Results 81 to 90 of about 18,226 (260)

Modifiable Transdiagnostic Risk and Protective Factors as Potential CBT Augmentation Targets for Eating Disorders: An Updated Umbrella Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective A focus on transdiagnostic targets is one of the key strategies for developing effective, efficient, and scalable treatments for mental health conditions. We conducted an umbrella review of recent meta‐analyses (August 2022 to May 2026) to update our understanding of critical transdiagnostic intervention targets that could inform ...
Yuan Zhou, Marcela Radunz, Tracey D. Wade   +2 more
wiley   +1 more source

Efficient Synthesis of Cannabinoid Acids

European Journal of Organic Chemistry, EarlyView.
In this study, an alternative synthesis of cannabinoid acids was developed based on an O→C acyl rearrangement. Specifically, this strategy involved regioselective bromination followed by halogen–lithium exchange and intramolecular nucleophilic addition, which led to successful carboxylation.
Ryosuke Arai, Hikari Nishiguchi, Kayo Nakamura, Hiroko Abe, Akihiko Ishida, Manabu Tokeshi, Kyohei Higashi, Akiyoshi Saitoh, Hideyo Takahashi   +8 more
wiley   +1 more source

Frequent cannabis use and the association with seizure burden in drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective Cannabis use has increased substantially, with modern products characterized by high tetrahydrocannabinol concentrations and variable composition. The relationship between frequent cannabis use and epilepsy outcomes remains uncertain. We examined the association between frequent cannabis use and epilepsy severity, clinical phenotype,
Santiago Philibert‐Rosas, Kaitlin A. Guston, Mariel Kalkach‐Aparicio, Abigail Keller, Sanaa Semia, Theodore Imhoff‐Smith, Cameron J. Brace, Steven E. Haworth, Felipe Branco de Paiva, Dace Almane, Jonathan Williams, Anne Josiah, Bradley Nix, Bruce P. Hermann, Nagesh Adluru, Jana E. Jones, Aaron F. Struck   +16 more
wiley   +1 more source

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source

Green degumming of industrial hemp fibers: Property enhancement and application in hemp/cotton blended yarns

Industrial Crops and Products
Waste fibers generated during hemp fiber processing (hemp noil) are often disposed of as solid waste due to inadequate treatment technologies, causing resource waste and failing to meet the demand for high-quality fibers in yarn production.
Ying Sun, Jiayi Wang, Yucan Jia, Duanxin Li, Dan Sun, Junling Yang   +5 more
doaj   +1 more source

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout, Joseph Sullivan, Stéphane Auvin, J. Helen Cross, Orrin Devinsky, Antonio Gil‐Nagel, Renzo Guerrini, Kelly G. Knupp, M. Scott Perry, Rocío Sánchez‐Carpintero, An‐Sofie Schoonjans, Ingrid E. Scheffer, Nicola Specchio, Adam Strzelczyk, James Wheless, Elaine C. Wirrell, Diego Morita, Patrick Healy, Mélanie Langlois, Amélie Lothe, Lieven Lagae   +20 more
wiley   +1 more source

Neurometabolite abnormalities and associations with epilepsy duration and cognition in patients with idiopathic generalized epilepsies

Epilepsia Open, EarlyView.
Abstract Objective This study investigated whether idiopathic generalized epilepsies (IGEs) are associated with neuroinflammation by measuring neurometabolite levels and brain temperature using whole‐brain magnetic resonance spectroscopy imaging (MRSI).
Yun Lien, Christina Bankston, Ayushe A. Sharma, Brandon S. Mitchell, Rodolphe Nenert, Anna Moyana, Jennifer Pilkington, Roy C. Martin, Charity J. Morgan, Lawrence Ver Hoef, Jerzy P. Szaflarski, Jane B. Allendorfer   +11 more
wiley   +1 more source

First-year hemp farmers’ motives and resources to cultivate hemp

Journal of Agriculture, Food Systems, and Community Development
Recent legislative changes have opened new ave­nues of hemp production for farmers seeking to diversify their operations. With the availability of these opportunities comes the need to better understand the decision making processes of new hemp growers.
Blake Colclasure, Jason Caldwell, Tyler Granberry, Christine Rost, Bailey Gasseling   +4 more
doaj   +1 more source

Alternative protein sources: Extraction, modification and strategies for developing sustainable high‐quality food products

Food Biomacromolecules, EarlyView.
Novel Protein Sources: Strategies and Challenges for Product Formulation Abstract Search for alternative protein sources has intensified in the recent years, owing to the increasing population, demand for sustainable food systems and consumer's shift towards healthier diet choices.
Prem Sankaran, Baskaran Nagarethinam, Sunil Chikkaballapur Krishnappa, Chandrasekar Veerapandian, Ashish Rawson   +4 more
wiley   +1 more source

Building a resilient organic hemp industry: Survey and focus groups assess research, extension, and education needs

Agrosystems, Geosciences & Environment
Hemp (Cannabis sativa L.) has many potential uses, including in textiles, construction, human food, animal feed, health, and personal care applications, and was once widely grown in the United States.
Virginia Moore, Emily Fratz, David Baltensperger, Shelby Ellison, Heather Grab, Lynn Sosnoskie, David Suchoff, Daniela Vergara   +7 more
doaj   +1 more source