Results 151 to 160 of about 1,925 (167)

Epidemiology of Henipaviruses

2015
The natural reservoir of Hendra and Nipah virus are fruit bats of the genus Pteropus. In Queensland Australia several people were infected with Hendra virus after close contact with Hendra virus infected horses. In the large outbreak in Malaysia, where Nipah virus (NiV) was first identified, most human infections resulted from close contact with NiV ...
Stephen Luby, Emily Gurley
openaire   +1 more source

Henipaviruses in Their Natural Animal Hosts

2012
Hendra virus (HeV) and Nipah virus (NiV) form a separate genus Henipavirus within the family Paramyxoviridae, and are classified as biosafety level 4 pathogens due to their high case fatality rate following human infection and because of the lack of effective vaccines or therapy.
D J, Middleton, H M, Weingartl
openaire   +2 more sources

Henipaviruses—unanswered questions of lethal zoonoses

Current Opinion in Virology, 2011
The highly lethal Hendra and Nipah viruses have been described for little more than a decade, yet within that time have been aetiologically associated with major livestock and human health impacts, albeit on a limited scale. Do these emerging pathogens pose a broader threat, or are they inconsequential 'viral chatter'.
Field, Hume, Kung, Nina
openaire   +3 more sources

In Vitro Antiviral Screening for Henipaviruses at BSL4

2023
In vitro screening for antivirals is an essential step in the development of effective treatments against new and emerging pathogens. Here, we describe a simple, cell-based screening assay for evaluating antiviral effectiveness against Hendra and Nipah live virus infection under BSL4 conditions.
openaire   +2 more sources

Bats and Emerging Zoonoses: Henipaviruses and SARS

Zoonoses and Public Health, 2009
SummaryNearly 75% of all emerging infectious diseases (EIDs) that impact or threaten human health are zoonotic. The majority have spilled from wildlife reservoirs, either directly to humans or via domestic animals. The emergence of many can be attributed to predisposing factors such as global travel, trade, agricultural expansion, deforestation/habitat
openaire   +3 more sources

Henipaviruses: epidemiology, ecology, disease, and the development of vaccines and therapeutics

Clinical Microbiology Reviews
SUMMARY Henipaviruses were first identified 30 years ago and have since been associated with over 30 outbreaks of disease in humans. Highly pathogenic henipaviruses include Hendra virus (HeV) and Nipah virus (NiV), classified as biosafety level 4 pathogens.
Jessica R Spengler, Michael K Lo, Stephen R Welch   +2 more
exaly   +3 more sources

Utilizing Recombinant Reporter Henipaviruses to Conduct Antiviral Screening

2023
Spillovers of Nipah virus (NiV) from its pteropid bat reservoir into the human population continue to cause near-annual outbreaks of fatal encephalitis and respiratory disease in Bangladesh and India since its emergence in Malaysia over 20 years ago.
openaire   +2 more sources

Henipaviruses are Not Yet History

Future Virology, 2015
ABSTRACT  Within the Paramyxoviridae family, Henipaviruses are the deadliest human pathogens. Nipah and Hendra viruses comprise the genus Henipavirus, zoonotic pathogens which cause encephalitis and respiratory disease in humans with mortality rates that can exceed 70%.
openaire   +1 more source

Neuropathogenesis of the henipaviruses in the mouse

Henipaviruses, Hendra virus (HeV) and Nipah virus (NiV), are zoonotic and highly pathogenic to a range of animals including humans. High fatality rates and a lack of vaccines and therapeutics restricts these viruses to the highest biosafety containment in the world.
openaire   +1 more source

Medical countermeasures against henipaviruses: a review and public health perspective

Lancet Infectious Diseases, The, 2022
Raúl Gomez Roman, Neil George Cherian, Amy C Shurtleff   +2 more
exaly