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Heparin-Induced Thrombocytopenia
Surgical Clinics of North America, 2012This article deals with heparin-induced thrombocytopenia. It discusses the pathophysiology of the disease, as well as the diagnostic challenges and therapeutic management. The incidence of the disease and screening recommendations are reviewed. The article also emphasizes the importance of correct diagnosis and treatment options.
Stephen, Lanzarotti, John A, Weigelt
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Heparin-Induced Thrombocytopenia
JAMA: The Journal of the American Medical Association, 1979Heparin, a drug responsible for a majority of drug deaths in patients who are reasonably healthy,1still eludes precise definition as to its structural composition.2Derived from mast cells of bovine lung and porcine gut, heparin preparations may vary in purity and antigenic effects.
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Heparin-induced thrombocytopenia
Clinical Toxicology, 2014Abstract A summary of heparin-induced thrombocytopenia (HIT) is presented. HIT is an adverse drug reaction characterized by thrombocytopenia and a high risk for venous or arterial thrombosis. The frequency of HIT ranges from 1 to 5% of patients receiving heparin with exact frequencies ranging between specific agents. Interestingly, this immune-mediated
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Heparin-Induced Thrombotic Thrombocytopenia
Chest, 1981Following subcutaneous therapy with heparin, the patient developed signs and symptoms of vascular occlusion in both legs. This was accompanied by thrombocytopenia and platelet aggregation when the patient's platelets were incubated with heparin. The clinical features and implications of this syndrome are discussed.
G, Hollander +3 more
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Heparin-Induced Thrombotic Thrombocytopenia
Annals of Pharmacotherapy, 1994OBJECTIVE: To report a case of heparin-induced thrombotic thrombocytopenia (HITTS) and discuss the incidence, possible mechanisms, complications, and treatment for this syndrome. DATA SOURCES: Case reports and review articles identified by MEDLINE from 1980 through 1991. Older articles located by manual searches.
D E, Phillips, D K, Payne, G M, Mills
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Heparin-Induced Thrombocytopenia
KardiologiiaThe extensive use of therapeutic doses of heparin to prevent thrombosis in critically ill patients with COVID-19 during the pandemic has led to an increased incidence of bleeding and heparin-induced thrombocytopenia (HIT). In addition, the introduction of the AstraZeneca and Johnson&Johnson vaccines against COVID-19 into clinical practice was ...
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Heparin-induced thrombocytopenia
Current Treatment Options in Cardiovascular Medicine, 2001Treatment with heparin is associated with two types of thrombocytopenia. The most worrisome of these is the immune-mediated heparin-induced thrombocytopenia (HIT type II). Suspicion of HIT type II mandates immediate cessation of heparin administration and consideration of an alternative anticoagulation therapy.
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Heparin-induced thrombocytopenia
Journal of Vascular Nursing, 2000Heparin-induced thrombocytopenia is a rare but complex adverse drug reaction that can produce devastating results. Treatment and clinical management of the patient requires close observation and education of the pathophysiology occurring at the cellular level. Documented cases of heparin-induced thrombocytopenia have been reported in the literature for
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Subcutaneous Heparin-Induced Thrombocytopenia
Archives of Internal Medicine, 1978Two patients developed severe and symptomatic thrombocytopenia which was clearly related to the every-12-hour subcutaneous administration of heparin sodium. One patient died of hemorrhage while the other patient's platelet count normalized after withdrawal of the therapy.
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HIT Heparin-Induced Thrombocytopenia
The Nurse Practitioner, 2011Heparin-induced thrombocytopenia (HIT) is a significant complication of heparin therapy. The NP is in a pivotal position to identify patients at greater risk for HIT and promptly diagnose and intervene to prevent serious thrombotic complications.
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