Results 91 to 100 of about 238,098 (403)
A Mathematical Model of Platelet Aggregation in an Extravascular Injury Under Flow [PDF]
We present the first mathematical model of flow-mediated primary hemostasis in an extravascular injury, which can track the process from initial deposition to occlusion. The model consists of a system of ordinary differential equations (ODE) that describe platelet aggregation (adhesion and cohesion), soluble-agonist-dependent platelet activation, and ...
arxiv
Stress and Hemostasis: An Update [PDF]
Numerous naturalistic, experimental, and mechanistic studies strongly support the notion that-as part of fight-or-flight response-hemostatic responses to acute psychosocial stress result in net hypercoagulability, which would protect a healthy organism from bleeding in case of injury.
Austin, Anthony W.+2 more
openaire +4 more sources
Leveraging Multifaceted Polyphenol Interactions: An Approach for Hair Loss Mitigation
This study presents tannic acid as an effective alternative to traditional hair loss treatments. Acting as an adhesion mediator, tannic acid binds to keratin on the hair surface and sequesters SCANDAL—a blend of salicylic acid, niacinamide, and dexpanthenol—allowing gradual release to hair follicles.
Eunu Kim, Geon Min Lee, Haeshin Lee
wiley +1 more source
Romiplostim use in pregnant women with immune thrombocytopenia
Abstract Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before ...
James B. Bussel+7 more
wiley +1 more source
β-hydroxybutyrate suppresses pathological changes of blood-induced arthropathy in rats
Arthropathy is a common complication in haemophilia and decreases quality of life. It has been known that concentrations of β-hydroxybutyrate (BHB) in blood are increased by a ketogenic diet, and elevated levels of circulating BHB restricts the ...
Ryohei Kawasaki+11 more
doaj +1 more source
Peripheral artery disease (PAD) patients have an increased cardiovascular risk despite pharmacological treatment strategies. Biomarker research improving risk stratification only focused on known atherothrombotic pathways, but unexplored pathways might ...
B. M. M. Kremers+9 more
doaj +1 more source
Review of Quantitative Systems Pharmacological Modeling in Thrombosis [PDF]
Hemostasis and thrombosis are often thought as two sides of the same clotting mechanism whereas hemostasis is a natural protective mechanism to prevent bleeding and thrombosis is a blood clot abnormally formulated inside a blood vessel, blocking the normal blood flow. The evidence to date suggests that at least arterial thrombosis results from the same
arxiv
Management of the thrombotic risk associated with COVID-19: guidance for the hemostasis laboratory
Coronavirus disease 2019 (COVID-19) is associated with extreme inflammatory response, disordered hemostasis and high thrombotic risk. A high incidence of thromboembolic events has been reported despite thromboprophylaxis, raising the question of a more ...
M. Hardy+12 more
semanticscholar +1 more source
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan+2 more
wiley +1 more source
Sex differences in lymphoma incidence and mortality by subtype: A population‐based study
A higher incidence and a trend toward higher mortality in men for most lymphoma subtypes is seen in this Swedish population‐based cohort study on adults (age 18‐99) diagnosed with lymphoma 2000‐2019. Male‐to‐female incidence rate ratio (IRR) by male‐to‐female excess mortality ratio (EMR), both adjusted for age and year of diagnosis, by lymphoma subtype.
Cecilia Radkiewicz+9 more
wiley +1 more source