M S, Losowsky, B B, Scott
openaire +4 more sources
Classification of Hepatic Lesions using the Matching Metric [PDF]
In this paper we present a methodology of classifying hepatic (liver) lesions using multidimensional persistent homology, the matching metric (also called the bottleneck distance), and a support vector machine. We present our classification results on a dataset of 132 lesions that have been outlined and annotated by radiologists.
arxiv
Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez+8 more
wiley +1 more source
Severe hepatitis in pediatric patients: The Severe Hepatitis In Pediatric Patients (SHIPP) registry
Abstract Objectives Clusters of severe acute hepatitis in children were reported worldwide beginning in October 2021. Although most children recovered, some progressed to liver failure leading to death or liver transplantation. Herein, we characterize the clinical characteristics, and outcomes of this group of children through an international ...
Mohit Kehar+31 more
wiley +1 more source
Branched-chain amino acids for people with hepatic encephalopathy.
BACKGROUND Hepatic encephalopathy is a brain dysfunction with neurological and psychiatric changes associated with liver insufficiency or portal-systemic shunting. The severity ranges from minor symptoms to coma. A Cochrane systematic review including 11
L. Gluud+6 more
semanticscholar +1 more source
Trends in Characteristics, Mortality, and Other Outcomes of Patients With Newly Diagnosed Cirrhosis [PDF]
Importance: Changes in the characteristics of patients with cirrhosis are likely to affect future outcomes and are important to understand in planning for the care of this population.
Chalasani, Naga+6 more
core +1 more source
Quality of life in patients with minimal hepatic encephalopathy
Minimal hepatic encephalopathy (MHE) represents the mildest type of hepatic encephalopathy (HE). This condition alters the performance of psychometric tests by impairing attention, working memory, psychomotor speed, and visuospatial ability, as well as ...
L. Ridola+3 more
semanticscholar +1 more source
Modification in CSF specific gravity in acutely decompensated cirrhosis and acute on chronic liver failure independent of encephalopathy, evidences for an early blood-CSF barrier dysfunction in cirrhosis [PDF]
Although hepatic encephalopathy (HE) on the background of acute on chronic liver failure (ACLF) is associated with high mortality rates, it is unknown whether this is due to increased blood-brain barrier permeability.
Agarwal, B+7 more
core +1 more source
Diagnosis of Minimal Hepatic Encephalopathy Using Neuropsychometric Tests
Hepatic encephalopathy is threatening complication of both acute and chronic liver failure. Minimal hepatic encephalopathy is the initial stage of encephalopathy, has no neurological symptoms with the manifestation of cognitive impairment, and therefore ...
V.B. Yahmur+2 more
doaj +1 more source
Abstract Objective The authors' objective with this narrative review is to explore the impact of rehabilitative interventions at each stage of liver disease. Type Narrative review. Literature Survey Literature search conducted in Medline, Embase, and Google Scholar databases.
Laura Malmut+5 more
wiley +1 more source