Results 121 to 130 of about 678,448 (346)

Physiologically-Based Pharmacokinetic Modeling of Blood Clearance of Liver Fluorescent Markers for the Assessment of the Degree of Hepatic Ischemia-Reperfusion Injury [PDF]

arXiv, 2023
During liver transplantation, ischemia-reperfusion injury (IRI) is inevitable and decreases the overall success of the surgery. While guidelines exist, there is no reliable way to quantitatively assess the degree of IRI present in the liver. Our recent study has shown a correlation between the bile-to-plasma ratio of FDA-approved sodium fluorescein (SF)
arxiv  

Delineation of monocytic and early‐stage myeloid‐derived suppressor cells in the peripheral blood of patients with hepatocarcinoma

International Journal of Cancer, Volume 156, Issue 12, Page 2416-2428, 15 June 2025.
What's new? In hepatocellular carcinoma, expanded myeloid‐derived suppressor cells (MDSC) relate to aggressiveness and poor prognosis. A global analysis of the different MDSC subsets in hepatocellular carcinoma is, however, missing. In this study, all three subsets of M‐MDSC, PMN‐MDSC, and eMDSC, together with arginase 1 activity, were significantly ...
Marta Chivite‐Lacaba, Iago Justo, Alberto Utrero‐Rico, Oscar Caso, Cecilia González‐Cuadrado, Manuel J. Del Rey, Rocio Laguna‐Goya, Javier Arroyo‐Ródenas, Ángel Alfocea‐Molina, Carlota C. Ruigómez‐Martín, Manuel Serrano, Lorena Pascual‐Palacios, María Esther Mancebo, Estela Paz‐Artal   +13 more
wiley   +1 more source

Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients

Alimentary Pharmacology and Therapeutics, 2018
Minimal hepatic encephalopathy (HE) and HE grade 1 (HE1) according to the West Haven criteria have recently been grouped as one entity named—covert HE‐ (CHE).
C. Labenz, J. Baron, G. Toenges, J. Schattenberg, Michael Nagel, M. Sprinzl, M. Nguyen-Tat, Tim Zimmermann, Y. Huber, J. Marquardt, P. Galle, M. Wörns   +11 more
semanticscholar   +1 more source

Aszites, Pfortaderthrombose und hepatische Enzephalopathie bei Leberzirrhose: Aktuelle Therapieempfehlungen [PDF]

, 2012
Treatment of Ascites, Portal Vein Thrombosis and Hepatic Encephalopathy in Patients with Cirrhosis of the Liver Background: Ascites, portal vein thrombosis and hepatic encephalopathy are important complications of cirrhosis of the liver.
Abecasis R, Acosta S, Alexander L. Gerbes, Als-Nielsen B, Als-Nielsen B, Amitrano L, Amitrano L, Amitrano L, Arroyo V, Bajaj JS, Bellot B, Bismuth M, Córdoba J, D'Avola D, de Franchis V, DeLeve LD, Fiaccadori F, Francoz C, Francoz C, Gerbes AL, Gerbes AL, Gerbes AL, Gines P, Gluud LL, Gülberg V, Han G, Häussinger D, Luca A, Montagnese S, Prasad S, Rajani R, Rivkin A, Rosemurgy AS, Rossle M, Rössle M, Salerno F, Salerno F, Salerno F, Sanyal AJ, Senzolo M, Tarantino G, Tublin ME, Veit Gülberg, Wong F, Wong F, Zillikens MC, Zocco MA   +46 more
core   +1 more source

Melatonin Levels in Serum and Ascitic Fluid of Patients with Hepatic Encephalopathy

Gastroenterology Research and Practice, 2012
Cirrhotic patients exhibit disturbed melatonin homeostasis, which may lead to sleep disturbances, but an influence on the hepatic encephalopathy has not been elucidated. Aim.
Cezary Chojnacki, Marek Romanowski, Katarzyna Winczyk, Janusz Błasiak, Jan Chojnacki   +4 more
doaj   +1 more source

Grading the severity of hypoxic-ischemic encephalopathy in newborn EEG using a convolutional neural network [PDF]

arXiv, 2020
Electroencephalography (EEG) is a valuable clinical tool for grading injury caused by lack of blood and oxygen to the brain during birth. This study presents a novel end-to-end architecture, using a deep convolutional neural network, that learns hierarchical representations within raw EEG data.
arxiv  

Patient‐derived tumor organoids highlight the potential of precision medicine in managing pancreatic ductal adenocarcinoma

International Journal of Cancer, EarlyView.
What's New? Only about one‐fifth of patients with pancreatic ductal adenocarcinoma (PDAC) qualify for curative treatment approaches employing adjuvant chemotherapy. Tools to predict PDAC response to chemotherapeutic regimens, however, are lacking.
Christine Nitschke, Charline Phan, Yara Souto, Philipp Walter, Mara Goetz, Gediminas Simkus, Jacob Thastrup, Ronald Simon, Jürgen Kupper, Jakob Izbicki, Steven A. Johnsen, Thilo Hackert, Marianne Sinn, Harriet Wikman, Faik G. Uzunoglu, Tabea M. Sturmheit   +15 more
wiley   +1 more source

The burden of minimal hepatic encephalopathy: from diagnosis to therapeutic strategies

Annals of gastroenterology : quarterly publication of the Hellenic Society of Gastroenterology, 2018
Minimal hepatic encephalopathy (MHE) is the mildest form of hepatic encephalopathy (HE). It affects the performance of psychometric tests focused on attention, working memory, psychomotor speed, and visuospatial ability, as well as electrophysiological ...
L. Ridola, V. Cardinale, O. Riggio
semanticscholar   +1 more source

Symptom Domain Groups of the Patient-Reported Outcomes Measurement Information System Tools Independently Predict Hospitalizations and Re-hospitalizations in Cirrhosis [PDF]

, 2017
Background Patient-Reported Outcomes Measurement Information System (PROMIS) tools can identify health-related quality of life (HRQOL) domains that could differentially affect disease progression.
Bajaj, Jasmohan S., Fagan, Andrew, Fuchs, Michael, Gavis, Edith A., Luketic, Velimir A., Matherly, Scott, Patidar, Kavish R., Puri, Puneet, Sanyal, Arun J., Siddiqui, Mohammad S., Sterling, Richard K., Stravitz, Richard T., Thacker, Leroy R., Wade, James B., White, Melanie B.   +14 more
core   +2 more sources

Evaluating the ability of fullPIERS calculator to predict adverse maternal outcomes in pre‐eclampsia at Charlotte Maxeke Johannesburg Academic Hospital

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the ability of the fullPIERS model to predict adverse maternal outcomes in patients diagnosed as early‐onset pre‐eclampsia at Charlotte Maxeke Johannesburg Academic Hospital, South Africa. Methods Retrospective record review and analysis of 134 patients admitted with early‐onset pre‐eclampsia.
Thomas Matonhodze, Robert Nyakoe
wiley   +1 more source