Results 21 to 30 of about 524,934 (294)
Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]
, 2002 Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Belcher, P.R. +5 more
core +1 more source
Albumin-heparin microspheres as carriers for cytostatic agents [PDF]
, 1990 Much work has been done on adriamycin-loaded albumin microspheres (Alb-MS) for chemoembolization [1–4], the rationale being that site-specific drug delivery may increase the therapeutic efficacy of the drug. Alb-Ms are being investigated because of their
Bae, Y.H. +6 more
core +2 more sources
Heparin-Induced Thrombocytopenia [PDF]
New England Journal of Medicine, 1997 Heparin-induced thrombocytopenia (HIT), typically occurring in the second week of heparin therapy, is an antibody-mediated adverse drug reaction associated with increased thrombotic risk. The most important antigens are located on platelet factor 4 (PF4)/heparin complexes.
Naomi B, Klarenbeek +1 more
openaire +7 more sources
Preparation and characterization of albumin-heparin microspheres [PDF]
, 1994 Albumin-heparin microspheres were prepared by a two-step process which involved the preparation of a soluble albumin-heparin conjugate, followed by formation of microspheres from this conjugate or by a double cross-linking technique involving both ...
Bae, Y.H. +7 more
core +2 more sources
Heparin-induced thrombocytopenia among patients of a comprehensive cancer center
SAGE Open Medical Case Reports, 2014 Most clinical studies of heparin-induced thrombocytopenia have not included cancer patients who have high risk of thromboembolism, frequent exposure to heparin, and many potential causes of thrombocytopenia other than heparin-induced thrombocytopenia. To
Weixin Wu +5 more
doaj +1 more source
Heparin and air filters reduce embolic events caused by intra-arterial cerebral angiography - A prospective, randomized trial [PDF]
, 2004 Background-Intra-arterial cerebral angiography is associated with a low risk for neurological complications, but clinically silent ischemic events after angiography have been seen in a substantial number of patients.Methods and Results-In a prospective ...
Bartsch, AJ +8 more
core +1 more source
Evaluation of an Unfractioned Heparin Pharmacy Dosing Protocol for the Treatment of Venous Thromboembolism in Nonobese, Obese, and Severely Obese Patients [PDF]
, 2017 Background: Despite large interpatient variability in dose response, heparin is utilized for treatment of venous thromboembolism (VTE). Current data on the optimal heparin dosing in obese patients are conflicting. Objective: The objective was to evaluate
Breedlove, Emily Y. +3 more
core +2 more sources
IJU Case Reports, 2020 Introduction Heparin‐induced thrombocytopenia is an antibody‐mediated acquired prothrombotic state induced by heparin exposure. The risk of thromboembolic diseases in kidney transplantation with heparin‐induced thrombocytopenia without perioperative ...
Hayato Nishida +9 more
doaj +1 more source
Understanding heparin-induced thrombosis: A brief review
Medicina Universitaria, 2021 Heparin has been the first line for treatment and prevention of thrombosis for a while. However, one of its non-hemorrhagic effects remains noticeable: heparin-induced thrombocytopenia, mediated by antibodies directed to complexes of platelet factor, and
Mariela Irabien-Zúñiga +2 more
doaj +1 more source