Results 61 to 70 of about 19,190 (203)
The clinical impact of MTHFR polymorphism on the vascular complications of sickle cell disease [PDF]
, 2006 Sickle cell disease (SCD) is one of the most common inherited diseases in the world and the patients present notorious clinical heterogeneity. It is known that patients with SCD present activation of the blood coagulation and fibrinolytic systems ...
Beltrão, A.c.s. +6 more
core +3 more sources
Avaliação sanitária dos serviços de hemoterapia do estado do Paraná
Revista de Saúde Pública do Paraná, 2020 O objetivo deste estudo é avaliar os riscos potenciais apresentados pelos serviços de hemoterapia do estado do Paraná no período de 2010 a 2017, e identificar as não conformidades comuns nas Agências Transfusionais no ano de 2017. Foram utilizados dados do sistema informatizado SHTWEB. Utilizou-se o Método de Avaliação de Risco Potencial em Serviços de
Renata Pavese, Edson Zangiacomi Martinez
openaire +4 more sources
A hemoterapia no Brasil de 64 a 80 [PDF]
Physis: Revista de Saúde Coletiva, 1991 Só recentemente a hemoterapia tomou-se questão de política social, para além do interesse imediato da medicina e da saúde pública. Procura-se aqui apresentar o quadro geral, histórico e institucional, em que se delineou o tema - anteriormente à "politização do sangue", com o surgimento da AIDS transfusional.
Santos, Luiz A. de Castro +2 more
openaire +3 more sources
Analysis of polymorphism at site -174 G/C of interleukin-6 promoter region in multiple myeloma [PDF]
, 2007 It is well established that interleukin-6 (IL-6) is an essential growth factor for multiple myeloma (MM) and patients with increased IL-6 levels have a poor prognosis.
Almeida, Manuella de Souza Sampaio +5 more
core +1 more source
Exploring the synergy between telomere length and genomic complexity in CLL
British Journal of Haematology, EarlyView.
Silvia Ramos‐Campoy +19 more
wiley +1 more source
Insights Into Hemoglobinopathies in Spain: A Comprehensive Review
eJHaem, Volume 6, Issue 5, October 2025.ABSTRACT Background Hemoglobinopathies, including thalassemia and sickle cell disease (SCD), are increasingly prevalent in Spain due to migration and historical genetic patterns. Despite recent advances in screening and care, regional disparities in diagnosis and treatment persist.
Joan‐Lluis Vives Corrons
wiley +1 more source
British Journal of Haematology, Volume 207, Issue 4, Page 1565-1577, October 2025.Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez +34 more
wiley +1 more source
Is it necessary to perform a bilateral bone marrow biopsy to stage diffuse large B-cell lymphoma? [PDF]
, 2009 Estudo retrospectivo que visa analisar a utilidade da biópsia de medula óssea (BMO) bilateral na infiltração de medula óssea (MO) por linfoma difuso de grandes células B (LDGCB). Nossos objetivos foram avaliar a incidência de infiltração unilateral de MO
ALDRED, Vera Lúcia +6 more
core +2 more sources
Hepatitis C virus infection in blood donors in Santa Catarina, Brazil, 2010–2020
Transfusion Medicine, Volume 35, Issue 5, Page 486-493, October 2025.Abstract Introduction Hepatitis C is a silent disease characterised by a persistent inflammatory process in the liver. Since blood is the main route of transmission, the objective of this study was to estimate the positivity rate of hepatitis C virus (HCV) infection in blood donations from the Public Blood Network of the State of Santa Catarina and to ...
Fabiana Schuelter‐Trevisol +3 more
wiley +1 more source