Results 71 to 80 of about 62,467 (264)

Nanotechnology-enabled materials for hemostatic and anti-infection treatments in orthopedic surgery

International Journal of Nanomedicine, 2018
Haolin Sun,1,2,* Lu Lv,3,* Yanjie Bai,4,* Huilin Yang,2,3 Huan Zhou,2,5 Chunde Li,1 Lei Yang2,3 1Department of Orthopaedics, Peking University First Hospital, Beijing 100034, China; 2International Research Center for Translational Orthopaedics (IRCTO ...
Sun H, Lv L, Bai Y, Yang H, Zhou H, Li C, Yang L   +6 more
doaj  

Molecular Design of a Naturally Derived Hemostatic Sealant with Prolonged Antimicrobial Activity for Repairing Elastic Organ Injuries

Advanced Science
Hemorrhaging injuries on dynamic internal organs present significant clinical burdens due to their complex nature. To address therapeutic challenges, an injectable, photocrosslinkable, and multifunctional bioadhesive hydrogel comprising methacrylated ...
Saumya Jain, Avijit Baidya, Joshua A. Boys, George Z. Cheng, Taichiro Imahori, Naoki Kaneko, Nasim Annabi   +6 more
doaj   +1 more source

Progress in Application of Novel Functional Hemostatic Dressings in Patients with Continuous Bleeding after PICC Catheterization

Zhongguo yiliao qixie zazhi
The high incidence of bleeding after peripherally inserted central catheter (PICC) catheterization increases the risk of puncture site infection and unplanned extubation.
Jimin WU, Qiong YAN, Haiying XU, Xiaohong ZHANG, Xinyue LI, Jinlei DU   +5 more
doaj   +1 more source

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

Advanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang, Qixiang Zhang, Keman Liao, Xiaoyu Liu, Hongchi Zhang, Yunsheng Chen, Yuxiao Ma, Yikui Liu, Aoqian Xu, Yuhao Sun, Jiayi Chen, Liuguan Bian, Baofeng Wang   +12 more
wiley   +1 more source

Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A Review

Polysaccharides
Bleeding is a potentially life-threatening emergency that can result in severe complications or death regardless of the cause of bleeding. The development of hemostatic materials has been a long-standing concern for emergency treatment in surgery and ...
Yingying Guo, Xuan Xie, Jing Li, Shun Yao   +3 more
doaj   +1 more source

Chitosan-Based Composite Materials for Prospective Hemostatic Applications

Marine Drugs, 2018
Effective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis.
Zhang Hu, Dong-Ying Zhang, Si-Tong Lu, Pu-Wang Li, Si-Dong Li   +4 more
doaj   +1 more source

Geometry‐Encoded Soft Strain Sensing via Liquid‐Metal Transmission Lines

Advanced Science, EarlyView.
This study presents a liquid‐metal transmission‐line strain sensor that achieves intrinsic decoupling by encoding axial elongation into propagation delay. The time‐domain readout remains stable under complex off‐axis. This enables reliable, repeatable, real‐time elongation measurement in dynamic, multiaxial loading environments for wearable electronics,
Zhang Liu, Fengdeng Jin, Wenxuan Shi, Meng She, Ziqi Meng, Miao Fang, Yixin Zhang, Qianwen Dong, Wandi Yang, Lei Shi, Xujia Zhao, Feng Zhou, Bin Yao   +12 more
wiley   +1 more source

Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition

Advanced Science, EarlyView.
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu, Luyao Ji, Haoyi Yang, Xiying Chen, Qiaodan Hu, Haimei He, Jiawei Wu, Leyan Shan, Shihui Feng, Yingzhi Li, Xiongchang Tan, Hao Wang, Zilong Wang, Chaoran Wu   +13 more
wiley   +1 more source

Clinically Inferred Metabolic Dysfunction-Associated Steatotic Liver Disease and Its Association with Atrial Fibrillation Subtypes: A Prospective Clinical and Cardiometabolic Analysis

Life
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) has been linked to atrial fibrillation (AF); however, its relationship with specific AF subtypes remains unclear.
Monika Różycka-Kosmalska, Boguslawa Luzak, Marcin Kosmalski   +2 more
doaj   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source