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Internalization of anti-nucleolin antibody into viable HEp-2 cells

Molecular Biology Reports, 1996
Anti-nucleolin antibodies have been detected in patients with systemic connective tissue diseases (SCTD) including systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). In vivo bound autoantibodies to nucleoli of epidermal keratinocytes have been demonstrated in skin from patients with SCTD. In this study, monoclonal antibody to nucleolin (D-
J S, Deng, B, Ballou, J K, Hofmeister
openaire   +2 more sources

HEp-2 cell classification with Vector of Hierarchically Aggregated Residuals

Pattern Recognition, 2017
The presence of Antinuclear Autoantibodies (ANA) in human serum is connected with several autoimmune diseases. Indirect Immunofluorescence (IIF) imaging of human epithelial type-2 cells (HEp-2) is the dominant protocol used for the identification of ANA.
Dimitris Kastaniotis   +4 more
openaire   +1 more source

Deeply Supervised Residual Network for HEp-2 Cell Classification

2018 24th International Conference on Pattern Recognition (ICPR), 2018
To diagnose various autoimmune diseases, the accurate Human Epithelial-2 (HEp-2) cell image classification is a very important step. Automatic classification of HEp-2 cell using microscope image is a highly challenging task due to the strong illumination changes derived from the low contrast of the cells.
Hai Xie   +5 more
openaire   +1 more source

Segmentation Guided HEp-2 Cell Classification with Adversarial Networks

2019 Computing, Communications and IoT Applications (ComComAp), 2019
The analysis of indirect immuno fluorescence (IIF) on human epithelial type 2 (HEp-2) cells is of paramount importance for the autoimmune diseases diagnosis. Essentially, accurate segmentation masks can generate rich boundary information, which is beneficial for improving the performance of the classification task For this reason, this paper proposes a
Hai Xie   +4 more
openaire   +1 more source

The effect of agonists and antagonists on Hep-2 cells.

Biomedical sciences instrumentation, 2005
Androgens may play an important role in promoting the growth of laryngeal carcinomas. The aims of this investigation were to investigate the effects of (testosterone (T) and androstendione (AED)) in the presence of the anti-androgen, spironolactone (S), n Hep-2 cellular proliferation and damage after 24, 48 and 72 hours.
LaToya, Phillips   +3 more
openaire   +1 more source

Image analysis and classification of HEp-2 cells in fluorescent images

Proceedings. Fourteenth International Conference on Pattern Recognition (Cat. No.98EX170), 2002
The kind of cells considered in this application are Hep-2 cells, which get used for the identification of antinuclear autoantibodies (ANA). Hep-2 cells allow recognition of over 30 different nuclear and cytoplasmic patterns, which are given by upwards of 100 different autoantibodies.
openaire   +1 more source

Morphological and Texture Features for HEp-2 Cells Classification

2014 1st Workshop on Pattern Recognition Techniques for Indirect Immunofluorescence Images, 2014
Loris Nanni   +3 more
openaire   +2 more sources

Effects of thermic shock on HEp-2 cells

Journal of Ultrastructure Research, 1980
Javier Cervera, Maria Rosa Montero
openaire   +1 more source

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