Results 111 to 120 of about 18,226 (260)

Analytical Approaches to Address Challenges in the Analysis of Cannabinoids in Vascular Matrices Using Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud, Robert B. Laprairie, Anas El‐Aneed   +2 more
wiley   +1 more source

Continuous Intrajejunal Levodopa–Carbidopa Infusion in Parkinson's Disease Associated with 22q11.2 Deletion Syndrome: A Case Series

Movement Disorders Clinical Practice, EarlyView.
Abstract Background 22q11.2 deletion syndrome (22q11DS) is a multisystem genetic disorder associated with a significantly increased risk of early‐onset Parkinson's disease (EOPD). Management is challenging because psychiatric and cognitive comorbidities often limit advanced therapies such as deep brain stimulation (DBS). Cases We report 2 patients with
Valle Victor Andrés, Jardel Amory, Hopes Lucie, Clément Guillemette, Lambert Laetitia, Becker Aurélie, Dexheimer Mylène, Bonnet Céline, Frismand Solène, Renaud Mathilde, Puisieux Salomé   +10 more
wiley   +1 more source

Impacts of irrigation system, irrigation rate, and cultivar on hemp production in the semiarid Intermountain West

Agrosystems, Geosciences & Environment
The industrial hemp (Cannabis sativa L.) industry rapidly emerged in Utah in 2019 with nearly 480 ha of production. Production declined rapidly due to flooded floral hemp markets, but the industry is still viable in the state.
Tina Sullivan, Matt Yost, Dakota Boren, Burdette Barker, Earl Creech, Bruce Bugbee   +5 more
doaj   +1 more source

Cannabis‐Based Oil for Pain and Other Non‐Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

Movement Disorders, EarlyView.
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota, Jacy B. Parmera, Matheus Deltreggia, Pedro N. Martins, Anna Letícia M. Alves, Ananda C.M. de Falcone, Ana Rosa Santana, Maria Alice P. Falcão, Mayara A. Dias, Larissa I. Moreira, Paulo C. de Fonseca Filho, Eberval G. Figueiredo, Egberto R. Barbosa, Rubens G. Cury, Daniel C. de Andrade   +14 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

ANALYSIS OF FARMERS' HEMP GROWING TENDENCIES AND EXPECTATIONS: THE CASE OF TÜRKİYE [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development
The purpose of this study is to analyze the factors affecting the tendency of farmers to grow hemp in Rize province of Türkiye. The data was collected by face-to-face survey method from 90 farmers with proportional sampling. A five-point Likert scale was
Esra YAZICI, Sait ENGINDENIZ, Duran GÜLER   +2 more
doaj  

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

The Mediating Role of Disengaged Coping in the Relationship Between Adverse Childhood Experiences and Substance Use Among Sexual Minority Adults

Research in Nursing &Health, EarlyView.
ABSTRACT Adverse childhood experiences (ACEs) are strongly linked to negative long‐term health outcomes. Sexual minority (SM) individuals face disproportionate exposure to ACEs and their consequences compared to heterosexual peers. However, the mechanisms connecting ACEs to these outcomes remain poorly understood.
Marvin A. Schilt‐Solberg, Julie J. A. M. J. Kurzer   +1 more
wiley   +1 more source

Mechanical Performance Retention of CNT‐Modified Sisal Biocomposites Under Hygrothermal‐Saline Aging

Polymer Composites, EarlyView.
Mechanical Performance Retention of CNT‐Modified Sisal Biocomposites Under Hygrothermal‐Saline Aging. ABSTRACT This study investigates the influence of carbon nanotubes (CNTs) on the moisture absorption kinetics and mechanical degradation of discontinuous random fiber (DRF) biocomposites under accelerated hygrothermal–saline (HTS) aging.
Guglielmo Marchesa, Nicola Montinaro, Giuseppe Napoli, Antonio Pantano   +3 more
wiley   +1 more source

Mechanical Properties of Hybrid Natural Fiber–Carbon Fiber‐Reinforced Polypropylene Nonwoven Composites: Influence of Degree of Densification, Fiber Volume Fraction and Laminate Architecture

Polymer Composites, EarlyView.
Reinforcement where it matters: from a homogenious fiber‐reinforced part to a load‐adapted hybrid molded composite part. ABSTRACT Nonwoven composites based on flax fiber (NF)‐reinforced polypropylene (PP) offer a promising route toward sustainable lightweight structures but are limited by moderate mechanical performance.
Florian Tautenhain, Benji Mojzes, Marcus Hartenstein, Roman Rinberg, Lothar Kroll   +4 more
wiley   +1 more source