Results 11 to 20 of about 380,856 (149)

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

open access: yes, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S.   +3 more
core   +8 more sources

Life-threatening hemorrhage following subcutaneous heparin therapy

open access: yesTherapeutics and Clinical Risk Management, 2008
Jana Hudcova, Daniel TalmorDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USAAbstract: Prophylactic administration of unfractionated heparin is a common practice in ...
Jana Hudcova, Daniel Talmor
doaj   +1 more source

Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8 [PDF]

open access: yes, 2013
Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their ...
Gesteira, Tarsis F.   +11 more
core   +4 more sources

Serologic characterization of anti-protamine/heparin and anti-PF4/heparin antibodies

open access: yesBlood Advances, 2017
: Anti-protamine (PRT)/heparin antibodies are a newly described class of heparin-dependent antibodies occurring in patients exposed to PRT and heparin during cardiac surgery.
Grace M. Lee   +6 more
doaj   +1 more source

Heparin modification of a biomimetic bone matrix modulates osteogenic and angiogenic cell response in vitro [PDF]

open access: yesEuropean Cells & Materials, 2017
In this study, the effect of heparin-modified collagen type I/hydroxyapatite (HA) nanocomposites on key processes of bone regeneration – osteogenesis and angiogenesis – was characterised in vitro.
M Quade   +9 more
doaj   +1 more source

An Ovarian Cancer Patient Presenting Heparin - Induced Thrombocytopenia after use of Low - Molecular - Weight Heparin: A Case Report of Rare Condition

open access: yesGynecology Obstetrics & Reproductive Medicine, 2019
Heparin-induced thrombocytopenia is a rare and life-threatening condition of exposure to heparin. A case of heparin-induced thrombocytopenia due to the low molecular weight heparin was presented.
Yasin Durmuş   +8 more
doaj   +1 more source

Blended Heparin: A new Perspective to Guarantee the Supply of a Life-Saving Drug?

open access: yesClinical and Applied Thrombosis/Hemostasis, 2023
The risk of heparin shortage opens up the possibility of diversifying the sources of heparin by introducing products of other animal/organ origins. In addition to bovine heparin, already used in the past in the United States and Europe, ovine heparin can
Marco Guerrini MS
doaj   +1 more source

Heparin-induced thrombocytopenia: a rare presentation with skin necrosis

open access: yesDermatology Reports, 2023
Heparin-induced thrombocytopenia is the most clinically relevant non-haemorrhagic complication of heparin and is characterised by the presence of anti-PF4/heparin-IgG antibodies.
Filipa David   +3 more
doaj   +1 more source

Our experience of coronary angiography with and without heparin

open access: yesIndian Heart Journal, 2012
Aim: Coronary angiography is usually done with heparin. Our aim is to see whether it can be done without heparin through femoral route and its effect on local complications.
Goutam Datta   +5 more
doaj   +1 more source

Rivaroxaban Treatment for Heparin-Induced Thrombocytopenia: A Case Report and a Review of the Current Experience

open access: yesCase Reports in Hematology, 2020
Heparin-induced thrombocytopenia is a life-threatening complication of exposure to heparin. Heparin-induced thrombocytopenia results from an autoantibody directed against platelet factor 4 in complex with heparin.
Mohamed Aon, Omar Al-Shammari
doaj   +1 more source

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