Results 241 to 250 of about 507,262 (350)

Protamine dosing in cardiac surgery: method is key. [PDF]

J Thorac Dis
Beukers AM, Mansvelder FJ, Eberl S, Hermanns H.   +3 more
europepmc   +1 more source

Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors.

Journal of Clinical Investigation, 1990
J. Weitz, M. Hudoba, D. Massel, J. Maraganore, J. Hirsh   +4 more
semanticscholar   +1 more source

Calcified Plaque Detachment: Alternative Calcified Plaque Modification After Coronary Intravascular Lithotripsy

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Calcified plaque (CP) detachment (CD) and calcium fracture (CF) can occur following coronary intravascular lithotripsy (IVL). The extent to which CF alone facilitates stent expansion during CP modification with IVL remains unclear. Aims This study aimed to investigate the clinical implications of IVL‐induced CD.
Daisuke Naito, Akiko Matsuo, Takeru Kasahara, Keisuke Ota, Shinsaku Matsunaga, Norio Nakajima   +5 more
wiley   +1 more source

Ticagrelor-Induced False-Negative Serotonin Release Assay in Heparin-Induced Thrombocytopenia With Stent Thrombosis. [PDF]

JACC Case Rep
Jamil Y, Bahniwal RK, Nguyen AH, Howard E, Azad F, Ershler WB, Kennedy JLW.   +6 more
europepmc   +1 more source

A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis.

New England Journal of Medicine, 1996
M. Levine, M. Gent, J. Hirsh, J. Leclerc, D. Anderson, J. Weitz, Jeffrey S. Ginsberg, A. Turpie, C. Demers, M. Kovacs   +9 more
semanticscholar   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Case report: Heparin coagulant super-sensitivity during leech therapy. [PDF]

Thromb J
Rong Z, Daniels A, Luu K, Czerwonka L, Bahou WF.   +4 more
europepmc   +1 more source

Unfractionated heparin versus bivalirudin in primary percutaneous coronary intervention (HEAT-PPCI): an open-label, single centre, randomised controlled trial.

The Lancet, 2014
A. Shahzad, I. Kemp, Christine Mars, Keith Wilson, Claire Roome, R. Cooper, M. Andron, C. Appleby, M. Fisher, A. Khand, B. Kunadian, J. Mills, J. Morris, W. Morrison, S. Munir, N. Palmer, R. Perry, D. Ramsdale, P. Velavan, R. Stables   +19 more
semanticscholar   +1 more source

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response—A Randomized, Placebo‐Controlled Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse, Aliede E. in 't Veld, Hendrika W. Grievink, Manon A.A. Jansen, Matthijs Moerland   +4 more
wiley   +1 more source

Heparin-Coated Tunneled Hemodialysis Catheters Improve Failure-Free Survival in ESRD. [PDF]

Medicina (Kaunas)
Tasci V, Tekin AF, Tanrıkulu YE, Özer İ, Taydas O, Ozdemir M, Topaloglu OF, Islam M, Öztürk MH.   +8 more
europepmc   +1 more source