Results 121 to 130 of about 83,984 (282)

Amino Acid Imbalance Is an Independent Factor for Mortality in Patients With Liver Cirrhosis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Amino acid imbalance, reflected by a low branched‐chain amino acids (BCAA)‐to‐tyrosine ratio (BTR), independently predicts mortality in patients with cirrhosis. Both decreased serum BCAA and increased tyrosine levels are significant and independent prognostic markers.
Yuki Utakata   +10 more
wiley   +1 more source

Problems in Treating Experimentally Induced Acute Hepatic Failure by Hemoperfusion or Cross Circulation [PDF]

open access: yes, 1983
Acute hepatic failure was induced in rats by galactosamine injection intraperitoneally (1 gm per kg). Twenty-four hours later rats were treated by hemoperfusion (HP) over encapsulated sorbents: cellulose acetate-coated charcoal, polyelectrolyte-coated ...
Beyerbacht, Ellen C.   +3 more
core   +2 more sources

Altered Pathogen Spectrum of Spontaneous Bacterial Peritonitis in Patients Treated With Proton Pump Inhibitors

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This multicenter, observational study reveals distinct alterations in the microbial spectrum of spontaneous bacterial peritonitis (SBP) associated with proton pump inhibitor use. These results are especially relevant for guiding empiric antibiotic therapy of SBP.
Philip Kitchen   +13 more
wiley   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo   +13 more
wiley   +1 more source

Sarcopenia Is Associated With Mortality and Progression of Cirrhosis in Decompensated but Not Compensated Disease—A Multicentre Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective cohort of 1,624 adults with cirrhosis, sarcopenia was independently associated with unplanned hospitalization, death, and cirrhosis progression (or death) in patients with decompensated disease. In compensated cirrhosis, sarcopenia was associated only with a higher risk of unplanned hospitalization.
Puneeta Tandon   +12 more
wiley   +1 more source

First Latin American consensus on the treatment and prophylaxis of hepatic encephalopathy

open access: yesAnnals of Hepatology
Introduction and Objectives: Hepatic encephalopathy (HE) is a frequent and severe complication of cirrhosis, leading to rapid deterioration and increased mortality.
Fátima Higuera-de-la-Tijera   +14 more
doaj   +1 more source

The effects of portacaval shunt upon hepatic cholesterol synthesis and cyclic AMP in dogs and baboons [PDF]

open access: yes, 1980
Hepatic cholesterol synthesis, hepatic cyclic AMP, and portal and peripheral insulin and glucagon levels were investigated in nine dogs and three baboons after complete portacaval shunt.
Benichou, J   +3 more
core  

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

open access: yesCell Proliferation, EarlyView.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang   +10 more
wiley   +1 more source

Hepatic Encephalopathy

open access: yesSouth African Medical Journal, 2018
Click on the link to view the editorial.
Eric Kallwitz, Zurabi Lominadze
openaire   +3 more sources

Current Trends in the Epidemiology of Obesity and the Association Between Obesity and Metabolic Liver Disease (MASLD/MASH)

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Excess adiposity and obesity are increasingly prevalent, with incidence rising in many parts of the world; both trigger a state of metabo‐inflammation in adipose tissue, creating a systemic milieu characterised by insulin resistance and pro‐inflammatory and fibrogenic states. Along with systemic inflammatory cues, perturbations in systemic and
Mirjana Grocic   +2 more
wiley   +1 more source

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