Results 51 to 60 of about 29,438 (248)

Copper overload affects copper and iron metabolism in Hep-G2 cells

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2004
Divalent metal transporter #1 (DMT1) is responsible for intestinal nonheme Fe apical uptake. However, DMT1 appears to have an additional function in Cu transport in intestinal cells. Because the liver has an essential role in body Cu homeostasis, we examined the potential involvement of Cu in the regulation of DMT1 expression and activity in Hep-G2 ...
Arredondo, M, Cambiazo, V, Tapia, L, Gonzalez-Aguero, M, Nunez, MT, Uauy, R, Gonzalez, M   +6 more
openaire   +8 more sources

Anti-Metastatic Activity of Tagitinin C from Tithonia diversifolia in a Xenograft Mouse Model of Hepatocellular Carcinoma

Livers, 2022
Sesquiterpenoid tagitinin C, present in Tithonia diversifolia leaves, has been known to have anti-hepatoma properties. Therefore, we investigated the anti-metastatic potential of tagitinin C in xenograft models of hepatocellular carcinoma (HCC).
Chuan-Yi Lin, May-Hua Liao, Chi-Yu Yang, Chao-Kai Chang, Shih-Mei Hsu, Chi-Long Juang, Hsiao-Chuan Wen   +6 more
doaj   +1 more source

Modulation by geraniol of gene expression involved in lipid metabolism leading to a reduction of serum-cholesterol and triglyceride levels [PDF]

, 2015
Background: Geraniol (G) is a natural isoprenoid present in the essential oils of several aromatic plants, with various biochemical and pharmacologic properties.
Castro, Maria Agustina, Crespo, Rosana, Galle, Marianela Edith, García de Bravo, Margarita, Lacunza, Ezequiel, Montero Villegas, Sandra, Polo, Monica Patricia, Rodenak Kladniew, Boris Emilio   +7 more
core   +2 more sources

Generation of Multilayered 3D Structures of HepG2 Cells Using a Bio-printing Technique

Gut and Liver, 2017
Background/AimsChronic liver disease is a major widespread cause of death, and whole liver transplantation is the only definitive treatment for patients with end-stage liver diseases.
Hyeryeon Jeon, Kyojin Kang, Su A Park, Wan Doo Kim, Seung Sam Paik, Sang-Hun Lee, Jaemin Jeong, Dongho Choi   +7 more
doaj   +1 more source

Antibacterial, antioxidant and anti-proliferative properties and zinc content of five south Portugal herbs [PDF]

, 2017
Context: Crataegus monogyna L. (Rosaceae) (CM), Equisetum telmateia L. (Equisataceae) (ET), Geranium purpureum Vil. (Geraniaceae) (GP), Mentha suaveolens Ehrh. (Lamiaceae) (MS), and Lavandula stoechas L. spp.
Agnieszka Szewczyk, Bauer AW, Camacho-Luis A, Ceyhan N, Fouad M, Harborne JB., Ignat I, Isabel S. Carvalho, Lamaison JL, Malgorzata Tyszka-Czochara, Marek Szlosarczyk, Neagu E, Pawel Pasko, Radojevic ID, Radulović NS, Ricardo Nunes, Singleton VL, Slobodnikova L, Sohretoglu D, Wadhwani T   +19 more
core   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

Advanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou, Isabel B. Hui, Carla Fernandez‐Rico, Marcy Zenobi‐Wong   +3 more
wiley   +1 more source

Cytotoxicity of titanium and silicon dioxide nanoparticles [PDF]

, 2009
Different TiO 2 and SiO 2 nanoparticles have been tested concerning their toxicity on selected mammalian cell lines. Various powders and suspensions, all of which consist of titanium or silicon dioxide nanoparticles have been examined.
Bahnemann, Detlef W., Behrens, Peter, Kasper, Cornelia, Münzer, Simon, Scheper, Thomas, Wagner, Stefanie   +5 more
core   +2 more sources

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Synthesis of new bioisosteric hemiasterlin analogues with extremely high cytotoxicity

, 2014
International audienceIn this article, we report a convenient and efficient method for the synthesis of new simplified derivativesof hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β-unsaturated aryl groupsas Michael acceptor ...
Doan, Duy Tien, Hoang, Thi Phuong, Jean, Mickael, Ngo, Quoc Anh, Nguyen Van, Tuyen, The, Chinh Pham, Thi, Tham Pham, Thi, Thu Ha Nguyen, Thi, Thu Ha Vu, Thi, Tuyet Anh Dang, van de Weghe, Pierre   +10 more
core   +2 more sources

Mitochondrial fusion and Bid-mediated mitochondrial apoptosis are perturbed by alcohol with distinct dependence on its metabolism [PDF]

, 2018
Environmental stressors like ethanol (EtOH) commonly target mitochondria to influence the cell’s fate. Recent literature supports that chronic EtOH exposure suppresses mitochondrial dynamics, central to quality control, and sensitizes mitochondrial ...
Hajnóczky, György, Madesh, Muniswamy, Naghdi, Shamim, Rubin, Emanual, Slovinsky, William S.   +4 more
core   +3 more sources