ABSTRACT Hepatocellular carcinoma (HCC) surveillance with semi‐annual ultrasound (US) is recommended for high‐risk patients. This study investigates the impact of hepatobiliary abbreviated magnetic resonance imaging (AMRI) performed annually on the recommended US surveillance.
Jing‐Houng Wang +4 more
wiley +1 more source
Sedative-like effect of intraperitoneal GABA administration in the open field test [PDF]
Gamma-Amino Butyric Acid (GABA) is the main inhibitor neurotransmitter of the Central Nervous System (CNS). Its peripheral administration has been matter of discussion. On the one hand, it has been reported that it does not cross the Blood-Brain Barrier (
Gargiulo, Augusto Pascual Ítalo +7 more
core +1 more source
Affinities and densities of high-affinity [3H]muscimol (GABA-A) binding sites and of central benzodiazepine receptors are unchanged in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy [PDF]
Roger F. Butterworth +3 more
openalex +1 more source
ABSTRACT Sepsis‐associated liver injury (SALI) plays a major role in aggravating disease progression and worsening prognosis in patients with sepsis. Macrophage polarization is a key factor in the modulation of SALI progression. Recent studies have shown that human breast milk‐derived exosomes (HBM‐Exos) regulate processes involved in macrophage ...
Zhao‐Bin Yang +3 more
wiley +1 more source
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
core +2 more sources
18‐FDG PET in the Evaluation of Therapeutic Response of Necrotizing Otitis Externa
PET performed well in assessing the therapeutic response of NEO, with excellent sensitivity but low specificity of visual analysis. A complementary quantitative analysis was useful to distinguish between satisfactory and insufficient partial responses. ABSTRACT Objective The duration of antibiotic treatment for necrotizing otitis externa (NEO) and the ...
Lucie Lécolier +5 more
wiley +1 more source
Non-absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic encephalopathy in people with cirrhosis [PDF]
Background Non-absorbable disaccharides (lactulose and lactitol) are recommended as first-line treatment for hepatic encephalopathy. The previous (second) version of this review included 10 randomised clinical trials (RCTs) evaluating non-absorbable ...
Gluud, LL, Morgan, MY, Vilstrup, H
core
PWE-153 Cost Effectiveness Of Rifaximin-a In The Reduction Of Recurrence Of Overt Hepatic Encephalopathy [PDF]
CD Poole +5 more
openalex +1 more source
Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang +13 more
wiley +1 more source

