Results 81 to 90 of about 190,120 (268)

Risk Factors of Bleeding after Subcutaneous Injection of Low-molecular-weightHeparin in Elderly Patients with Unstable Angina Pectoris and Asthenia

Guoji laonian yixue zazhi
Objective To analyze the risk factors of bleeding after subcutaneous injection of low-molecular-weight heparin in elderly patients with unstable angina pectoris and weakness.
Qi Wu, Meili Ji, Rong Zhang, Danlei Wang, Peipei Xia   +4 more
doaj   +1 more source

Differentiation of parenteral anticoagulants in the prevention and treatment of venous thromboembolism

Thrombosis Journal, 2011
Background The prevention of venous thromboembolism has been identified as a leading priority in hospital safety. Recommended parenteral anticoagulant agents with different indications for the prevention and treatment of venous thromboembolism include ...
Adiguzel Cafer, Fareed Jawed, Thethi Indermohan   +2 more
doaj   +1 more source

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

Advanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui, Jingwei Wang, Xiaoyun Li, Lina Wang, Xuehan Mao, Rui Lyv, Wenqiang Yan, Jingyu Xu, Jieqiong Zhou, Chenxing Du, Shuhui Deng, Mu Hao, Yan Xu, Shuhua Yi, Dehui Zou, Tao Cheng, Xin Gao, Lugui Qiu, Gang An   +18 more
wiley   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

Low molecular weight heparin-induced thrombocytopenia management during hemodialysis and cardiac surgery: a case report and literature review

JA Clinical Reports
Background Heparin-induced thrombocytopenia (HIT) is a serious complication of heparin therapy, including low molecular weight heparins (LMWHs) like dalteparin.
Shuto Takada, Shogo Suzuki, Takahiro Tamura   +2 more
doaj   +1 more source

Best Practice for Administering Low Molecular Weight Heparin (LMWH) Injection: An Evidence-Based Practice Project

Evidence-Based Nursing Research
Context: Anticoagulation with subcutaneous heparin is the most common treatment for thromboembolic illnesses. LMWH is currently the most popular parenteral anticoagulant drug. Low molecular weight heparins are given by subcutaneous injection.
Faisal A. Alasmari, Mohammad A. Hazazi, Ebtisam A. Ebrahim, Mirshad T. Thazha, Daoud A. Alkouz, Hadeel Y. ALhawsawi, Rudayna H. Al Romaili, Thaer W. Almalad   +7 more
doaj   +1 more source

Low Molecular Weight Heparin Overdose: A 10 Year Case Series [PDF]

Asia Pacific Journal of Medical Toxicology, 2013
Background: Low molecular weight heparin (LMWH) is used for the treatment and prevention of coagulative disorders. Few patients receiving therapeutic doses of LMWH develop major hemorrhage.
Adeline Ngo, Daryl Tan, Kent Olson
doaj  

Rational Design of Anticoagulant Drugs Using Oligosaccharide Chemistry

CHIMIA, 2011
For a long time, heparin and low molecular weight heparins have been the drugs of choice for the management of thrombosis. Discovery of the antithrombin binding domain in heparin, a critical element in the anticoagulant activity of this ...
Ahmed El Hadri, Maurice Petitou
doaj   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Development of new heparin-like compounds and other antithrombotic drugs and their interaction with vascular endothelial cells

Brazilian Journal of Medical and Biological Research, 2001
The anticlotting and antithrombotic activities of heparin, heparan sulfate, low molecular weight heparins, heparin and heparin-like compounds from various sources used in clinical practice or under development are briefly reviewed.
H.B. Nader, M.A.S. Pinhal, E.C. Baú, R.A.B. Castro, G.F. Medeiros, S.F. Chavante, E.L. Leite, E.S. Trindade, S.K. Shinjo, H.A.O. Rocha, I.L.S. Tersariol, A. Mendes, C.P. Dietrich   +12 more
doaj   +1 more source