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Management of Heparin-Induced Thrombocytopenia: A Contemporary Review. [PDF]
Ng JY, D'Souza M, Hutani F, Choi P.
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Heparin induced thrombocytopenia-type 2
Majeed Tanveer
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Heparin-induced thrombocytopenia
Hämostaseologie, 2010SummaryHeparin-induced thrombocytopenia (HIT), typically occurring in the second week of heparin therapy, is an antibody-mediated adverse drug reaction associated with increased thrombotic risk. The most important antigens are located on platelet factor 4 (PF4)/heparin complexes.
A, Greinacher +3 more
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Heparin induced thrombocytopenia
BMJ, 2015This clinical review has been developed for The BMJ in collaboration with BMJ Best Practice, based on a regularly updated web/mobile topic that supports evidence based decision making at the point of care. To view the complete and current version, please refer to the heparin induced thrombocytopenia (http://bestpractice.bmj.com/best-practice/monograph ...
Andreas Greinacher
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Heparin-Induced Immune Thrombocytopenia
New England Journal of Medicine, 1976We studied five patients in whom severe thrombocytopenia developed during intermittent intravenous heparin treatment of arterial and venous thrombosis. Platelet aggregation was demonstrated when heparin (0.5 U per milliliter) was incubated with the patients' citrated platelet-rich plasma or with normal platelet-rich plasma in the presence of the ...
R B, Babcock +2 more
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Heparin-Induced Thrombocytopenia
International Anesthesiology Clinics, 2004Heparin is widely used for the prevention and treatment of thrombotic and particularly cardiovascular disorders. Unfortunately, 0.5 to 3.0% of patients given heparin develop an immune reaction, commonly termed Type II heparin-induced thrombocytopenia (HIT).
Mark E, Comunale, Elizabeth M, Van Cott
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Heparin-induced Thrombocytopenia
Pathophysiology of Haemostasis and Thrombosis, 1986Heparin-induced thrombocytopenia is the most frequent and the most important idiosyncratic haematological drug reaction. It is important for several reasons: first, because heparin is used so often, and the frequency of heparin-induced thrombocytopenia is high, the risk of a hospitalized patient developing heparin-induced thrombocytopenia is high ...
J G, Kelton, M N, Levine
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Heparin–induced thrombocytopenia
American Journal of Health-System Pharmacy, 1995Heparin is one of the most frequently prescribed medications in the United States with more than 1 trillion units being used each year. However, some patients who receive heparin may have development of a rare but severe complication called heparin-induced thrombocytopenia, which is associated with significant morbidity and mortality rates.
D A, Borkowski, R W, Force
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HEPARIN‐INDUCED THROMBOCYTOPENIA
BJU International, 2007Each year, 25% of all hospitalized patients are affected by venous thromboembolism, a disease comprising deep vein thrombosis and pulmonary embolism, that is responsible for up to 10% of all inpatient deaths (Alikhan, Peters, Wilmott, Cohen, 2004). Used in both the treatment and the prevention of venous thromboembolism, heparin is administered to more ...
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Heparin-Induced Thrombocytopenia
Australian and New Zealand Journal of Medicine, 1988Abstract:Thrombocytopenia is a common adverse effect of heparin therapy. Two types of heparinlinduced thrombocytopenia (HIT) are observed clinically ‐ an early onset mild thrombocytopenia (Type I) in which the patients remain asymptomatic and a delayed onset severe thrombocytopenia (Type II).
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