Results 151 to 160 of about 2,019 (169)

Henipaviruses: A new family of emerging Paramyxoviruses

Pathologie Et Biologie, 2009
Paramyxoviruses have been implicated in both animal and human infections. Some viruses, such as Morbilliviruses are responsible for large-scale epidemics. However, there are limited observations of these viruses crossing the host species barrier in nature. In 1994, in Australia a fatal infection in horses and humans was identified to be caused by a new
exaly   +3 more sources

Henipaviruses—unanswered questions of lethal zoonoses

Current Opinion in Virology, 2011
The highly lethal Hendra and Nipah viruses have been described for little more than a decade, yet within that time have been aetiologically associated with major livestock and human health impacts, albeit on a limited scale. Do these emerging pathogens pose a broader threat, or are they inconsequential 'viral chatter'.
Field, Hume, Kung, Nina
openaire   +3 more sources

Henipaviruses in Their Natural Animal Hosts

2012
Hendra virus (HeV) and Nipah virus (NiV) form a separate genus Henipavirus within the family Paramyxoviridae, and are classified as biosafety level 4 pathogens due to their high case fatality rate following human infection and because of the lack of effective vaccines or therapy.
D J, Middleton, H M, Weingartl
openaire   +2 more sources

In Vitro Antiviral Screening for Henipaviruses at BSL4

2023
In vitro screening for antivirals is an essential step in the development of effective treatments against new and emerging pathogens. Here, we describe a simple, cell-based screening assay for evaluating antiviral effectiveness against Hendra and Nipah live virus infection under BSL4 conditions.
openaire   +2 more sources

Bats and Emerging Zoonoses: Henipaviruses and SARS

Zoonoses and Public Health, 2009
SummaryNearly 75% of all emerging infectious diseases (EIDs) that impact or threaten human health are zoonotic. The majority have spilled from wildlife reservoirs, either directly to humans or via domestic animals. The emergence of many can be attributed to predisposing factors such as global travel, trade, agricultural expansion, deforestation/habitat
openaire   +3 more sources

Henipaviruses: Gaps in the Knowledge of Emergence

EcoHealth, 2004
(Uploaded by Plazi for the Bat Literature Project) Over the past 10 years many ''new'' viruses have been identified in Australia and the Asian region. The viruses have been isolated from, and/or identified in, a range of animals; some of these viruses are of veterinary and medical importance while others are new threats to biodiversity.
Hyatt, Alex D., Daszak, Peter, Cunningham, Andrew A., Field, Hume, Gould, Allan R.   +4 more
openaire   +1 more source

Henipaviruses: An Updated Review Focusing on the Pteropid Reservoir and Features of Transmission

Zoonoses and Public Health, 2012
SummaryThe henipaviruses, Hendra virus and Nipah virus, are pathogens that have emerged from flying foxes in Australia and South‐east Asia to infect both livestock and humans, often fatally. Since the emergence of Hendra virus in Australia in 1994 and the identification of Australian flying foxes as hosts to this virus, our appreciation of bats as ...
B A, Clayton, L F, Wang, G A, Marsh
openaire   +3 more sources

Utilizing Recombinant Reporter Henipaviruses to Conduct Antiviral Screening

2023
Spillovers of Nipah virus (NiV) from its pteropid bat reservoir into the human population continue to cause near-annual outbreaks of fatal encephalitis and respiratory disease in Bangladesh and India since its emergence in Malaysia over 20 years ago.
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Henipaviruses are Not Yet History

Future Virology, 2015
ABSTRACT  Within the Paramyxoviridae family, Henipaviruses are the deadliest human pathogens. Nipah and Hendra viruses comprise the genus Henipavirus, zoonotic pathogens which cause encephalitis and respiratory disease in humans with mortality rates that can exceed 70%.
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Neuropathogenesis of the henipaviruses in the mouse

Henipaviruses, Hendra virus (HeV) and Nipah virus (NiV), are zoonotic and highly pathogenic to a range of animals including humans. High fatality rates and a lack of vaccines and therapeutics restricts these viruses to the highest biosafety containment in the world.
openaire   +1 more source