Results 21 to 30 of about 238,098 (403)

Inorganic-based biomaterials for rapid hemostasis and wound healing

Chemical Science, 2022
The challenge for the treatment of severe traumas poses an urgent clinical need for the development of biomaterials to achieve rapid hemostasis and wound healing.
Yi Zheng, Jinfu Wu, Yufang Zhu, Chengtie Wu   +3 more
semanticscholar   +1 more source

Designing ATHN 7: Safety, effectiveness and practice of treatment of people with haemophilia in the United States through a natural history cohort study

The Journal of Haemophilia Practice, 2023
Haemophilia A and B are X-linked inherited bleeding disorders, resulting in the deficiency of clotting factor VIII and IX, respectively. Since the introduction of recombinant clotting factor concentrates in the early 1990s, the major safety concern for ...
Buckner Tyler W., Daoud Nabil, Miles Moses, O'Neill Carrie, Watson Crystal, Recht Michael   +5 more
doaj   +1 more source

In vitro analysis of anti-HPA-1a dependent platelet phagocytosis and its inhibition using a new whole blood phagocytosis assay (WHOPPA)

Frontiers in Immunology, 2023
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a serious bleeding condition mostly caused by the reaction between maternal anti-HPA-1a antibodies and fetal platelets. This reaction leads to Fc-dependent platelet phagocytosis.
Paula Ames, Nelli Baal, Martin Speckmann, Martin Speckmann, Gabriela Michel, Judith Ratke, Christina Klesser, Nina Cooper, Daisuke Takahashi, Behnaz Bayat, Gregor Bein, Sentot Santoso   +11 more
doaj   +1 more source

Elevated hemostasis markers after pneumonia increases one-year risk of all-cause and cardiovascular deaths [PDF]

, 2011
Background: Acceleration of chronic diseases, particularly cardiovascular disease, may increase long-term mortality after community-acquired pneumonia (CAP), but underlying mechanisms are unknown. Persistence of the prothrombotic state that occurs during
A. Murat Kaynar, AM Toschke, CN Serhan, CR Meier, DC Cowper, Derek C. Angus, EA Halm, EB Milbrandt, F Balkwill, FL Brancati, Florian Mayr, GD Lowe, Gina D'Angelo, GT Kinasewitz, GW Waterer, H Putter, I Koivula, J Bordon, J Kasal, J Kelly, JA Kellum, JL Hsu, JL Vincent, John A. Kellum, JU Hedlund, Kaikobad Irani, L Smeeth, Lisa Weissfeld, ME Charlson, MJ Fine, MJ Pencina, MM Doody, MM Levy, MM Samama, NM Sathiakumar, Patricia T. Bozza, PM Ridker, PR Woodhouse, S Yende, S Yende, Sachin Yende, SE Epstein, Tammy Young, TC Clayton, TT Keller, TT Keller, V Kaplan, VF Corrales-Medina, WA Knaus, WB Kannel   +49 more
core   +5 more sources

Hemostasis biomarkers and incident cognitive impairment: the REGARDS study [PDF]

, 2018
Essentials Cognitive disorders are increasing and vascular risk factors play a role in this. We performed a nested case control study of hemostasis biomarkers and cognitive impairment (CI). Higher baseline fibrinogen, factor VIII and D-dimer were related
Callas, P.W., Cushman, M., Gillett, S.R., Letter, A.J., McClure, L.A., Thacker, E.L., Unverzagt, F.W., Wadley, V.G.   +7 more
core   +1 more source

The concept of rebalanced hemostasis in patients with liver disease: Communication from the ISTH SSC working group on hemostatic management of patients with liver disease

Journal of Thrombosis and Haemostasis, 2021
Patients with liver diseases acquire complex alterations in their hemostatic system that may lead to abnormalities in routine diagnostic test of hemostasis. Thrombocytopenia, prolongations in the prothrombin time and activated partial thromboplastin time,
T. Lisman, V. Hernández-Gea, M. Magnusson, L. Roberts, S. Stanworth, J. Thachil, A. Tripodi   +6 more
semanticscholar   +1 more source

Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion in vitro [PDF]

, 2016
Blood platelets prepared for transfusion gradually lose hemostatic function during storage. Platelet function can be investigated using a variety of (indirect) in vitro experiments, but none of these is as comprehensive as microfluidic flow chambers.
Compernolle, Veerle, Devloo, Rosalie, Feys, Hendrik, Van Aelst, Britt, Vandekerckhove, Philippe   +4 more
core   +2 more sources

Recurrence risk after anticoagulant treatment of limited duration for late, second venous thromboembolism

Haematologica, 2015
Patients with a second venous thromboembolism generally receive anticoagulant treatment indefinitely, although it is known that the recurrence risk diminishes over time while the risk of hemorrhage persists with continued anticoagulation and increases ...
Tom van der Hulle, Melanie Tan, Paul L. den Exter, Mark J.G. van Roosmalen, Felix J.M. van der Meer, Jeroen Eikenboom, Menno V. Huisman, Frederikus A. Klok   +7 more
doaj   +1 more source

Platelets and galectins [PDF]

, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +1 more source

Gut Microbiota Promote Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background The gut microbiome is essential for physiological host responses and development of immune functions. The impact of gut microbiota on blood pressure and systemic vascular function, processes that are determined by immune cell function, is ...
Susanne H. Karbach, Tanja Schönfelder, Ines Brandão, Eivor Wilms, Nives Hörmann, Sven Jäckel, Rebecca Schüler, Stefanie Finger, Maike Knorr, Jeremy Lagrange, Moritz Brandt, Ari Waisman, Sabine Kossmann, Katrin Schäfer, Thomas Münzel, Christoph Reinhardt, Philip Wenzel   +16 more
doaj   +1 more source