Results 1 to 10 of about 170,341 (358)
Frontiers in Physiology, 2023 Hibernating mammals have developed many physiological adaptations to accommodate their decreased metabolism, body temperature, heart rate and prolonged immobility without suffering organ injury. During hibernation, the animals must suppress blood clotting to survive prolonged periods of immobility and decreased blood flow that could otherwise lead to ...
Edwin L. De Vrij +5 more
openaire +3 more sources
Beyond Hemostasis: Platelet Innate Immune Interactions and Thromboinflammation
International Journal of Molecular Sciences, 2022 There is accumulating evidence that platelets play roles beyond their traditional functions in thrombosis and hemostasis, e.g., in inflammatory processes, infection and cancer, and that they interact, stimulate and regulate cells of the innate immune ...
Jonathan Mandel +4 more
semanticscholar +1 more source
In silico methods for predicting functional synonymous variants
Genome Biology, 2023 Single nucleotide variants (SNVs) contribute to human genomic diversity. Synonymous SNVs are previously considered to be “silent,” but mounting evidence has revealed that these variants can cause RNA and protein changes and are implicated in over 85 ...
Brian C. Lin +4 more
doaj +1 more source
International Journal of Hematology-Oncology and Stem Cell Research, 2021 Background: Acute myeloid leukemia (AML) patients are often neutropenic as a result of their disease alone or following their chemotherapy. In this randomized clinical trial the efficacy of Iranian short-acting (PD-Grastim) and long-acting G-CSF (PD ...
Mohsen Esfandbod +4 more
doaj +1 more source
Thrombosis Journal, 2023 Background In patients with hemophilia (PwH), bleeding often occurs in joints and muscles, and early detection of hemorrhage is important to prevent the onset and progression of mobility impairment.
Ryohei Kawasaki +10 more
doaj +1 more source
Bleeding, Thrombosis and Vascular Biology, 2022 Vaccination with ChAdOx1 nCoV-19 can result in vaccine-induced immune thrombotic thrombocytopenia (VITT). This phenomenon mimics heparin-induced thrombocytopenia, yet it does not require heparin as a trigger.
Rita Carlotta Santoro +8 more
doaj +1 more source
Journal of Thrombosis and Haemostasis, 2015 Epidemiologic studies have revealed that modification of the levels of individual components of the hemostatic system may have effects on the development of thrombosis or hemorrhage. To maintain the necessary equilibrium, the hemostatic system is finely regulated.
Teruel-Montoya, R. +2 more
openaire +4 more sources
Immunity & Ageing, 2008 On March 19, 2008 a Symposium on Pathophysiology of Ageing and Age-Related Diseases was held in Palermo, Italy. The lecture of D. Mari on Hemostasis and ageing is summarized herein. Physiological ageing is associated with increased plasma levels of many proteins of blood coagulation together with fibrinolysis impairment. This may be of great concern in
D. Mari +5 more
openaire +5 more sources
Journal of Thrombosis and Haemostasis, 2020 The severe inflammatory state secondary to COVID‐19 leads to a severe derangement of hemostasis that has been recently described as a state of disseminated intravascular coagulation (DIC) and consumption coagulopathy, defined as decreased platelet count,
M. Panigada +8 more
semanticscholar +1 more source
Haematologica, 2023 Treatment options for relapsed and refractory acute myeloid leukemia patients (R/R AML) are limited. This retrospective cohort study compares safety and efficacy of fludarabine, cytarabine, and idarubicin (FLA-IDA) without or with venetoclax (FLAVIDA ...
Rabia Shahswar +19 more
doaj +1 more source