Results 91 to 100 of about 2,670 (289)

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

Use of "Epsilamine" as Hemostatics at Urological Clinic. [PDF]

open access: yes, 1965
A new hemostatic agent "Epsilamine" was admi n istered to a total of 23 patients with urological diseases, including 8 postoperative cases. Marked effective, effective and ineffecgive responses were observed in 8, 10 and 5 cases respectively, making 78.3
清水, 幸夫   +4 more
core  

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

open access: yesAdvanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li   +8 more
wiley   +1 more source

Advanced Hemostatics in the Management of Cerebral Dural Sinus Lacerations

open access: yes, 2015
The authors reported their experience with 57 consecutive patients who were treated with this hemostatic technique to control bleeding from iatrogenic tears of the superior sagittal sinus or transverse/ sigmoid sinuses whenever standard maneuvers (eg ...
Graziano, F.   +2 more
core   +1 more source

DNA barcoding of Rhodiola (crassulaceae): a case study on a group of recently diversified medicinal plants from the Qinghai-Tibetan Plateau.

open access: yesPLoS ONE, 2015
DNA barcoding, the identification of species using one or a few short standardized DNA sequences, is an important complement to traditional taxonomy.
Jian-Qiang Zhang   +3 more
doaj   +1 more source

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang   +14 more
wiley   +1 more source

Smith, Samuel G. F. - An inaugural dissertation on hemorrhages and hemostatics

open access: yes
Handwritten inaugural dissertation on hemorrhages and hemostatics by Samuel Granville Fly Smith, of Tennessee.Inaugural dissertation; no ...
Smith, Samuel G. F.
core  

Extracellular CIRP Dysregulates Microglial Efferocytosis in Acute Ischemic Stroke via the TLR4/miR‐155/MafB Axis

open access: yesAdvanced Science, EarlyView.
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin   +3 more
wiley   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

open access: yesAdvanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao   +6 more
wiley   +1 more source

Not Available

open access: yes, 2019
Not AvailableThe report describes clinical mastitis and hemolactia caused by Staphylococcus epidermidis in a she camel. Pinkish to reddish milk discoloration with presence of numerous polymorphonuclear leukocytes and erythrocytes was recorded. Treatment
Amita Ranjan   +4 more
core  

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