Results 251 to 260 of about 564,053 (333)

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

Advanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim, Si Hyeon Chae, Dahae Lee, Bum Soo Lee, Jiseok Lim, Hyo‐Il Jung, Ki Hyun Kim, Bongseop Kwak   +7 more
wiley   +1 more source

Anticoagulant regimens for different therapeutic plasma exchange modes. [PDF]

Front Med (Lausanne)
Yao R, Huang H, Ming Y, Guo H, Miao L, Wang S, Wan J, Zhou J, Wang X, Wu Y, Yuan Y, Wang T, Li R.   +12 more
europepmc   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

Timing of Anticoagulation Resumption in a Patient With Mechanical Heart Valves and Spontaneous Subdural Hematomas: A Case Report. [PDF]

Cureus
Baby S, Lozonschi L.
europepmc   +1 more source

Investigations on the Chemistry of Heparin

, 1962
I. Danishefsky, Harold B. Eiber, Esther Langholtz   +2 more
openalex   +1 more source

Biodegradable Medical Implants: Reshaping Future Medical Practice

Advanced Science, EarlyView.
Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia, Yan Liu, Yangkun Xing, Zhewei Shi, Xiaocheng Pang   +4 more
wiley   +1 more source

Improving the safety of heparin usage by standardisation of practice. [PDF]

BMJ Open Qual
Lui PL, Tan SC, Goh PW, Mohankumar B, Tun Ye PM, Tin KC, Yap ES, Teo WZY.   +7 more
europepmc   +1 more source

Effect of Heparin on the Decrease in Blood Coagulation Factor Activity Associated with Experimental Endotoxemia

, 1967
R. Lee West, PAUL B. JENNINCS, ROBERRT M. HARDAWAY, ERIC A. LUNDBERG   +3 more
openalex   +2 more sources

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Reprogramming FGF1 from the natural growth factor to the engineered heparan sulphate biosensor. [PDF]

Cell Commun Signal
Ciura K, Sobota O, Chorążewska A, Krowarsch D, Porębska N, Opaliński Ł.   +5 more
europepmc   +1 more source