Results 21 to 30 of about 374,140 (284)

Heparin-induced thrombocytopenia among patients of a comprehensive cancer center

open access: yesSAGE Open Medical Case Reports, 2014
Most clinical studies of heparin-induced thrombocytopenia have not included cancer patients who have high risk of thromboembolism, frequent exposure to heparin, and many potential causes of thrombocytopenia other than heparin-induced thrombocytopenia. To
Weixin Wu   +5 more
doaj   +1 more source

Heparins: A Shift of Paradigm [PDF]

open access: yesFrontiers in Medicine, 2019
Heparins inhibit the thrombin forming capacity of plasma, i. e., the endogenous thrombin potential (ETP), by their anti-thrombin (aIIa) activity, the anti-factor Xa (aXa) activity is of minimal importance. This holds for both unfractionated heparin (UFH) and low molecular weight heparin (LMWH) at aXa/aIIa ratios < 25.
Hemker, H. Coenraad   +2 more
openaire   +4 more sources

Living kidney transplantation without perioperative anticoagulation therapy for a patient with heparin‐induced thrombocytopenia

open access: yesIJU Case Reports, 2020
Introduction Heparin‐induced thrombocytopenia is an antibody‐mediated acquired prothrombotic state induced by heparin exposure. The risk of thromboembolic diseases in kidney transplantation with heparin‐induced thrombocytopenia without perioperative ...
Hayato Nishida   +9 more
doaj   +1 more source

Understanding heparin-induced thrombosis: A brief review

open access: yesMedicina Universitaria, 2021
Heparin has been the first line for treatment and prevention of thrombosis for a while. However, one of its non-hemorrhagic effects remains noticeable: heparin-induced thrombocytopenia, mediated by antibodies directed to complexes of platelet factor, and
Mariela Irabien-Zúñiga   +2 more
doaj   +1 more source

A heparin-modified thermoresponsive surface with heparin-binding epidermal growth factor-like growth factor for maintaining hepatic functions in vitro and harvesting hepatocyte sheets

open access: yesRegenerative Therapy, 2016
A heparin-modified thermoresponsive surface bound with heparin-binding epidermal growth factor-like growth factor (HB-EGF) was designed to allow creation of transferrable and functional hepatocyte sheets.
Yoshinori Arisaka   +7 more
doaj   +1 more source

Efficient Heparin Recovery from Porcine Intestinal Mucosa Using Zeolite Imidazolate Framework-8

open access: yesMolecules, 2022
Heparin is one of the most valuable active pharmaceutical ingredients, and it is generally isolated from porcine intestinal mucosa. Traditionally, different types of commercial resins are employed as an adsorbent for heparin uptake; however, using new ...
Mahmood Karimi Abdolmaleki   +4 more
doaj   +1 more source

The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids [PDF]

open access: yes, 2009
The ultraviolet circular dichroism (CD) spectra of commercial low-molecular-weight heparins, heparinoids and other anticoagulant preparations have been recorded between 180 and 260 nm.
Fernig, David G.   +7 more
core   +4 more sources

Heparin compared with normal saline to maintain patency of permanent double lumen hemodialysis catheters: A randomized controlled trial

open access: yesAdvanced Biomedical Research, 2014
Background: Heparin has long been used to prevent thrombosis in the permanent central venous hemodialysis catheters (PermCath). Other alternatives for heparin with fewer side-effects have recently been considered.
Ali Akbar Beigi   +3 more
doaj   +1 more source

Heparin-Assisted Amyloidogenesis Uncovered through Molecular Dynamics Simulations

open access: yes, 2022
Glycosaminoglycans (GAGs), in particular, heparan sulfate and heparin, are found colocalized with Aβ amyloid. They have been shown to enhance fibril formation, suggesting a possible pathological connection.
Alamzeb Khan (12441416)   +11 more
core   +1 more source

Heparin Coating Technology in Cardiopulmonary Bypass

open access: yesMATEC Web of Conferences, 2017
Heparin coating technology has become increasingly mature, which is conducive to the material of blood, biocompatibility proved very important, therefore, heparin coating technique has become a development cycle is very useful for in vitro selection of ...
Zhang Kun, Xue Rui, Shen Shuwei
doaj   +1 more source

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