Results 101 to 110 of about 190,120 (268)
The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]
, 2009 Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
George, Jacob, Struthers, Allan
core +5 more sources
Advanced Science, EarlyView.It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló +2 more
wiley +1 more source
What is the best therapy for superficial thrombophlebitis? [PDF]
, 2004 For proximal saphenous vein thrombosis, anticoagulation is more effective than venous ligation (with or without stripping) in preventing deep venous thrombosis (DVT) and pulmonary embolus (PE) (strength of recommendation [SOR]: C, qualitative systematic ...
Neher, Jon O., Safranek, Sarah
core
cDC1 Subtype‐Specific In Vivo Targeting of Liposomes
Advanced Science, EarlyView.Dendritic cells, particularly the cDC1 subtype, offer a promising target for drug delivery via liposomes due to their pivotal role in immune regulation, allowing for amplified therapeutic responses. Herein, we show an integration of physicochemical characterization and cell experiments to achieve effective in vivo cDC1 targeting through anti‐CLEC9A ...
Maximilian Schaaf +11 more
wiley +1 more source
Treatment of dural sinus thrombosis with low-molecular-weight heparin [PDF]
, 1999 published_or_final_versio
Cheung, RTF, Ho, SL, Mak, W, Tsoi, TH
core
AI‐Driven Acceleration of Fluorescence Probe Discovery
Advanced Science, EarlyView.We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang +18 more
wiley +1 more source
Haematologica, 2007 Background and Objectives Since the impairment of platelet function may cause excess peri-operative bleeding, pre-operative discontinuation of aspirin and heparin bridging are common for cardiac surgery.
Giulia Renda +9 more
doaj +1 more source
Advanced Science, EarlyView.Virucidal polymers serve as effective antivirals by not only inhibiting viruses but also destroying them. Inspired by the chemical properties of mucin‐mimetics, dendronized polyglycerol‐sulfated, mucin‐inspired amphiphilic copolymers (MIACPs) have been developed.
Raju Bej +10 more
wiley +1 more source
Ewolucja leczenia przeciwzakrzepowego – od kleszcza i pijawki do tabletki
Menopause Review, 2010 This study shows short heparin characteristics used in venous thromboembolism. The research history andthe way of selected heparin synthesis are shortly described. The sequence of drugs showed in the study is basedon their chronological introduction into
Wiesława Bednarek +3 more
doaj
All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Advanced Science, EarlyView.Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
wiley +1 more source