Results 21 to 30 of about 41,263 (236)
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Varied application of intercostal trans-diaphragmatic ports for laparoscopic hepatectomy.
PLoS ONE, 2020 BackgroundThe ribcage and diaphragm are mechanical barriers for laparoscopic access during hepatectomy. Here, we introduce the varied application of intercostal trans-diaphragmatic ports during laparoscopic hepatectomy, and describe the management of ...
Hiromitsu Hayashi +9 more
doaj +1 more source
Outcomes of surgery for giant hepatic hemangioma
BMC Surgery, 2021 Background The surgical indications for liver hemangioma remain unclear. Methods Data from 152 patients with hepatic hemangioma who underwent hepatectomy between 2004 and 2019 were retrospectively reviewed.
Qing-song Xie +5 more
doaj +1 more source
Cancer Medicine, 2017 Up to three‐quarters of patients undergoing liver resection for colorectal liver metastases (CRLM) develop intrahepatic recurrence. Repeat hepatic resection appears to provide the optimal chance of cure for these patients.
Christopher P. Neal +7 more
doaj +1 more source
Appropriate indications for laparoscopic repeat hepatectomy
BMC Surgery, 2023 Background Laparoscopic repeat hepatectomy (LRH) has increased, but appropriate indications for LRH are unclear. This study aimed to clarify appropriate indications for LRH. Methods We retrospectively compared surgical outcomes between open RH (ORH) (n =
Takashi Masuda +9 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundThe purpose of this study was to compare the efficacy and safety of transarterial chemoembolization (TACE) in combination with radiofrequency ablation (RFA) (TACE-RFA) and repeat hepatectomy in the treatment of recurrent hepatocellular ...
Xin Zheng +5 more
doaj +1 more source
European Journal of Medical Research, 2023 Background Patients with malignant tumors are more likely to have psychological problems due to their worries about their life expectancy. To understand the psychological status of elderly patients with malignant liver tumor undergoing hepatectomy better,
Lining Xu +3 more
doaj +1 more source
Partial hepatectomy in mice [PDF]
Laboratory Animals, 2015 The surgical procedure of two-thirds partial hepatectomy (PH) in rodents was first described more than 80 years ago by Higgins and Anderson. Nevertheless, this technique is still a state-of-the-art method for the community of liver researchers as it allows the in-depth analysis of signalling pathways involved in liver regeneration and ...
Y A, Nevzorova +3 more
openaire +2 more sources
Liver Transplantation, EarlyView., 2022 Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono +8 more
wiley +1 more source