Results 111 to 120 of about 482,727 (361)

The Comparative Study of Efficiency of Intravenous Heparin and Oral Aspirin on 48 Hours Beginning Primary Medication in Ischemic Stroke Patients

Journal of Rehabilitation, 2005
Objective: This study was done for comparing efficiency of Intravenous Heparin and Oral Aspirin among patients who had cerebral thrombi embolitic vascular accidents.
Ali Akbar Rezaei, Shahir Mazaheri, Saeed Bashirian, Nima Rezaei   +3 more
doaj  

Heparin-Activated Enzyme System of Human Plasma. [PDF]

, 1955
B. Shore
openalex   +1 more source

Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer.

New England Journal of Medicine, 2003
Agnes Y. Y. Lee, M. Levine, R. Baker, C. Bowden, A. Kakkar, M. Prins, F. Rickles, J. Julian, S. Haley, M. Kovacs, M. Gent   +10 more
semanticscholar   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

Activation of Lysosomal Retrograde Transport Triggers TPC1‐IP3R1 Ca2+ Crosstalk at Lysosome‐ER MCSs Leading to Lethal Depleting of ER Calcium

Advanced Science, EarlyView.
The flavonoid compound LW‐213 exerts its antitumor effects through a novel mechanism involving lysosomal‐ER calcium regulation. Specifically, LW‐213 binds to LIMP2, which induces perinuclear clustering of lysosomes and facilitates calcium‐mediated lysosome‐ER interactions.
Meng‐yuan Zhu, Yong‐jian Guo, Yu‐qi Zhu, Hong‐zheng Wang, Hai‐di Wang, Hong‐yu Chen, Yue‐xin Jiang, Hui Li, Hui Hui   +8 more
wiley   +1 more source

Dextran sulphate—a synthetic analogue of heparin [PDF]

, 1952
C. R. Ricketts
openalex   +1 more source

D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis

Advanced Science, EarlyView.
Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing, Jun Wu, Jingru Ning, Xiaoyu Ding, Zhenyun Du, Xiaojiang Wang, Lulin Huang, Ran Wang, Changlin Mei, Kan Ding   +9 more
wiley   +1 more source

Weak and Tunable Adhesion–Clutch Drives Rapid Cell Migration and Glioblastoma Invasion

Advanced Science, EarlyView.
This study proposes that adhesion–clutch can mediate both cell motility and immobilization depending on the force amplitude. Weak adhesion–clutch is well‐suited for cell migration, without forming strong adhesions that impede cell motility. It propels rapid dendritic cell migration controlled by extracellular chemicals, as well as pathologically ...
Kentarou Baba, Ami Fukushi‐Kumagai, Megumi Morisaki, Ryosuke Takeuchi, Zhize Xiao, Yoshikazu Nagashima, Mizuki Sakai, Yasuna Higashiguchi, Hiroko Katsuno‐Kambe, Asako Katsuma, Yoshihiro Ueda, Yuji Kamioka, Daisuke Kawauchi, Tatsuo Kinashi, Yonehiro Kanemura, Naoyuki Inagaki   +15 more
wiley   +1 more source

Comparison of aPTT and CT Parameter of the ROTEM Test to Monitor Heparin Anti-Coagulation Effect in ICU Patients: an Observational Study

Acta Medica Iranica, 2015
Heparin is frequently used in different clinical settings to reduce the coagulating ability of the blood. Because of probable adverse effects owing to heparin therapy and regarding variability of patients’ responses to heparin, which make it very ...
Atabak Najafi, Masoomeh Nikeish, Farhad Etezadi, Pejman Pourfakhr, Farsad Imani, Mohammad Reza Khajavi, Reza Shariat Moharari   +6 more
doaj  

Biomedical applications of engineered heparin-based materials

Bioactive Materials
Heparin is a negatively charged polysaccharide with various chain lengths and a hydrophilic backbone. Due to its fascinating chemical and physical properties, nontoxicity, biocompatibility, and biodegradability, heparin has been extensively used in ...
Ehsan Nazarzadeh Zare, Danial Khorsandi, Atefeh Zarepour, Hulya Yilmaz, Tarun Agarwal, Sara Hooshmand, Reza Mohammadinejad, Fatma Ozdemir, Onur Sahin, Sevin Adiguzel, Haroon Khan, Ali Zarrabi, Esmaeel Sharifi, Arun Kumar, Ebrahim Mostafavi, Negar Hosseinzadeh Kouchehbaghi, Virgilio Mattoli, Feng Zhang, Vadim Jucaud, Alireza Hassani Najafabadi, Ali Khademhosseini   +20 more
doaj   +1 more source