Results 51 to 60 of about 3,822 (179)
Gene Variants Associated With Venous Thrombosis: A Replication Study in a Brazilian Multicentre Study
Clinical and Applied Thrombosis/Hemostasis, 2020 Single nucleotide polymorphisms (SNP) associated with Venous Thromboembolism (VTE) risk have been identified in European and American populations. Replicate SNPs associated with VTE in a Brazilian multicenter case-control study of the Southeast region ...Anna Virgínia Calazans Romano MSc, Aline Barnabé PhD, Telma Barbosa Gadelha PhD, MD, João Carlos de Campos Guerra PhD, MD, Rodrigo Secolin PhD, Fernanda Loureiro de Andrade Orsi PhD, MD, Gizele de Castro Sousa Campanate PhD, MD, Nelson Wolosker PhD, MD, Joyce Maria Annichino-Bizzacchi PhD, MD +8 moredoaj +1 more sourceMolecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia
Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.ABSTRACT
Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior +9 morewiley +1 more sourceTargeting Tumor Stroma: Current Challenges and Future Directions
MedComm, Volume 7, Issue 5, May 2026.Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).Siwei Wang, Haofan Hu, Weifeng Zeng, Lu Qin, Xiaoping Chen, Zhibin Liao, Furong Liu, Zhanguo Zhang +7 morewiley +1 more sourceEvaluation of the immature platelet fraction contribute to the differential diagnosis of hereditary, immune and other acquired thrombocytopenias
Scientific Reports, 2017 The differential diagnosis of immune (ITP) and hereditary macrothrombocytopenia (HM) is key to patient management. The immature platelet fraction (IPF) represents the subset of circulating platelets with higher RNA content, and has been shown to ...F. L. B. Ferreira, M. P. Colella, S. S. Medina, C. Costa-Lima, M. M. L. Fiusa, L. N. G. Costa, F. A. Orsi, J. M. Annichino-Bizzacchi, K. Y. Fertrin, M. F. P. Gilberti, M. C. Ozelo, E. V. De Paula +11 moredoaj +1 more sourceEfficacy and Safety of Prophylaxis With a Plasma‐Derived von Willebrand Factor/Factor VIII Concentrate (Wilate) in Patients With Type 3 von Willebrand Disease—A WIL‐31 Study Sub‐Analysis
European Journal of Haematology, Volume 116, Issue 5, Page 674-681, May 2026.ABSTRACT Objectives
The WIL‐31 study demonstrated efficacy and safety of prophylaxis with the plasma‐derived von Willebrand factor/factor VIII concentrate wilate in von Willebrand disease (VWD) of all types and was the only prospective study with an on‐demand run‐in study as an intra‐individual comparator.Claudia Djambas Khayat, Leonid Dubey, Adlette Inati, Toshko Lissitchkov, Dzmitry Novik, Elina Peteva, Robert F. Sidonio Jr, Ali T. Taher, Kateryna V. Vilchevska, Vladimir Vdovin, Ana Boban +10 morewiley +1 more sourceThe role of whole-brain radiotherapy (WBRT) in primary central nervous system lymphoma: is it an alternative to ASCT for consolidation following HD-methotrexate based induction in low-income settings?
Radiation Oncology, 2022 Background Primary central nervous system lymphoma (PCNSL) is a rare and aggressive malignancy. Although potentially curable, its prognosis remains dismal.Luís Alberto de Pádua Covas Lage, Vinícius Araújo Soares, Thales Dalessandro Meneguin, Hebert Fabrício Culler, Cadiele Oliana Reichert, Mayara D’Auria Jacomassi, Diego Gomes Cândido Reis, Maria Cláudia Nogueira Zerbini, Renata de Oliveira Costa, Vanderson Rocha, Juliana Pereira +10 moredoaj +1 more sourceGuidance for Documentation of Therapeutic Apheresis Interventions in the Medical Record: An American Society for Apheresis (ASFA) Practice Perspective
Journal of Clinical Apheresis, Volume 41, Issue 2, April 2026.ABSTRACT
In 2007, the American Society for Apheresis (ASFA) published guidance for physician documentation related to oversight of therapeutic apheresis (TA). Due to 21st century changes in healthcare delivery, the ASFA Board of Directors (BOD) charged its Public Affairs and Advocacy Committee (PAAC) to coordinate a review and update of the guidance ...Chester Andrzejewski, Yanhua Li, Ding Wen Wu, Gustaaf De Ridder, Jan C. Hofmann, Susan Knight, Sajjad Hassan, Nicole A. Aqui, Walter Linz +8 morewiley +1 more sourceEvaluation of the Diagnostic Accuracy of the Quantitative Point‐of‐Care SD Biosensor Standard G6PD Test for Assessment of G6PD Deficiency in Infectious Diseases
International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 440-446, April 2026.ABSTRACT Background
G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.Flavia Regina Medeiros da Silva, Alexandre Gomes Vizzoni, Daniela Mendes‐de‐Almeida, Joanna Bokel, Raquel de Vasconcellos Carvalhaes de Oliveira, André Machado Siqueira, Yasmine Rangel Vieira, Simone da Costa Cruz Silva +7 morewiley +1 more sourceHepatitis C virus and hepatitis B virus in indolent lymphomas: Prospective data from the international observational NF10 study
British Journal of Haematology, Volume 208, Issue 6, Page 2229-2234, June 2026.Luca Arcaini, Michele Merli, Sara Rattotti, Maria Elena Nizzoli, Vittoria Tarantino, Chiara Consoli, Annalisa Talami, Roberta Murru, Marina Deodato, Emanuele Cencini, Francesca Re, Carlo Visco, Guilherme Duffles, Michele Spina, Ombretta Annibali, Alessandro Pulsoni, Andrés J. M. Ferreri, Caterina Stelitano, Elsa Pennese, Marzia Varettoni, Emilia Cappello, Gianmarco Favrin, Martina La Fauci, Luigi Marcheselli, Marco Paulli, Stefano Luminari +25 morewiley +1 more sourceImproved Safety of Nucleic Acid Amplification Technology Combined With Serological Tests for Screening Blood Donors: A Systematic Review and Meta‐Analysis
Reviews in Medical Virology, Volume 36, Issue 2, March 2026.ABSTRACT
No laboratory test performed to date provides an absolute guarantee for detecting infectious agents. Nucleic acid amplification techniques/tests (NAT) associated with serological tests can increase safety and provide greater diagnostic accuracy for patients. We investigated the added safety of NAT technology combined with serological tests for Heloise Skiavine Madeira, Aline Ávila Brustolin, Marcos Elias da Silva Almeida, Maiara Vanusa Guedes Ribeiro, Raul Gomes Aguera, Fernando Américo Jorge, Luciana Dias Ghiraldi, Débora de Castro Moreira, Maria Valdrinez Campana Lonardoni, Dennis Armando Bertolini, Leyde Daiane de Peder, Claudinei Mesquita da Silva, Daniele Stéfanie Sara Lopes Lera‐Nonose, Áquila Carolina Fernandes Herculano Ramos‐Milaré, Jorge Juarez Vieira Teixeira +14 morewiley +1 more source