Results 41 to 50 of about 380,856 (149)

Heparin-Induced Hyperkalemia Assessment Utilizing the Naranjo Adverse Drug Reaction Probability Scale: A 40-Year Systematic Review

Pharmacy
Background: Adverse drug reactions have been reported as leading causes of morbidity and mortality. Unfractionated heparin- and low-molecular-weight heparin-induced hyperkalemia are side effects that have been reported in approximately 7 to 8% of heparin-
Divita Singh, Omnia A. E. A. Mesalhy, Michael J. Cawley   +2 more
doaj   +1 more source

Characterization of PmHS2 glycosyltransferases for the controlled synthesis of heparosan : a precursor of heparin and heparan sulfate [PDF]

, 2011
Heparin (Hep), a highly sulfated and complex glycosaminoglycan polysaccharides, is worldwide used as an anticoagulant compound to prevent blood clotting during surgery.
Chavaroche, A.A.E.
core  

Effect of Heparin on Coagulation Tests: A Comparison of Continuous and Bolus Infusion in Haemodialysis Patients [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Haemodialysis is one of the most conventional treatments of chronic renal failure. The risk of clot formation is high during haemodialysis due to regular contact of blood with the surfaces of foreign objects such as catheters, dialyzers’
Ali Akbar Nasiri, Sudabeh Ahmadidarrehsima, Abbas Balouchi, Hosein Shahdadi, Mahdiye Poodine Moghadam   +4 more
doaj   +1 more source

Evaluation of the use of a heparin dose‐response test in dogs to determine the optimal heparin dose during intravascular procedures and assessment of the in vitro heparin response in healthy dogs

Veterinary Medicine and Science
Background No guidelines for administering and monitoring anticoagulants intraprocedurally are currently available in dogs, despite the prevalence of procedures necessitating systemic anticoagulation with heparin.
A. Hellemans, N. Devriendt, L. Duchateau, K. M. J. Devreese, F. De Somer, T. Bosmans, G. Mampaey, P. Smets   +7 more
doaj   +1 more source

The use of heparin and heparin-like molecules in cancer treatment: a review

Cancer Treatment and Research Communications, 2020
Background: Heparin and heparin-like molecules have shown some promise in the treatment of several cancers. These molecules have roles in angiogenesis, cell proliferation, immune system modulation, cell migration, and cellular invasion.
Johnny Atallah, Hussein H. Khachfe, Juliett Berro, Hazem I. Assi   +3 more
doaj   +1 more source

Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants

Molecules, 2019
Nowadays, pharmaceutical heparin is purified from porcine and bovine intestinal mucosa. In the past decade there has been an ongoing concern about the safety of heparin, since in 2008, adverse effects associated with the presence of an oversulfated ...
Aline Mendes, Maria C. Z. Meneghetti, Marcelly Valle Palladino, Giselle Zenker Justo, Guilherme L. Sassaki, Jawed Fareed, Marcelo A. Lima, Helena B. Nader   +7 more
doaj   +1 more source

Effect of Non-Anticoagulant N-Desulfated Heparin on Basic Fibroblast Growth Factor Expression, Angiogenesis, and Metastasis of Gastric Carcinoma In Vitro and In Vivo

Gastroenterology Research and Practice, 2012
Objective. The present study was performed to investigate the effect of N-desulfated heparin on basic fibroblast growth factor (bFGF) expression, tumor angiogenesis and metastasis of gastric carcinoma. Methods.
Jin-Lian Chen, Jing Fan, Ming-Xiang Chen, Ying Dong, Jian-Zhong Gu   +4 more
doaj   +1 more source

Spontaneous heparin-induced thrombocytopenia presenting as bilateral adrenal hemorrhages and pulmonary embolism after total knee arthroplasty

Arthroplasty Today, 2015
Heparin-induced thrombocytopenia syndrome is an acquired potentially life-threatening prothrombotic disorder caused by antibodies that recognize complexes of platelet factor 4 bound to heparin or heparin-like molecules. It typically occurs after exposure
Amro Elshoury, MBChB, Maha Khedr, MBChB, Mostafa M. Abousayed, MD, Syed Mehdi, MD   +3 more
doaj   +1 more source

Heparin-Coated Photosensitive MetalOrganic Frameworks as Drug Delivery Nanoplatforms of Autophagy Inhibitors for Sensitized Photodynamic Therapy against Breast Cancer

, 2021
Photosensitive nanosized metal–organic frameworks (nanoMOFs) with a tunable structure and high porosity have been developed recently as nanophotosensitizers (nanoPSs) for photodynamic therapy (PDT).
Mengmeng Zhang (1507543), Ye Yang (297214), Quanwei Sun, Ye Yang, Mengmeng Zhang, Jinming Yang (366356), Dengke Yin, Yang Liu (4829), Jinming Yang, Yang Liu, Wei Shen (149127), Wei Shen, Quanwei Sun (8495739), Xiaohui Hou, Dengke Yin (6237086), Xiaohui Hou (2517832)   +15 more
core   +1 more source

Conserved Surface-Exposed K/R-X-K/R Motifs and Net Positive Charge on Poxvirus Complement Control Proteins Serve as Putative Heparin Binding Sites and Contribute to Inhibition of Molecular Interactions with Human Endothelial Cells: a Novel Mechanism for Evasion of Host Defense [PDF]

, 2000
Vaccinia virus complement control protein (VCP) has been shown to possess the ability to inhibit both classical and alternative complement pathway activation.
Shchelkunov, SN, Reynolds, DN, Kotwal, GJ, Justus, DE, Srisatjaluk, R, Loparev, VN, Totmenin, AV, Keeling, KL, Smith, SA, Parkinson, J, Barlow, PN, Mullin, NP   +11 more
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