Results 41 to 50 of about 733 (138)
Comparative evaluation of blood component preparation with the top‐and‐top and top‐and‐bottom methods: A change in Uruguay
Transfusion Medicine, Volume 36, Issue 3, Page 260-264, June 2026.Abstract Background
Hospital de Clínicas, in conjunction with the Universidad de la República UDELAR in Uruguay, evaluated the quality of blood components after separation with a top‐and‐bottom (TB) system, comparing it with the top‐and‐top (TT) system and verifying compliance with local and international standards. Study Design and Methods
Whole blood Natalia Méndez Acosta, Gabriela Rivas Alén, Ismael Rodriguez Grecco, Allexandra Díaz, Dalia Moreno, Ludwig R. Frontier Ramos +5 morewiley +1 more sourcePatient‐ and caregiver‐reported barriers to chemotherapy in nine sub‐Saharan African countries: A cross‐sectional survey among population‐based registries
International Journal of Cancer, Volume 158, Issue 10, Page 2684-2696, 15 May 2026.What's New?
Increasing cancer incidence and mortality in low‐ and middle‐income countries has heightened concerns about limited resources and barriers to care. This challenge is particularly urgent in Sub‐Saharan Africa (SSA), where cancer rates are rising sharply. Here, data from population‐based cancer registries in nine SSA countries was assessed to Tamara König, Nikolaus Christian Simon Mezger, Ole Stoeter, Phoebe Mary Amulen, Margaret Borok, Gladys C. Chesumbai, Moudiongui MBoungou Dimitry, Ima‐Obong Ekanem, Adugna Fekadu, Bakarou Kamaté, William Muller, Alex Alain Kabena Nzambikolo, Abidemi Omonisi, Furaha Serventi, Markus Wallwiener, Biying Liu, Donald Maxwell Parkin, Pablo Sandro Carvalho Santos, Eva Johanna Kantelhardt, Eric Sven Kroeber +19 morewiley +1 more sourceMolecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia
Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.ABSTRACT
Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior +9 morewiley +1 more sourceTargeting Tumor Stroma: Current Challenges and Future Directions
MedComm, Volume 7, Issue 5, May 2026.Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).Siwei Wang, Haofan Hu, Weifeng Zeng, Lu Qin, Xiaoping Chen, Zhibin Liao, Furong Liu, Zhanguo Zhang +7 morewiley +1 more sourceEfficacy and Safety of Prophylaxis With a Plasma‐Derived von Willebrand Factor/Factor VIII Concentrate (Wilate) in Patients With Type 3 von Willebrand Disease—A WIL‐31 Study Sub‐Analysis
European Journal of Haematology, Volume 116, Issue 5, Page 674-681, May 2026.ABSTRACT Objectives
The WIL‐31 study demonstrated efficacy and safety of prophylaxis with the plasma‐derived von Willebrand factor/factor VIII concentrate wilate in von Willebrand disease (VWD) of all types and was the only prospective study with an on‐demand run‐in study as an intra‐individual comparator.Claudia Djambas Khayat, Leonid Dubey, Adlette Inati, Toshko Lissitchkov, Dzmitry Novik, Elina Peteva, Robert F. Sidonio Jr, Ali T. Taher, Kateryna V. Vilchevska, Vladimir Vdovin, Ana Boban +10 morewiley +1 more sourceGuidance for Documentation of Therapeutic Apheresis Interventions in the Medical Record: An American Society for Apheresis (ASFA) Practice Perspective
Journal of Clinical Apheresis, Volume 41, Issue 2, April 2026.ABSTRACT
In 2007, the American Society for Apheresis (ASFA) published guidance for physician documentation related to oversight of therapeutic apheresis (TA). Due to 21st century changes in healthcare delivery, the ASFA Board of Directors (BOD) charged its Public Affairs and Advocacy Committee (PAAC) to coordinate a review and update of the guidance ...Chester Andrzejewski, Yanhua Li, Ding Wen Wu, Gustaaf De Ridder, Jan C. Hofmann, Susan Knight, Sajjad Hassan, Nicole A. Aqui, Walter Linz +8 morewiley +1 more sourceImplementation of third-generation digital PCR for non-invasive prenatal diagnosis of sickle cell disease and early detection. Pilot study
Frontiers in MedicineSickle cell disease (SCD) is one of the most prevalent autosomal recessive conditions worldwide, affecting more than 600,000 newborns annually. Despite advances in treatment, it remains a chronic condition requiring lifelong management.Sara Ferrer Benito, Sara Ferrer Benito, Miguel Gómez Álvarez, Miguel Gómez Álvarez, María Josefa Torrejón Martínez, Montserrat López Rubio, Rafael Andrés del Orbe Barreto, Jaime Arbeteta Juanis, María Josefa Muruzabal Siges, Eduardo José Salido Fiérrez, Aránzazu García Mateo, Valle Recasens, Jorge Martínez Nieto, Jorge Martínez Nieto, Ana Villegas Martínez, Fernando Ataúlfo González Fernández, Fernando Ataúlfo González Fernández, Ana Belén Ortega Montero, Laura García Moreno, Paloma Ropero Gradilla, Paloma Ropero Gradilla, Celina Benavente Cuesta, Celina Benavente Cuesta, Spanish Group of Erythropathology +23 moredoaj +1 more sourceThe association of germline variants with chronic lymphocytic leukemia outcome suggests the implication of novel genes and pathways in clinical evolution
BMC Cancer, 2019 Background Chronic Lymphocytic Leukemia (CLL) is the most frequent lymphoproliferative disorder in western countries and is characterized by a remarkable clinical heterogeneity. During the last decade, multiple genomic studies have identified a myriad of Adrián Mosquera Orgueira, Beatriz Antelo Rodríguez, Natalia Alonso Vence, José Ángel Díaz Arias, Nicolás Díaz Varela, Manuel Mateo Pérez Encinas, Catarina Allegue Toscano, Elena María Goiricelaya Seco, Ángel Carracedo Álvarez, José Luis Bello López +9 moredoaj +1 more source