Results 91 to 100 of about 724,197 (388)

Development and analytical performance evaluation of an automated chemiluminescent immunoassay for pro-gastrin releasing peptide (ProGRP) [PDF]

, 2009
Background: Pro-gastrin releasing peptide ( ProGRP) concentrations in blood play an important role in the diagnosis and treatment of patients with small cell lung cancer (SCLC).
Beligere, Gangamani S., Chan, Daniel W., Chan, Sabrina S., Dowell, Barry L., Elliott, Debra, Fujita, Kenju, Hofmann, Karin, Iizuka, Masayuki, Kinukawa, Hideki, Matsuoka, Yoshiharu, Patil, Rahul D., Saegusa, Haruhisa, Sakurai, Yousuke, Scheuer, Cornelia, Sokoll, Lori, Stieber, Petra, Yamaguchi, Ken, Yoshimura, Toru   +17 more
core   +2 more sources

Heparin-Mimicking Polymers: Synthesis and Biological Applications

Biomacromolecules, 2016
Heparin is a naturally occurring, highly sulfated polysaccharide that plays a critical role in a range of different biological processes. Therapeutically, it is mostly commonly used as an injectable solution as an anticoagulant for a variety of ...
S. Paluck, Thi H. Nguyen, H. Maynard
semanticscholar   +1 more source

Heparin sequencing [PDF]

Glycobiology, 2002
Heparin is a highly sulfated glycosaminoglycan widely used as an anticoagulant. Modifications in its relatively uniform structure appear to be key to its recognition and modulation of serine proteases, growth factors, chemokines, and extracellular proteins, as has been most clearly demonstrated in the antithrombin binding site.
Stringer, Sally E., Kandola, Balbant S., Pye, David A., Gallagher, John T.   +3 more
openaire   +2 more sources

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

A comparison of sequential total and activated white cell count in patients undergoing coronary artery bypass grafting, using cardiopulmonary bypass, with and without a white cell filter

, 1999
Introduction Cardiopulmonary bypass (CPB) has been shown to induce a systemic inflammatory response similar to the local reaction seen after tissue damage [1].
D Johnson, DC Smith, JK Kirklin, JK Nanson, M Kulkarni, PJ Thurlow, SV Sheppard   +6 more
core   +1 more source

A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering

Advanced Healthcare Materials, EarlyView.
In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.
Bowu Peng, Huajian Chen, Chengyu Lu, Tianjiao Zeng, Man Wang, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen   +8 more
wiley   +1 more source

Heparin insolubilized with crosslinking agent [PDF]

, 1969
New plastic compositions, involving the systhesis of a polymeric system containing heparin insolubilized with crosslinking agents, show appreciable promise in human body implant ...
Rembaum, A.
core   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

Heparin-induced thrombocytopenia

Journal of Emergencies, Trauma and Shock, 2011
In the last 7 decades heparin has remained the most commonly used anticoagulant. Its use is increasing, mainly due to the increase in the number of vascular interventions and aging population.
Shaikh Nissar
doaj  

Validation and determination of a reference interval for Canine HbA1c using an immunoturbidimetric assay [PDF]

, 2017
Background: Hemoglobin A1c (HbA1c) provides a reliable measure of glycemic control over 2–3 months in human diabetes mellitus. In dogs, presence of HbA1c has been demonstrated, but there are no validated commercial assays. Objective: The purpose
Goemans, Anne F., Ramsey, Ian K., Spence, Susanna J.   +2 more
core   +1 more source