Results 1 to 10 of about 19,040 (169)
Heparin-induced thrombocytopenia [PDF]
Current Medicine Research and Practice, 2021 Heparin-induced thrombocytopenia (HIT) is an adverse prothrombotic disorder caused by an immune response to complexes of platelet factor 4 and polyanions. The clinical relevance of HIT results from the wide use of heparin, which is the reason that the absolute number of patients affected by HIT is high.
Prakash Shastri, Shubhlesh Kumar
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Performance evaluation of a reflexive algorithm for suspected heparin-induced thrombocytopenia [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: The diagnostic workup of heparin-induced thrombocytopenia (HIT) involves a heparin–platelet factor 4 complex-dependent screening test, such as an enzyme-linked immunosorbent assay (ELISA) or a rapid latex immunoturbidimetric assay (LIA ...
Sean G. Yates +6 more
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Heparin-induced thrombocytopenia
Journal of Emergencies, Trauma and Shock, 2011 In the last 7 decades heparin has remained the most commonly used anticoagulant. Its use is increasing, mainly due to the increase in the number of vascular interventions and aging population.
Shaikh Nissar
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Heparin-induced thrombocytopenia: an update [PDF]
Thrombosis Journal, 2005 Heparin-induced thrombocytopenia (HIT) is the most important and most frequent drug-induced, immune-mediated type of thrombocytopenia. It is associated with significant morbidity and mortality if unrecognized.
Franchini Massimo
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HEPARIN INDUCED THROMBOCYTOPENIA
Zdravniški Vestnik, 2008 BACKGROUND Unfractionated heparin and low-molecular-weight-heparins are commonly prescribed drugsin everyday clinical practice for treatment or prevention of thrombotic diseases. Heparinis used also for providing patency of various catheters.
Matija Kozak +2 more
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Heparin-induced thrombocytopenia
Haematologica, 2000 BACKGROUND AND OBJECTIVE: There are two types of heparin-induced thrombocytopenia (HIT). HIT I is characterized by a transitory, slight and asymptomatic reduction in platelet count, occurring in the first 1-2 days of therapy, that resolves spontaneously;
F Fabris +5 more
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Heparin-Induced Thrombocytopenia [PDF]
Circulation, 2006 Heparin-induced thrombocytopenia (HIT) is an immune-mediated hypercoagulable disorder caused by antibodies to platelet factor 4 (PF4) and heparin. HIT develops in temporal association with heparin therapy and manifests either as an unexplained thrombocytopenia or thrombocytopenia complicated by thrombosis.
Steven A, Baroletti, Samuel Z, Goldhaber
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Heparin-Induced Thrombocytopenia
Annual Review of Medicine, 1989 Heparin-induced thrombocytopenia (HIT) is an immune-mediated adverse drug effect that is characterized by platelet activation, hypercoagulability, and a resulting increased risk for thrombosis, both venous and arterial. This disorder is autoimmune-like, because the target antigen is a multimolecular complex of the "self" protein, platelet factor 4, and
T E, Warkentin, J G, Kelton
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Emergency and Critical Care Medicine, 2023 . Background. Thrombocytopenia commonly occurs early after liver transplantation. Heparin, usually administered as anticoagulant therapy for thrombosis, a common complication after liver transplantation, may cause heparin-induced thrombocytopenia ...
Naoya Iwasaki +13 more
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Heparin-Induced Thrombocytopenia [PDF]
New England Journal of Medicine, 1997 Heparin-induced thrombocytopenia (HIT), typically occurring in the second week of heparin therapy, is an antibody-mediated adverse drug reaction associated with increased thrombotic risk. The most important antigens are located on platelet factor 4 (PF4)/heparin complexes.
Naomi B, Klarenbeek +1 more
openaire +7 more sources