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Heparin Mimetics

2011
Explorations of the therapeutic potential of heparin mimetics, anionic compounds that are analogues of glycosaminoglycans (GAGs), have gone hand-in-hand with the emergence of understanding as to the role of GAGs in many essential biological processes.
Coombe, Deidre, Kett, W.
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Heparin Biosynthesis

2011
Heparin and heparan sulfate share the same polysaccharide backbone structure but differ in sulfation degree and expression pattern. Whereas heparan sulfate is found in virtually all cells of the human body, heparin expression is restricted to mast cells, where it has a function in storage of granular components such as histamine and mast cell specific ...
Pernilla, Carlsson, Lena, Kjellén
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Heparin Structure

Pathophysiology of Haemostasis and Thrombosis, 1990
Heparins used in therapy are largely constituted by sequences of the trisulfated disaccharide <i>L</i>-iduronic acid-2-sulfate→<i>D</i>-glucosamine-N,6-disulfate. These regular sequences are interrupted by undersulfated (occasionally, oversulfated) sequences containing <i>D</i>-glucuronic acid and N-acetylated <i ...
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Heparin

New England Journal of Medicine, 1991
John A. Oates   +2 more
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Heparin

MCN, The American Journal of Maternal/Child Nursing, 1985
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Heparin

Clinics in Haematology, 1981
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Heparin

New England Journal of Medicine, 1968
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