Results 81 to 90 of about 507,262 (350)
Advanced Healthcare Materials, EarlyView.What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu +13 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source
Heparin Interference in the Cerebrospinal Fluid Protein Assay Measured with a Pyrogallol Red-Molybdate Complex [PDF]
, 2011 Background: Increased cerebrospinal fluid (CSF) total protein is a useful indicator of meningeal or central nervous system disease. Occasionally the primary care physicians added heparin to CSF samples to avoid clotting .
楊瑞檥;簡慈儀;呂金盈;高照村 +1 more
core
The use of heparin and heparin-like molecules in cancer treatment: a review
Cancer Treatment and Research Communications, 2020 Background: Heparin and heparin-like molecules have shown some promise in the treatment of several cancers. These molecules have roles in angiogenesis, cell proliferation, immune system modulation, cell migration, and cellular invasion.
Johnny Atallah +3 more
doaj +1 more source
Heparin: Past, Present, and Future
Pharmaceuticals, 2016 Heparin, the most widely used anticoagulant drug in the world today, remains an animal-derived product with the attendant risks of adulteration and contamination.
E. Oduah, R. Linhardt, S. Sharfstein
semanticscholar +1 more source
Advanced Materials, EarlyView.A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu +7 more
wiley +1 more source
The role of heparin in the activation of mast cell tryptase [PDF]
, 2004 Mast cells play an important role in our immune defense against bacteria and parasites but are also key effector cells in various inflammatory diseases. They act by releasing inflammatory mediators from intracellular granules.
Hallgren, Jenny
core
Heparin-Promoted Cellular Uptake of the Cell-Penetrating Glycosaminoglycan Binding Peptide, GBPECP, Depends on a Single Tryptophan [PDF]
, 2016 A 10-residue, glycosaminoglycan-binding peptide, GBPECP, derived from human eosinophil cationic protein has been recently designated as a potent cell-penetrating peptide.
Yi-Lin Hung (707975) +9 more
core +1 more source
Veterinary Medicine and ScienceBackground No guidelines for administering and monitoring anticoagulants intraprocedurally are currently available in dogs, despite the prevalence of procedures necessitating systemic anticoagulation with heparin.
A. Hellemans +7 more
doaj +1 more source