Results 41 to 50 of about 133,701 (287)

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

Advanced Functional Materials, EarlyView.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr, Saptarshi Biswas, Jacob Aragon, Asaf Dana, Jasmine Sureka, Vaaridhi Ramanuja, Jeevika Thazhaiselvam, Sarah E. Miller, Taylor H. Ware, Akhilesh K. Gaharwar   +9 more
wiley   +1 more source

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

Advanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son, Kyusoon Pak, Taehoon Lee, Monica Celine Prayogo, Jinyoung Choi, Sukkyung Kang, Minjoo Kang, Byungkook Oh, Sang Yu Sun, Sanha Kim, Sung Gap Im, Sangyong Jon, Steve Park   +12 more
wiley   +1 more source

Steroids and Malignancy Increase Local Heparanase and Decrease Markers of Osteoblast Activity in Bone Tissue Microcirculation

Biomolecules
Bone metastasis and steroids are known to activate the coagulation system and induce osteoporosis, pathological bone fractures, and bone pain. Heparanase is a protein known to enhance the hemostatic system and to promote angiogenesis, metastasis, and ...
Keren Asayag, Eli Peled, Mai Assalia, Yonatan Crispel, Chen Yanovich, Haim Cohen, Anat Keren-Politansky, Yona Nadir   +7 more
doaj   +1 more source

From Hemophilia to Deep Venous Thrombosis Patient Samples: How to Perform an Easy Coagulometer Validation Process According to Available Guidelines

Clinical and Applied Thrombosis/Hemostasis, 2020
Validation protocols for the evaluation of coagulometers are needed to help professionals select the most suitable system for their regular laboratory routines.
Silmara Aparecida de Lima Montalvão PhD, Ana Paula Francisco, Bittar Letícia Queiroz da Silva MSc, Stephany Cares Huber PhD, Helder José Aguiari, Maria Carmem Gonçalves Lopes Fernandes, Priscila Soares Elidio, Beatriz de Moraes Martinelli, Isa Macedo Tony MSc, Marina Pereira Colella PhD, Joyce Maria Annichinno-Bizzachi PhD   +10 more
doaj   +1 more source

Long-Term Outcomes after Vaccine-Induced Thrombotic Thrombocytopenia

Viruses, 2022
Vaccine-induced thrombotic thrombocytopenia (VITT), or thrombosis with thrombocytopenia syndrome (TTS), is a rare but serious complication of adenovirus-based vaccines against severe respiratory syndrome coronavirus 2 (SARS-CoV-2).
Victoria Panagiota, Christiane Dobbelstein, Sonja Werwitzke, Arnold Ganser, Nina Cooper, Ulrich J. Sachs, Andreas Tiede   +6 more
doaj   +1 more source

An Ultrafast Self‐Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine

Advanced Functional Materials, EarlyView.
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang, Quyang Yang, Minxia zhang, Xiaowei Wang, Xiujun Cheng, Changyue Wu, Dan Wu, Yutian Yang, Canbin Dong, Tao Zhang, Weiqiang Tan, Ningwen Zhu   +14 more
wiley   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

Hemostasis

, 2023
Inflammation and coagulation are tightly connected, whereby an inflammatory host response will activate coagulation, resulting in a spectrum of coagulopathies that range from a mildly decreased platelet count to disseminated intravascular coagulation (DIC).
Dujardin, Romein W. G., Kleinveld, Derek J. B., Juffermans, Nicole P.   +2 more
openaire   +2 more sources

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

β-hydroxybutyrate suppresses pathological changes of blood-induced arthropathy in rats

Scientific Reports
Arthropathy is a common complication in haemophilia and decreases quality of life. It has been known that concentrations of β-hydroxybutyrate (BHB) in blood are increased by a ketogenic diet, and elevated levels of circulating BHB restricts the ...
Ryohei Kawasaki, Asuka Sakata, Kohei Tatsumi, Seiji Mitani, Maiko Takeda, Shogo Kasuda, Naoki Matsumoto, Suguru Harada, Tetsuhiro Soeda, Yukiko Nishida, Yasushi Yoshimura, Midori Shima   +11 more
doaj   +1 more source