Results 91 to 100 of about 522,479 (352)

Biofunctionalization of ADA‐GEL Hydrogels Based on the Degree of Cross‐Linking and Polymer Concentration Improves Angiogenesis

Advanced Healthcare Materials, EarlyView.
The biocompatibility of alginate dialdehyde (ADA) and gelatin (GEL) hydrogels cross‐linked with human transglutaminase (hTG) is demonstrated in vivo with a high degree of stability and angiogenic potential. The additional enzymatic cross‐linker hTG and the increased concentration improve stability and angiogenic potential. The X‐ray microscopy (XRM) is
Stefanie Heltmann‐Meyer, Rainer Detsch, Jonas Hazur, Lasse Kling, Sabrina Pechmann, Rajkumar Reddy Kolan, Justus Osterloh, Aldo R. Boccaccini, Silke Christiansen, Carol I. Geppert, Andreas Arkudas, Raymund E. Horch, Dominik Steiner   +12 more
wiley   +1 more source

Modulation of Interleukin-12 activity in the presence of heparin

Scientific Reports, 2017
Glycosaminoglycans (GAGs), especially heparin and heparan sulfate (HS), modulate the functions of numerous cytokines. The aims of this multidisciplinary research were to characterize heparin binding to interleukin-12 (IL-12) and determine the mechanism(s)
Srinivas Jayanthi, Bhanu prasanth Koppolu, Khue G. Nguyen, Sean G. Smith, Barbara K. Felber, Thallapuranam Krishnaswamy Suresh Kumar, David A. Zaharoff   +6 more
doaj   +1 more source

Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period [PDF]

, 2010
Some women are at risk of forming blood clots in a deep vein during pregnancy, after a caesarean birth, or during the first few weeks after childbirth. If part of the clot breaks off and lodges in a blood vessel in the lungs, it can be life-threatening ...
Abou-Nassar, Abou-Nassar, Alfirevic, Alikhan, Andersen, Atrash, Badawy, Barbour, Bates, Blomback, Brenner, Brenner, Brenner, Brenner, Brenner, Brenner, Brill-Edwards, Brocklehurst, Brocklehurst, Brocklehurst, Burrows, Casele, Casele, Chistolini, Cohen, Conard, Connolly, Cornette, Dargaud, Dendrinos, Dittmer, Ellison, Ellison, Ellison, Empson, Farquharson, Friederich, Gates, Gates, Gates, Gherman, Gibson, Hall, Hamersley, Harenberg, Heilman, Heilmann, Heit, Hill, Hill, Howell, Högberg, Kaandorp, Kakkos, Kamin, Knight, Krauss, Kutteh, Kutteh, Larciprete, Letsky, Lewis, Lindhagen, Lindqvist, Macklon, Middeldorp, Nelson-Piercy, Noble, Orme, Paull, Pettila, Pettila, Pomp, Rai, Ramos, Rey, Rey, Rodger, Rodger, Rodger, Rutherford, Segal, Simpson, Stefano, Stephenson, Taylor, Testroote, Thaler, Tulppala, Veciana, Walker, Welti, Wu   +92 more
core   +1 more source

Self‐Healing Hydrogel Dressing with Solubilized Flavonoids for Whole Layer Regeneration of Diabetic Wound

Advanced Healthcare Materials, EarlyView.
High glucose‐ and acid‐responsive hydrogel with dynamic covalent bond solubilized with flavonoids (Gel‐Flavonoids) is designed for diabetic wound healing. The Gel‐Flavonoids adapt to irregular wound shapes and release antioxidants in high‐glucose environments, effectively reducing reactive oxygen species.
Qiang Zeng, Sa Du, Rui Yuan, Yuan Zeng, Xuefen Li, Yu‐Wei Wu, Ke Chen, Lei Tao, Zhihui Tang, Xuliang Deng   +9 more
wiley   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Virus removal from aqueous environments with polyelectrolyte coatings on a polypropylene fleece

Journal of Applied Polymer Science, Volume 140, Issue 6, February 10, 2023., 2023
We present three methods to immobilize heparin‐mimicking, virus‐binding polymers on filter materials. Linear polyglycerol sulfate is grafted to the surface either via mussel‐inspired coating chemistry, or by using a benzophenone anchor. Herpes simplex virus type 1 and severe acute respiratory virus 2 are efficiently removed from solution upon ...
Maiko Schulze, Chuanxiong Nie, Greta Hartmann, Philip Nickl, Michaël W. Kulka, Matthias Ballauff, Rainer Haag   +6 more
wiley   +1 more source

Eliminating Spiked Bovine Spongiform Encephalopathy Agent Activity from Heparin

Emerging Infectious Diseases, 2020
US manufacturers, concerned about bovine spongiform encephalopathy (BSE), ceased marketing bovine heparin in the 1990s. Recent short supplies of safe porcine heparin suggest that reintroducing bovine heparin might benefit public health.
Cyrus Bett, Omozusi Andrews, David M. Asher, Teresa Pilant, David Keire, Luisa Gregori   +5 more
doaj   +1 more source

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Development of a method for measuring blood coagulation using superparamagnetic iron oxide nanoparticles and an alternating magnetic field [PDF]

arXiv, 2016
We developed a method for measuring blood coagulation using superparamagnetic iron oxide nanoparticles (SPIONs) and an alternating magnetic field (AMF). The 3rd and 5th harmonic signals from SPIONs mixed with blood induced by AMF were detected using a gradiometer coil.
arxiv  

Coagulation, fibrinolysis, and cell activation in patients and shed mediastinal blood during coronary artery bypass grafting with a new heparin-coated surface [PDF]

, 2002
Objectives: Heparin coating of the cardiopulmonary bypass circuit is shown to improve the biocompatibility of the surface. We have studied a new heparin surface, the Corline Heparin Surface, applied to a complete set of an extracorporeal device used ...
Johnell, Matilda, Elgue, Graciela, Larsson, Rolf, Larsson, Anders, Thelin, Stefan, Siegbahn, Agneta   +5 more
core   +1 more source