Effectiveness and Safety of Apixaban for Treatment of Venous Thromboembolism in Daily Practice
Introduction Phase 3 trials have shown comparable efficacy of direct oral anticoagulants (DOACs) and vitamin K antagonists in patients with acute venous thromboembolism (VTE), with less major bleeding events in patients randomized to DOAC treatment. With
Stephan V. Hendriks+6 more
doaj +1 more source
The band electrode: Ongoing experience with a novel turp loop to improve hemostasis in 265 patients [PDF]
Introduction: Intraoperative bleeding, one of the major complications of conventional transurethral resection of the prostate ( TURP), has led to a search for various alternative methods of tissue ablation in patients with benign prostatic hyperplasia ...
Faul, P., Reich, O.
core +1 more source
A task and performance analysis of endoscopic submucosal dissection (ESD) surgery [PDF]
BACKGROUND: ESD is an endoscopic technique for en bloc resection of gastrointestinal lesions. ESD is a widely-used in Japan and throughout Asia, but not as prevalent in Europe or the US.
Bayrak, Coskun+13 more
core +1 more source
Systemic effects of tissue plasminogen activator-associated fibrinolysis and its relation to thrombin generation in orthotopic liver transplantation [PDF]
Orthotopic liver transplantation is frequently associated with hyperfibrinolysis, the origin and clinical relevance of which is largely unknown. In 20 orthotopic liver transplantations, we studied the occurrence and systemic effects of hyperfibrinolysis.
Bontempo, FA+5 more
core +1 more source
Drug-induced activation of integrin alpha IIb beta 3 leads to minor localized structural changes [PDF]
Integrins are transmembrane proteins involved in hemostasis, wound healing, immunity and cancer. In response to intracellular signals and ligand binding, integrins adopt different conformations: the bent (resting) form; the intermediate extended form; and the ligand-occupied active form.
arxiv +1 more source
The propensity of therapeutic proteins to elicit an immune response, poses a significant challenge in clinical development and safety of the patients. Assessment of immunogenicity is crucial to predict potential adverse events and design safer biologics.
Wojciech Jankowski+5 more
doaj +1 more source
Model-Predictive Control of Blood Suction for Surgical Hemostasis using Differentiable Fluid Simulations [PDF]
Recent developments in surgical robotics have led to new advancements in the automation of surgical sub-tasks such as suturing, soft tissue manipulation, tissue tensioning and cutting. However, integration of dynamics to optimize these control policies for the variety of scenes encountered in surgery remains unsolved.
arxiv
Estimating Discontinuous Time-Varying Risk Factors and Treatment Benefits for COVID-19 with Interpretable ML [PDF]
Treatment protocols, disease understanding, and viral characteristics changed over the course of the COVID-19 pandemic; as a result, the risks associated with patient comorbidities and biomarkers also changed. We add to the conversation regarding inflammation, hemostasis and vascular function in COVID-19 by performing a time-varying observational ...
arxiv
The cornerstone of treatment for symptomatic gallbladder stones is laparoscopic cholecystectomy. Pain is the commonest cause of extended hospital stay. Disturbance of liver—diaphragm surface tension is the main cause of pain. Retained CO2 is a major concern post laparoscopic cholecystectomy.
Mohamed Lotfy Ali Abuelzein+3 more
wiley +1 more source
Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring
COVID-19 is an infection induced by the SARS-CoV-2 coronavirus, and severe forms can lead to acute respiratory distress syndrome (ARDS) requiring intensive care unit (ICU) management.
S. Susen+58 more
semanticscholar +1 more source