Results 61 to 70 of about 374,140 (284)

Amphiphilic glycopolymers and glycopeptides. properties and applications [PDF]

open access: yes, 2008
In this thesis, the properties and potential application fields of saccharide-based block copolymers are explored. The anionic polysaccharide heparin was coupled to hydrophobic blocks – poly(dimethyl siloxane) (PDMS) and poly (ethyl ethylene) (PEE ...
Sebök, Diana
core   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

open access: yesAdvanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li   +9 more
wiley   +1 more source

Characterization of PmHS2 glycosyltransferases for the controlled synthesis of heparosan : a precursor of heparin and heparan sulfate [PDF]

open access: yes, 2011
Heparin (Hep), a highly sulfated and complex glycosaminoglycan polysaccharides, is worldwide used as an anticoagulant compound to prevent blood clotting during surgery.
Chavaroche, A.A.E.
core  

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs

open access: yesAdvanced Materials, EarlyView.
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum   +14 more
wiley   +1 more source

Modulation of Interleukin-12 activity in the presence of heparin

open access: yesScientific Reports, 2017
Glycosaminoglycans (GAGs), especially heparin and heparan sulfate (HS), modulate the functions of numerous cytokines. The aims of this multidisciplinary research were to characterize heparin binding to interleukin-12 (IL-12) and determine the mechanism(s)
Srinivas Jayanthi   +6 more
doaj   +1 more source

A véralvadásgátló, heparin-analóg fondaparinux szintézisének lehetőségei

open access: yes, 2021
A szervezetben a véralvadás egy igen fontos biokémiai folyamat akár külső sérülés, akár belső bakteriális hatás esetén is. A véralvadás kaszkád első lépésénél ható heparin és származékainak tulajdonsága, hogy negatív felületet biztosítanak az alvadás ...
Pap, Gergely
core  

Lab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile Infection

open access: yesAdvanced Materials, EarlyView.
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena   +10 more
wiley   +1 more source

The anti-cancer properties of heparin and its derivatives: a review and prospect

open access: yesCell Adhesion & Migration, 2020
Heparin, including unfractionated heparin (UFH), low-molecular-weight heparin (LMWH) and heparin derivatives, are commonly used in venous thromboembolism treatment and reportedly have beneficial effects on cancer survival.
Sai-Nan Ma   +8 more
doaj   +1 more source

The mitogenic potential of heparin-binding epidermal growth factor in the human endometrium is mediated by the epidermal growth factor receptor and is modulated by tumor necrosis factor-alpha [PDF]

open access: yes, 2002
Heparin-binding epidermal growth factor (HB-EGF), a member of the epidermal growth factor (EGF) family, is implicated in a variety of biological processes, including reproduction.
Mardon, Helen J.   +23 more
core   +1 more source

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