Joint Damage Prediction in Non-Severe Hemophilia A with Artificial Intelligence [PDF]
Journal of Blood MedicineAna Marco-Rico,1 José Manuel Calvo-Villas,2 Francisco-Jose Lopez-Jaime,3 Mariana Canaro Hirnyk,4 María del Mar Nieto-Hernández,5 Sonia Herrero Martín,6 Laura Entrena-Ureña,7 Shally Marcellini-Antonio,8 Bolivar L Diaz-Jordan,9 Sergio Jurado-Herrera,10 ...
Marco-Rico A +15 more
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Implementation of third-generation digital PCR for non-invasive prenatal diagnosis of sickle cell disease and early detection. Pilot study [PDF]
Frontiers in MedicineSickle cell disease (SCD) is one of the most prevalent autosomal recessive conditions worldwide, affecting more than 600,000 newborns annually. Despite advances in treatment, it remains a chronic condition requiring lifelong management.
Sara Ferrer Benito +23 more
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Caplacizumab treatment in elderly patients with iTTP: Experience from the Spanish TTP Registry [PDF]
HemaSphereImmune thrombotic thrombocytopenic purpura (iTTP) typically affects middle‐aged individuals, although it sometimes appears in older patients. Caplacizumab is approved for the treatment of iTTP, but information on the safety and efficacy of this drug in ...
Inés Gómez‐Seguí +20 more
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Anti-HLA antibody formation increases the chances of platelet refractoriness in platelet-transfused patients: a systematic review with meta-analysis [PDF]
Hematology, Transfusion and Cell TherapyPlatelet refractoriness caused by alloimmunization to anti-HLA antibodies remains present in daily hemotherapy: the frequent need for platelet transfusions may influence the long-term survival of treated patients. This study aimed to perform a systematic
Luana Joana Barreto Cabral +5 more
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Nursing in hemotherapy services: considerations on public policies associated with blood and blood components [PDF]
Revista Brasileira de Enfermagem, 2022 Objective: Reflect on how the evolution of legislation related to blood and blood-based products has shaped the role of nurses in hemotherapy services. Methods: A reflective study, carried out employing surveys in databases, about the evolution of the ...
Patrícia Aparecida Tavares Mendes +3 more
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Viral Metagenomics for Identification of Emerging Viruses in Transfusion Medicine
Viruses, 2022 Viral metagenomics has revolutionized our understanding for identification of unknown or poorly characterized viruses. For that reason, metagenomic studies gave been largely applied for virus discovery in a wide variety of clinical samples, including ...
Svetoslav Nanev Slavov
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A genetic risk score based on BCL11A and HBS1L-MYB variants predicts clinical severity in Brazilian sickle cell anaemia patients. [PDF]
Br J HaematolSummary Individuals with sickle cell anaemia (SCA) exhibit significant clinical heterogeneity influenced by several factors, especially fetal haemoglobin (HbF) levels. Variations in adult HbF levels are partly explained by the co‐inheritance of genetic variants that regulate globin expression.
Arcanjo GS +13 more
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Hematology, Transfusion and Cell Therapy, 2023 Objective: Hodgkin's Lymphoma (HL) during the years became a high curable hematology malignant disease. Despite high curable rates, up to 30% of patient will relapse or will be refractory to first line therapy (R/R).
Carmino De Souza +4 more
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Revista Brasileira de Hematologia e Hemoterapia, 2008 A experiência de um modelo de gestão, nas áreas de hematologia e hemoterapia, que transforme as práticas de gestão voltadas excessivamente para procedimentos, normas e relatórios, em estratégias focadas em resultados que determinam a satisfação do ...
Daniela O. W. Rodrigues +2 more
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Quality control in blood irradiation
Brazilian Journal of Radiation Sciences, 2023 Irradiation is a technique used in hemotherapy to functionally inactivateviable lymphocytes, in cellular blood components, to reduce the risk of Transfusion-associated Graft-versus-Host Disease (AT-GVHD), is rare but letal.
F. Lopes +8 more
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