Results 41 to 50 of about 507,262 (350)

Our experience of coronary angiography with and without heparin

open access: yesIndian Heart Journal, 2012
Aim: Coronary angiography is usually done with heparin. Our aim is to see whether it can be done without heparin through femoral route and its effect on local complications.
Goutam Datta   +5 more
doaj   +1 more source

The Anticoagulant and Nonanticoagulant Properties of Heparin

open access: yesThrombosis and Haemostasis, 2020
Heparins represent one of the most frequently used pharmacotherapeutics. Discovered around 1926, routine clinical anticoagulant use of heparin was initiated only after the publication of several seminal papers in the early 1970s by the group of Kakkar ...
D. Beurskens   +5 more
semanticscholar   +1 more source

The importance of heparin and its derivatives in anticoagulant therapy and their new possible therapeutic uses [PDF]

open access: yes, 2023
This thesis provides a comprehensive review of the importance of heparin and its derivatives in anticoagulant therapy and their new possible therapeutic uses.
Ahmadi, Negar
core  

Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia

open access: yesNature Communications, 2019
Heparin-induced thrombocytopenia/thrombosis (HIT) is a serious immune reaction to heparins, characterized by thrombocytopenia and often severe thrombosis with high morbidity and mortality. HIT is mediated by IgG antibodies against heparin/platelet factor
J. Perdomo   +6 more
semanticscholar   +1 more source

A véralvadásgátló, heparin-analóg fondaparinux szintézisének lehetőségei [PDF]

open access: yes, 2021
A szervezetben a véralvadás egy igen fontos biokémiai folyamat akár külső sérülés, akár belső bakteriális hatás esetén is. A véralvadás kaszkád első lépésénél ható heparin és származékainak tulajdonsága, hogy negatív felületet biztosítanak az alvadás ...
Pap, Gergely
core  

Heparin-induced thrombocytopenia among patients of a comprehensive cancer center

open access: yesSAGE Open Medical Case Reports, 2014
Most clinical studies of heparin-induced thrombocytopenia have not included cancer patients who have high risk of thromboembolism, frequent exposure to heparin, and many potential causes of thrombocytopenia other than heparin-induced thrombocytopenia. To
Weixin Wu   +5 more
doaj   +1 more source

Living kidney transplantation without perioperative anticoagulation therapy for a patient with heparin‐induced thrombocytopenia

open access: yesIJU Case Reports, 2020
Introduction Heparin‐induced thrombocytopenia is an antibody‐mediated acquired prothrombotic state induced by heparin exposure. The risk of thromboembolic diseases in kidney transplantation with heparin‐induced thrombocytopenia without perioperative ...
Hayato Nishida   +9 more
doaj   +1 more source

Heparin-Coated Photosensitive MetalOrganic Frameworks as Drug Delivery Nanoplatforms of Autophagy Inhibitors for Sensitized Photodynamic Therapy against Breast Cancer [PDF]

open access: yes, 2021
Photosensitive nanosized metal–organic frameworks (nanoMOFs) with a tunable structure and high porosity have been developed recently as nanophotosensitizers (nanoPSs) for photodynamic therapy (PDT).
Mengmeng Zhang (1507543)   +15 more
core   +1 more source

Heparins: A Shift of Paradigm [PDF]

open access: yesFrontiers in Medicine, 2019
Heparins inhibit the thrombin forming capacity of plasma, i. e., the endogenous thrombin potential (ETP), by their anti-thrombin (aIIa) activity, the anti-factor Xa (aXa) activity is of minimal importance. This holds for both unfractionated heparin (UFH) and low molecular weight heparin (LMWH) at aXa/aIIa ratios < 25.
Hemker, H. Coenraad   +2 more
openaire   +4 more sources

Plasma free fatty acid levels influence Zn2+-dependent histidine-rich glycoprotein-heparin interactions via an allosteric switch on serum albumin [PDF]

open access: yes, 2014
Background: Histidine-rich glycoprotein (HRG) regulates coagulation, through its ability to bind and neutralize heparins. HRG associates with zinc ions (Zn2+) to stimulate HRG-heparin complex formation. Under normal conditions the majority of plasma Zn2+
Schwarz-Linek, Ulrich   +4 more
core   +1 more source

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