Results 11 to 20 of about 209,459 (341)

D’ domain region Arg782-Cys799 of von Willebrand factor contributes to factor VIII binding

open access: yesHaematologica, 2020
In the complex with von Willebrand factor (VWF) factor VIII (FVIII) is protected from rapid clearance from circulation. Although it has been established that the FVIII binding site resides in the N-terminal D’-D3 domains of VWF, detailed information ...
Małgorzata A. Przeradzka   +7 more
doaj   +1 more source

SARS-CoV-2 Infection-Associated Aortic Thrombosis Treated with Oral Factor Xa Inhibition

open access: yesCase Reports in Hematology, 2022
Coronavirus disease 2019 (COVID-19) is an acute complex systemic disorder caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).While SARS-CoV-2 is known to cause significant pulmonary disease, various extrapulmonary manifestations ...
Alena Strýčková   +9 more
doaj   +1 more source

Hemorheological Failure in the Pathology of Cardio-vascular Complications in Patients with Diabetic Foot Syndrome [PDF]

open access: yes, 2016
The literature that includes the study of cardiovascular complications in patients with diabetic foot syndrome was analyzed. The topicality of this problem is caused by the steady growth of diabetes mellitus morbidity among people.
Кorobko, Е. (Еlina)
core   +2 more sources

Cerebral calcium embolism

open access: yesClinical Case Reports, 2022
A new‐onset neurological deficit after calcified aortic valve replacement and an hyperdense image on the computed tomography raised suspicion of an stroke of unusual etiology.
Pedro Asensi Cantó   +3 more
doaj   +1 more source

Hemostasis biomarkers and incident cognitive impairment: the REGARDS study [PDF]

open access: yes, 2018
Essentials Cognitive disorders are increasing and vascular risk factors play a role in this. We performed a nested case control study of hemostasis biomarkers and cognitive impairment (CI). Higher baseline fibrinogen, factor VIII and D-dimer were related
Callas, P.W.   +7 more
core   +1 more source

Designing ATHN 7: Safety, effectiveness and practice of treatment of people with haemophilia in the United States through a natural history cohort study

open access: yesThe Journal of Haemophilia Practice, 2023
Haemophilia A and B are X-linked inherited bleeding disorders, resulting in the deficiency of clotting factor VIII and IX, respectively. Since the introduction of recombinant clotting factor concentrates in the early 1990s, the major safety concern for ...
Buckner Tyler W.   +5 more
doaj   +1 more source

Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion in vitro [PDF]

open access: yes, 2016
Blood platelets prepared for transfusion gradually lose hemostatic function during storage. Platelet function can be investigated using a variety of (indirect) in vitro experiments, but none of these is as comprehensive as microfluidic flow chambers.
Compernolle, Veerle   +4 more
core   +2 more sources

Generation of functional liver sinusoidal endothelial-like cells from human bone marrow-derived mesenchymal stem cells

open access: yesRegenerative Therapy, 2023
Introduction: Liver sinusoidal endothelial cells (LSECs) are specialized vascular endothelial cells that play an important role in the maintenance of biological homeostasis.
Seiji Mitani   +6 more
doaj   +1 more source

In vitro analysis of anti-HPA-1a dependent platelet phagocytosis and its inhibition using a new whole blood phagocytosis assay (WHOPPA)

open access: yesFrontiers in Immunology, 2023
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a serious bleeding condition mostly caused by the reaction between maternal anti-HPA-1a antibodies and fetal platelets. This reaction leads to Fc-dependent platelet phagocytosis.
Paula Ames   +11 more
doaj   +1 more source

Platelets and galectins [PDF]

open access: yes, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

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