
A. Murat Kaynar +49 more
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Haematologica, 2023 Treatment options for relapsed and refractory acute myeloid leukemia patients (R/R AML) are limited. This retrospective cohort study compares safety and efficacy of fludarabine, cytarabine, and idarubicin (FLA-IDA) without or with venetoclax (FLAVIDA ...
Rabia Shahswar +19 more
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