Results 81 to 90 of about 31,185 (231)

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

Animal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang, Wei Li, Weiwen Zheng, Jinwen Liu, Nuonan She, Xia Chen, Weibo Wen   +6 more
wiley   +1 more source

Hepatic Encephalopathy: A Review

European Medical Journal Hepatology, 2021
Hepatic encephalopathy (HE) is a reversible syndrome observed in patients with liver disease. The syndrome is characterised by a spectrum of neuropsychiatric abnormalities resulting from the accumulation of neurotoxic substances in the bloodstream and ...
Savan Kabaria, Ishita Dalal, Kapil Gupta, Abhishek Bhurwal, Minacapelli Carlos D., Carolyn Catalano, Vinod Rustgi   +6 more
doaj   +1 more source

Mathematical model of immune response to hepatitis B [PDF]

J. Theor. Biol. 447, 98-110 (2018), 2018
A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady states is performed to identify parameter regions where the model exhibits clearance of infection, maintenance of a ...
arxiv   +1 more source

Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]

, 1999
In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Hammer, C., Heil, W., Lemmens, H.-P., Matthes, M., Neuhaus, P., Padval, D., Puhl, G., Schön, M. R.   +7 more
core   +1 more source

Therapeutic efficacy of l-ornithine l-aspartate in patients with hepatic encephalopathy [PDF]

, 2015
To determine the efficacy of ornithine-aspartate in reducing blood ammonia levels and clinical improvement, as a part of treatment in hepatic encephalopathy. Material & method: A randomized placebo controlled trial was conducted in 2013 in Jinnah medical
Aidrus, Fadieleh, Ghaur, M. Ishaq, Kumar, Ajeet, Razzaque, Salma, Siddiqui, Afshan   +4 more
core   +1 more source

Brain edema : a valid endpoint for measuring hepatic encephalopathy? [PDF]

, 2016
Hepatic encephalopathy (HE) is a major complication of liver failure/disease which frequently develops during the progression of end-stage liver disease.
Bémeur, Chantal, Cooper, Arthur J. L., Cudalbu, Cristina, Dam, Gitte, Rose, Christopher, Thrane, Alexander S.   +5 more
core   +1 more source

Systematic review: the role of frailty in advanced chronic liver disease

Alimentary Pharmacology &Therapeutics, Volume 57, Issue 3, Page 280-289, February 2023., 2023
The role of frailty indices in advanced chronic liver disease. Summary Background Frailty is a known predictor of outcome and mortality in patients undergoing liver transplantation. However, most patients remain unsuitable transplant candidates. It is not yet known if the assessment of frailty in non‐transplant candidates can aid prognostication.
Sarah P. Bowers, Paul N. Brennan, John F. Dillon   +2 more
wiley   +1 more source

Stochastic Modelling Approach to the Incubation Time of Prionic Diseases [PDF]

, 2003
Transmissible spongiform encephalopathies like the bovine spongiform encephalopathy (BSE) and the Creutzfeldt-Jakob disease (CJD) in humans are neurodegenerative diseases for which prions are the attributed pathogenic agents. A widely accepted theory assumes that prion replication is due to a direct interaction between the pathologic (PrPsc) form and ...
arxiv   +1 more source

Improved quality of life in patients with refractory or recidivant ascites after insertion of transjugular intrahepatic portosystemic shunts [PDF]

, 2002
Background. We have recently shown that the transjugular intrahepatic portosystemic shunt (TIPS) is more effective than paracentesis in the treatment of cirrhotic patients with severe ascites and can prolong survival in selected patients.
Bilzer, M., Gerbes, Alexander L., Gülberg, Veit, Liss, I., Reiser, Maximilian F., Waggershauser, T.   +5 more
core   +1 more source