Results 11 to 20 of about 507,262 (350)

The anti-cancer properties of heparin and its derivatives: a review and prospect

Cell Adhesion & Migration, 2020
Heparin, including unfractionated heparin (UFH), low-molecular-weight heparin (LMWH) and heparin derivatives, are commonly used in venous thromboembolism treatment and reportedly have beneficial effects on cancer survival.
Sai-Nan Ma, Zhi-Xiang Mao, Yang Wu, Ming-Xing Liang, Dan-Dan Wang, Xiu Chen, Ping-an Chang, Wei Zhang, Jin-Hai Tang   +8 more
doaj   +2 more sources

Life-threatening hemorrhage following subcutaneous heparin therapy [PDF]

Therapeutics and Clinical Risk Management, 2008
Jana Hudcova, Daniel TalmorDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USAAbstract: Prophylactic administration of unfractionated heparin is a common practice in ...
Jana Hudcova, Daniel Talmor
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Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial

British medical journal, 2021
Objective To evaluate the effects of therapeutic heparin compared with prophylactic heparin among moderately ill patients with covid-19 admitted to hospital wards. Design Randomised controlled, adaptive, open label clinical trial. Setting 28 hospitals in
M. Sholzberg, Grace H Tang, Hassan Rahhal, M. AlHamzah, L. B. Kreuziger, F. Áinle, F. Alomran, Khalid Alayed, M. Alsheef, Fahad AlSumait, C. E. Pompilio, C. Sperlich, S. Tangri, Terence Tang, Peter Jaksa, D. Suryanarayan, M. Almarshoodi, L. Castellucci, P. James, D. Lillicrap, M. Carrier, A. Beckett, C. Colovos, J. Jayakar, M. Arsenault, Cynthia Wu, K. Doyon, E. Andreou, Vera Dounaevskaia, E. Tseng, Gloria Lim, M. Fralick, S. Middeldorp, Agnes Y. Y. Lee, F. Zuo, Bruno R. da Costa, K. Thorpe, E. Negri, M. Cushman, P. Jüni, A. Laupacis, Yulia Lin, Andrew G. Day, B. Rochwerg, J. Abdulrehman, M. Gergi, R. Kondo, B. Piloto, Guilherme de Abreu Pereira, F. Valente, Ariel Fernando Villarroel Agreda, Pablo Andres Munoz Torres, Maíra Oliveira Moraes, Claudia de Lucena Moreira, Fernando Galassi Stocco Neto, Fabíola Vieira Duarte Baptista, J. A. Moreira, A. Ferreira, Paula Frudit, G. Martínez, H. Souza, R. A. B. Neto, E. D’Amico, E. Padrão, Fernando Sarin da Mota e Albuquerque, G. Zangrossi, A. K. Kanasiro, Alissom Vitti Cincoto, Hugo de Souza Reis, Vitor Miyashiro Arias da Silva, A. Bellintani, Vivian dos Santos Pereira, Yohana de Oliveira, B. J. Carvalho, Mariana de Souza Novaes, Henrique Brito Silveira, Gabriel César Alves de Avelar, Lara Bonanni Mota, K. Caciola, Matheus de Arêa Leão Freire Marim, Tales Cabral Monsalvarga, Alexandre Salgado Blanco Santos, A. Haydar, G. Saraiva, Sabrina Correa da Costa Ribeiro, Julio Flavio Meirelles Marchini, Júlio César Garcia de Alencar, Ana Catharina de Seixas Santos, Caroline Millette, M. Lebeau, C. Devaux, M. Boutin, T. N. Nguyen, L. Srour, Flávia De Angelis, Mariane Fugulin, A. Binnie, S. Bejaimal, A. Binding, Rosa M. Marticorena, G. Ginocchio, E. Kaplovitch, K. Rymaszewski, A. Raissi, Marcelo A. Falappa, B. Ernst, A. Ali, M. Romano, M. Khurram, Christie Kim, A. Kapur, Michelle L. Edwards, Vidushi Swarup, B. Camilotti, J. Jani, Jeff Carter, Mark R. Gillrie, Davinder Sidhu, Traci Robinson, Krystina Stutely, I. Watpool, R. Porteous, K. Jao, Jean-Samuel Boudreault-Pedneault, C. Kandel, Maureen Taylor, W. Choo, Laura Parsons, Ann Dowbenka, Gitana Ramonas, S. Nikitin, Jeffery M. Patterson, M. Hnatiuk, Anca Tapardel, S. T. Lapner, T. Carpenter, Lori Rackel, Rebecca M. Cairns, J. Pinder, P. Anglin, C. McPherson, Liselle Chiverton, David Barbosa, Shany Loukiantchenko, Y. Shamiss, D. Tassy, S. Shivakumar, Mary M. Keating, Susan Pleasance, B. Kevane, S. Cullivan, N. Power, P. Doran, K. Leamy, Aoife C Kelly, C. Moran, Mairead O’Connor, Aoife McDonnell, R. Boyce, Faiza Sefroun, R. Hussain, P. Murray, A. Malara, B. Molloy, M. O'Halloran, Emer Cunningham, J. Lambert, A. Cotter, B. Marsh, G. Sheehan, E. Muldoon, J. Woo, S. Gaine, Deirdre Morley, Farjah H Algahtani, I. Almaghlouth, Sondus I. Ata, Fai Alkhathlan, N. Khalil, Isra M. Hussein, Mohammed Bashir, Ahmed S. Bahammam, Abdulrahman Alsultan, H. Alkofide, T. Alhawassi, Abdulhadi M Alqahtani, E. Zayed, Ammar Alsughayir, Yacoub Abuzied, H. Alzahrani, Jawaher M Al-Otaibi, Haya S Alothaimeen, Noura Alzannan, Amer Al Homssi, H. Abid, S. Jones, S. Broaddrick, N. Jain, R. King, M. Jindal, Kristen M. Sanfilippo, Patricia Nieters, Muhammad Hammad, Aleeswa Francis Benny, T. Hamdan, Suhaib Kamal Ahmed Elobaid, Ibrahim Khafagi, S. S. Ahmed, AbduleRehman AlEssaie, Shamma Alalawi, Khloud Bashir, Aysha Abdulla Salem Al Suwaidi, H. I. Ahmed, M. Ismail, El Mutasim Ahmed El Faki, Mercy Charles, Alice Dang, Gurpreet Lakhanpal, Dominic Lee, Prachi Ray, M. Naydenova, K. Wysocki, Aziz Jiwajee, Greg Wendling, Rebekah H. Boyle, E. Cornell, D. K. Mukaz   +226 more
semanticscholar   +1 more source

Platelet factor 4 polyanion immune complexes: heparin induced thrombocytopenia and vaccine-induced immune thrombotic thrombocytopenia

Thrombosis Journal, 2021
Background This is a review article on heparin-induced thrombocytopenia, an adverse effect of heparin therapy, and vaccine-induced immune thrombotic thrombocytopenia, occurring in some patients administered certain coronavirus vaccines.
Payel Datta, Fuming Zhang, Jonathan S. Dordick, Robert J. Linhardt   +3 more
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Influence of different levels of heparin and antithrombin Ⅲ on human coagulation factor Ⅸ activity

Zhongguo shuxue zazhi, 2022
Objective To study the effect of different concentrations of heparin, ATⅢ or a mixture of heparin and antithrombin Ⅲ (ATⅢ) (1∶1)on the activity of human coagulation factor Ⅸ (FⅨ).
Changyong JIAN, Miaomiao DOU, chen CHEN, An ZHOU, Chao GAO, Cuiping ZHANG   +5 more
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The versatile heparin in COVID‐19

Journal of Thrombosis and Haemostasis, 2020
Coagulopathy in corona virus infection has been shown to be associated with high mortality with high D-dimers being a particularly important marker for the coagulopathy.1 In the latest paper from the same group, the use of anticoagulant therapy with ...
J. Thachil
semanticscholar   +1 more source

Heparin prevents caspase-11-dependent septic lethality independent of anticoagulant properties.

Immunity, 2021
Heparin, a mammalian polysaccharide, is a widely used anticoagulant medicine to treat thrombotic disorders. It is also known to improve outcomes in sepsis, a leading cause of mortality resulted from infection-induced immune dysfunction.
Yiting Tang, Xiangyu Wang, Zhaozheng Li, Zhihui He, Xinyu Yang, Xiaoye Cheng, Yue Peng, Qianqian Xue, Yang Bai, Rui Zhang, Kai Zhao, Fang Liang, Xianzhong Xiao, U. Andersson, Haichao Wang, T. Billiar, Ben Lu   +16 more
semanticscholar   +1 more source

Quantitative Analysis of Impurities in Unfractionated Heparin of Bovine Origin

Frontiers in Medicine, 2020
The USP heparin sodium monograph lists impurities with specifications developed for porcine derived products. Most of these impurities are of biological origin and are present in porcine intestinal mucosa, the tissue source used in the production of ...
Wesley E. Workman, Kevin L. Carrick
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Heparin-induced thrombocytopenia occurring early after living donor liver transplantation: a case report

Emergency and Critical Care Medicine, 2023
. Background. Thrombocytopenia commonly occurs early after liver transplantation. Heparin, usually administered as anticoagulant therapy for thrombosis, a common complication after liver transplantation, may cause heparin-induced thrombocytopenia ...
Naoya Iwasaki, Motohiro Sekino, Takanobu Hara, Akihiko Soyama, Masaaki Hidaka, Yusuke Kasai, Miki Suzumura, Hiroshi Araki, Rintaro Yano, Sojiro Matsumoto, Taiga Ichinomiya, Ushio Higashijima, Susumu Eguchi, Tetsuya Hara   +13 more
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Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions

Antiviral Research, 2020
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has resulted in a pandemic and continues to spread around the globe at an unprecedented rate.
S. Kim, Weihua Jin, Amika K. Sood, David W. Montgomery, Oliver C. Grant, M. Fuster, Li Fu, J. Dordick, R. Woods, Fuming Zhang, R. Linhardt   +10 more
semanticscholar   +1 more source