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Transmission of henipaviruses [PDF]

open access: yesCurrent Opinion in Virology, 2018
The genus Henipavirus has expanded rapidly in geographic range, number of species, and host range. Hendra and Nipah virus are two henipaviruses known to cause severe disease in humans with a high case-fatality rate. Pteropid spp. bats are the natural reservoir of Hendra and Nipah virus.
Heinrich Feldmann, Emmie de Wit
exaly   +3 more sources

Changing resource landscapes and spillover of henipaviruses

open access: yesAnnals of the New York Academy of Sciences, 2018
AbstractOld World fruit bats (Chiroptera: Pteropodidae) provide critical pollination and seed dispersal services to forest ecosystems across Africa, Asia, and Australia. In each of these regions, pteropodids have been identified as natural reservoir hosts for henipaviruses.
Maureen K Kessler   +2 more
exaly   +5 more sources
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The changing face of the henipaviruses

Veterinary Microbiology, 2013
The Henipavirus genus represents a group of paramyxoviruses that are some of the deadliest of known human and veterinary pathogens. Hendra and Nipah viruses are zoonotic pathogens that can cause respiratory and encephalitic illness in humans with mortality rates that exceed 70%.
Emma L, Croser, Glenn A, Marsh
openaire   +2 more sources

Henipaviruses—unanswered questions of lethal zoonoses

Current Opinion in Virology, 2011
The highly lethal Hendra and Nipah viruses have been described for little more than a decade, yet within that time have been aetiologically associated with major livestock and human health impacts, albeit on a limited scale. Do these emerging pathogens pose a broader threat, or are they inconsequential 'viral chatter'.
Field, Hume, Kung, Nina
openaire   +3 more sources

4′-Azidocytidine (R1479) inhibits henipaviruses and other paramyxoviruses with high potency [PDF]

open access: yesAntiviral Research, 2017
The henipaviruses Nipah virus and Hendra virus are highly pathogenic zoonotic paramyxoviruses which have caused fatal outbreaks of encephalitis and respiratory disease in humans. Despite the availability of a licensed equine Hendra virus vaccine and a neutralizing monoclonal antibody shown to be efficacious against henipavirus infections in non-human ...
Anne L Hotard, Biao He, Michael K Lo
exaly   +3 more sources

Molecular Virology of the Henipaviruses

2012
Nipah (NiV) and Hendra (HeV) viruses comprise the genus Henipavirus and are highly pathogenic paramyxoviruses, which cause fatal encephalitis and respiratory disease in humans. Since their respective initial outbreaks in 1998 and 1994, they have continued to cause sporadic outbreaks resulting in fatal disease.
Paul A, Rota, Michael K, Lo
openaire   +2 more sources

Henipaviruses in Their Natural Animal Hosts

2012
Hendra virus (HeV) and Nipah virus (NiV) form a separate genus Henipavirus within the family Paramyxoviridae, and are classified as biosafety level 4 pathogens due to their high case fatality rate following human infection and because of the lack of effective vaccines or therapy.
D J, Middleton, H M, Weingartl
openaire   +2 more sources

Epidemiology of Henipaviruses

2015
The natural reservoir of Hendra and Nipah virus are fruit bats of the genus Pteropus. In Queensland Australia several people were infected with Hendra virus after close contact with Hendra virus infected horses. In the large outbreak in Malaysia, where Nipah virus (NiV) was first identified, most human infections resulted from close contact with NiV ...
Stephen Luby, Emily Gurley
openaire   +1 more source

Henipaviruses: A new family of emerging Paramyxoviruses

Pathologie Et Biologie, 2009
Paramyxoviruses have been implicated in both animal and human infections. Some viruses, such as Morbilliviruses are responsible for large-scale epidemics. However, there are limited observations of these viruses crossing the host species barrier in nature. In 1994, in Australia a fatal infection in horses and humans was identified to be caused by a new
exaly   +3 more sources

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