Results 41 to 50 of about 733 (138)

Comparative evaluation of blood component preparation with the top‐and‐top and top‐and‐bottom methods: A change in Uruguay

open access: yesTransfusion Medicine, Volume 36, Issue 3, Page 260-264, June 2026.
Abstract Background Hospital de Clínicas, in conjunction with the Universidad de la República UDELAR in Uruguay, evaluated the quality of blood components after separation with a top‐and‐bottom (TB) system, comparing it with the top‐and‐top (TT) system and verifying compliance with local and international standards. Study Design and Methods Whole blood
Natalia Méndez Acosta   +5 more
wiley   +1 more source

Digital PCR‐based non‐invasive prenatal diagnosis should be considered in the evolving diagnostic pathway for sickle cell disease

open access: yes
HemaSphere, Volume 10, Issue 8, August 2026.
Paloma Ropero   +5 more
wiley   +1 more source

Patient‐ and caregiver‐reported barriers to chemotherapy in nine sub‐Saharan African countries: A cross‐sectional survey among population‐based registries

open access: yesInternational Journal of Cancer, Volume 158, Issue 10, Page 2684-2696, 15 May 2026.
What's New? Increasing cancer incidence and mortality in low‐ and middle‐income countries has heightened concerns about limited resources and barriers to care. This challenge is particularly urgent in Sub‐Saharan Africa (SSA), where cancer rates are rising sharply. Here, data from population‐based cancer registries in nine SSA countries was assessed to
Tamara König   +19 more
wiley   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

open access: yesPediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk   +9 more
wiley   +1 more source

Targeting Tumor Stroma: Current Challenges and Future Directions

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang   +7 more
wiley   +1 more source

Efficacy and Safety of Prophylaxis With a Plasma‐Derived von Willebrand Factor/Factor VIII Concentrate (Wilate) in Patients With Type 3 von Willebrand Disease—A WIL‐31 Study Sub‐Analysis

open access: yesEuropean Journal of Haematology, Volume 116, Issue 5, Page 674-681, May 2026.
ABSTRACT Objectives The WIL‐31 study demonstrated efficacy and safety of prophylaxis with the plasma‐derived von Willebrand factor/factor VIII concentrate wilate in von Willebrand disease (VWD) of all types and was the only prospective study with an on‐demand run‐in study as an intra‐individual comparator.
Claudia Djambas Khayat   +10 more
wiley   +1 more source

Guidance for Documentation of Therapeutic Apheresis Interventions in the Medical Record: An American Society for Apheresis (ASFA) Practice Perspective

open access: yesJournal of Clinical Apheresis, Volume 41, Issue 2, April 2026.
ABSTRACT In 2007, the American Society for Apheresis (ASFA) published guidance for physician documentation related to oversight of therapeutic apheresis (TA). Due to 21st century changes in healthcare delivery, the ASFA Board of Directors (BOD) charged its Public Affairs and Advocacy Committee (PAAC) to coordinate a review and update of the guidance ...
Chester Andrzejewski   +8 more
wiley   +1 more source

Implementation of third-generation digital PCR for non-invasive prenatal diagnosis of sickle cell disease and early detection. Pilot study

open access: yesFrontiers in Medicine
Sickle cell disease (SCD) is one of the most prevalent autosomal recessive conditions worldwide, affecting more than 600,000 newborns annually. Despite advances in treatment, it remains a chronic condition requiring lifelong management.
Sara Ferrer Benito   +23 more
doaj   +1 more source

The association of germline variants with chronic lymphocytic leukemia outcome suggests the implication of novel genes and pathways in clinical evolution

open access: yesBMC Cancer, 2019
Background Chronic Lymphocytic Leukemia (CLL) is the most frequent lymphoproliferative disorder in western countries and is characterized by a remarkable clinical heterogeneity. During the last decade, multiple genomic studies have identified a myriad of
Adrián Mosquera Orgueira   +9 more
doaj   +1 more source

Hemostasis and Hemotherapy [PDF]

open access: yesTransfusion Medicine and Hemotherapy, 2017
Wolfgang, Korte, Marco, Cattaneo
openaire   +2 more sources

Home - About - Disclaimer - Privacy