Results 141 to 150 of about 102,559 (263)

A post hoc analysis of linaclotide in pediatric patients with functional constipation and neurodevelopmental disorders

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Functional constipation (FC) is common in children with comorbid neurodevelopmental disorders (NDD) and its optimal treatment may be challenged by adherence and medication tolerability issues in this population. We assessed the efficacy and safety of linaclotide in pediatric patients with FC and NDD.
Hannibal Person, Jeffrey S. Hyams, Rinarani M. Sanghavi, Valentina Shakhnovich, Katherine Kosch, Moming Li, Danielle D'Achino, Julie Khlevner, Bruno P. Chumpitazi, Miguel Saps   +9 more
wiley   +1 more source

Platelets accelerate endoplasmic reticulum stress and promote hepatic steatosis. [PDF]

JHEP Rep
Derler M, Dube T, Ableitner E, Schrottmaier WC, Salzmann M, Kolb D, De Campos AM, Engelke H, Annerer E, Kunowska N, Schmid J, Beck S, Nieswandt B, Assinger A, Stelzl U, Mussbacher M.   +15 more
europepmc   +1 more source

The utility of whole exome sequencing in diagnosing Wilson disease: A case report

JPGN Reports, EarlyView.
Abstract Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by mutations in the ATP7B gene, resulting in toxic copper accumulation in the body. Diagnosis is typically based on biochemistries, including low serum ceruloplasmin and elevated 24‐h urine copper excretion, with Kayser–Fleischer (KF) rings being a supportive ...
Mihir J. Palan, Dana Simpson, Cheryl Miranda, Melanie Hakar, Henry C. Lin   +4 more
wiley   +1 more source

Renal Denervation Improves Hepatic Steatosis in Hypertensive Patients With Metabolic Syndrome. [PDF]

Hypertension
Tokcan M, Hohl M, Schneider CV, Schneider KM, Markwirth P, Bernhard B, Haring B, Lauder L, Schattenberg J, Mahfoud F, Kulenthiran S, Böhm M.   +11 more
europepmc   +1 more source

Impact of cystic fibrosis transmembrane conductance regulator modulator therapies on liver stiffness and liver enzymes: An observational perspective single‐center cohort study

JPGN Reports, EarlyView.
Abstract Objectives The efficacy of cystic fibrosis transmembrane conductance regulator (CFTR)‐modulator therapies in preventing or ameliorating cystic fibrosis liver disease (CFLD) by correcting CFTR in cholangiocytes is not well‐documented. This study aimed to assess liver function during CFTR‐modulators.
Laura Giugliano, Elisabetta Augustoni, Antonio Pizzol, Anna Opramolla, Cristina Chiadò, Anna Zagaria, Irene Esposito, Giulia Roberto, Alice Ponte, Andrea Evangelista, Paola Quarello, Michele Pinon, Pier Luigi Calvo   +12 more
wiley   +1 more source

Impact of Elovl3 Suppression on Sleep Deprivation-Induced Hepatic Steatosis and Glucose Intolerance in Mice. [PDF]

Cureus
Shigiyama F, Tanaka S, Okayama C, Kumashiro N.   +3 more
europepmc   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Clinical Utility of the Triglyceride-Glucose Index in Assessing Hepatic Steatosis Severity Within the MASLD Spectrum. [PDF]

Diagnostics (Basel)
Alakuş ÖF, Solmaz İ, Kiliç J, Çiçek S.   +3 more
europepmc   +1 more source

Impact of Cardiometabolic Risk Factors and Steatotic Liver Disease on Liver‐Related Outcomes in Patients With Chronic Hepatitis C After Curative Antiviral Therapy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Patients with chronic hepatitis C (CHC) frequently present with steatotic liver disease (SLD) and cardiometabolic risk factors (CMRFs). This study aimed to evaluate the impact of SLD and CMRFs on liver‐related outcomes (LROs) in CHC patients after HCV eradication.
Chung‐Feng Huang, Yi‐Hung Lin, Pei‐Chien Tsai, Ming‐Lun Yeh, Chih‐Wen Wang, Tyng‐Yuan Jang, Po‐Cheng Liang, Yu‐Ju Wei, Nai‐Jen Hou, Ming‐Yen Hsieh, Chao‐Kuan Huang, Tzu‐Chun Lin, Jee‐Fu Huang, Chia‐Yen Dai, Wan‐Long Chuang, Ming‐Lung Yu   +15 more
wiley   +1 more source

The relationship between acromegaly and hepatic steatosis: insights from FibroScan imaging. [PDF]

J Endocrinol Invest
Apaydin T, Kani HT, Keklikkiran C, Yilmaz Y, Yavuz DG.   +4 more
europepmc   +1 more source