Results 21 to 30 of about 380,856 (149)

Graft-preserving intervention for treatment of heparin-induced thrombocytopenia secondary to a heparin-bonded renal artery bridging stent graft

Annals of Vascular Surgery - Brief Reports and Innovations, 2023
Heparin Induced Thrombocytopenia (HIT) is a well-recognized phenomenon in patients receiving heparin. Scoring systems such as the 4T score along with platelet factor 4 (PF4) testing have improved recognition and clinical improvement is typically observed
C.Y. Maximilian Png, John Schell, Alyssa M. Flores, Walter Dzik, Rebecca K. Leaf, Abhisekh Mohapatra   +5 more
doaj   +1 more source

Heparin release kinetics in blood gas syringes [PDF]

, 2008
Background: In view of the urgency of results quality and operational availability of point of care analyzers is of high importance in ICUs and operational theatres. Methods: We investigated the influence of time on release and total amount of Heparin in
Bechmann, Volker, Gruber, Michael, Spaeth, Ruth   +2 more
core   +1 more source

Heparin-Assisted Amyloidogenesis Uncovered through Molecular Dynamics Simulations

, 2022
Glycosaminoglycans (GAGs), in particular, heparan sulfate and heparin, are found colocalized with Aβ amyloid. They have been shown to enhance fibril formation, suggesting a possible pathological connection.
Alamzeb Khan (12441416), Jamshed Anwar (1988818), Abdul Wadood, Beenish Khurshid, Ashfaq Ur Rehman, Abdul Wadood (390961), Jamshed Anwar, Ray Luo (141237), Alamzeb Khan, Beenish Khurshid (12441413), Ray Luo, Ashfaq Ur Rehman (6117374)   +11 more
core   +1 more source

Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants

Frontiers in Molecular Biosciences, 2022
Heparan sulfate (HS) acts as a co-receptor of angiotensin-converting enzyme 2 (ACE2) by interacting with severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein (SGP) facilitating host cell entry of SARS-CoV-2 virus ...
Adrianne L. Gelbach, Fuming Zhang, Seok-Joon Kwon, John T. Bates, Andrew P. Farmer, Jonathan S. Dordick, Jonathan S. Dordick, Chunyu Wang, Chunyu Wang, Robert J. Linhardt, Robert J. Linhardt, Robert J. Linhardt   +11 more
doaj   +1 more source

Heparin-induced thrombocytopenia among patients of a comprehensive cancer center

SAGE Open Medical Case Reports, 2014
Most clinical studies of heparin-induced thrombocytopenia have not included cancer patients who have high risk of thromboembolism, frequent exposure to heparin, and many potential causes of thrombocytopenia other than heparin-induced thrombocytopenia. To
Weixin Wu, Kelly Merriman, Amr Nabaah, Nikhil Seval, Vahid Afshar-Kharghan, Sai-Ching J Yeung   +5 more
doaj   +1 more source

Living kidney transplantation without perioperative anticoagulation therapy for a patient with heparin‐induced thrombocytopenia

IJU Case Reports, 2020
Introduction Heparin‐induced thrombocytopenia is an antibody‐mediated acquired prothrombotic state induced by heparin exposure. The risk of thromboembolic diseases in kidney transplantation with heparin‐induced thrombocytopenia without perioperative ...
Hayato Nishida, Hiroki Fukuhara, Atsushi Yamagishi, Noriyuki Hosoya, Osamu Ichiyanagi, Toshihiko Sakurai, Sei Naito, Takuya Yamanobe, Tomoyuki Kato, Norihiko Tsuchiya   +9 more
doaj   +1 more source

A heparin-modified thermoresponsive surface with heparin-binding epidermal growth factor-like growth factor for maintaining hepatic functions in vitro and harvesting hepatocyte sheets

Regenerative Therapy, 2016
A heparin-modified thermoresponsive surface bound with heparin-binding epidermal growth factor-like growth factor (HB-EGF) was designed to allow creation of transferrable and functional hepatocyte sheets.
Yoshinori Arisaka, Jun Kobayashi, Kazuo Ohashi, Kohei Tatsumi, Kyungsook Kim, Yoshikatsu Akiyama, Masayuki Yamato, Teruo Okano   +7 more
doaj   +1 more source

Understanding heparin-induced thrombosis: A brief review

Medicina Universitaria, 2021
Heparin has been the first line for treatment and prevention of thrombosis for a while. However, one of its non-hemorrhagic effects remains noticeable: heparin-induced thrombocytopenia, mediated by antibodies directed to complexes of platelet factor, and
Mariela Irabien-Zúñiga, Edgar A. Rojas-Guerrero, David Gómez-Almaguer   +2 more
doaj   +1 more source

Plasma free fatty acid levels influence Zn2+-dependent histidine-rich glycoprotein-heparin interactions via an allosteric switch on serum albumin [PDF]

, 2014
Background: Histidine-rich glycoprotein (HRG) regulates coagulation, through its ability to bind and neutralize heparins. HRG associates with zinc ions (Zn2+) to stimulate HRG-heparin complex formation. Under normal conditions the majority of plasma Zn2+
Schwarz-Linek, Ulrich, Blindauer, Claudia A, Stewart, Alan J., Blindauer, Claudia A., Kassaar, Omar, Schwarz-Linek, Ulrich; id_orcid, Stewart, Alan J.; id_orcid   +6 more
core   +1 more source

Heparin Coating Technology in Cardiopulmonary Bypass

MATEC Web of Conferences, 2017
Heparin coating technology has become increasingly mature, which is conducive to the material of blood, biocompatibility proved very important, therefore, heparin coating technique has become a development cycle is very useful for in vitro selection of ...
Zhang Kun, Xue Rui, Shen Shuwei
doaj   +1 more source