Results 121 to 130 of about 164,357 (279)

Infliximab-induced autoimmune-like hepatitis in a patient with Crohn’s disease: a case report

Future Science OA
As medical treatments advance, drug-induced liver injury (DILI) becomes more prevalent, occurring at a rate of 14 to 19 cases per 100,000 individuals. We present a unique case of a female patient with Crohn’s disease developing autoimmune-like hepatitis ...
Shema Ayadi, Salma Merhaben, Linda Hadj Kacem, Soumaya Rammeh, Asma Mensi, Emna Belhadj Mabrouk, Yosra Zaimi, Leila Mouelhi   +7 more
doaj   +1 more source

Secondary Hemophagocytic Lymphohistiocytosis: A Challenging Diagnosis in a Patient with Autoimmune Hepatitis

Case Reports in Critical Care, 2019
Background. We describe a case of secondary Hemophagocytic Lymphohistiocytosis (HLH) from autoimmune hepatitis mimicking severe sepsis in a man admitted to the intensive care unit. Case Presentation.
Colin Casault, Juan G. Posadas-Calleja
doaj   +1 more source

Oncologic Emergencies: Immune-Based Cancer Therapies and Complications [PDF]

, 2020
Cancer therapies have undergone several recent advancements. Current cancer treatments include immune-based therapies comprised of checkpoint inhibitors, and adoptive immunotherapy; each treatment has the potential for complications that differ from ...
Brém, Elizabeth, Koyfman, Alex, Long, Brit Jeffrey   +2 more
core  

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, EarlyView.
What's New? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source

Immunology Highlights of Four Major Idiosyncratic DILI Subtypes Verified by the RUCAM: A New Evidence-Based Classification

Livers
Conventionally, drug-induced liver injury (DILI) exists in two types: idiosyncratic and intrinsic. Both types are classified as non-immune disorders, thereby ignoring that some iDILI cases may have an immune or autoimmune background that requires a ...
Rolf Teschke
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Smoking is a Risk Factor for Autoimmune Hepatitis: An English Registry-Based Case–Control Study

Clinical Epidemiology
Lisbet Grønbæk,1– 3 Harmony Omeife,3 Lu Ban,4 Colin J Crooks,5 Timothy R Card,3,4 Peter Jepsen,1,3 Joe West3,4,6 1Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; 2Department of Medicine, Regional Hospital ...
Grønbæk L, Omeife H, Ban L, Crooks CJ, Card TR, Jepsen P, West J   +6 more
doaj  

Quantitative Mapping of Fibrotic Tissue Mechanics via Brillouin Spectroscopy

Journal of Biophotonics, EarlyView.
Brillouin spectroscopy distinguishes fibrotic from healthy tissue based on localized stiffness changes and enables real‐time monitoring of dynamic alterations in viscoelastic properties during fibrogenesis. ABSTRACT Fibrosis is a pathological scarring process that disrupts tissue architecture, and is characterized by excessive extracellular matrix (ECM)
Vsevolod Cheburkanov, Sujeong Jung, Mikhail Y. Berezin, Vladislav V. Yakovlev   +3 more
wiley   +1 more source

Reference Intervals for Lymphocyte Subpopulations in Healthy Chinese Han Adults: A Single‐Center Study

Journal of Clinical Laboratory Analysis, EarlyView.
Correlation matrix analysis of lymphocyte parameters. The correlation matrix showed the positive (red) or negative (blue) correlation of two parameters; the color intensity reflected the correlation coefficient. Conducting lymphocyte testing in health management can help monitor immune status, evaluate health risks, analyze pathogenesis of diseases ...
An‐Na Jiang, Lin‐Zi Miao, Yan Gong, Ran You, Yao Lu, Chen‐Xue Qu   +5 more
wiley   +1 more source

Case report: liver failure as a debut of autoimmune hepatitis triggered by dengue virus in a pregnant woman

Revista Peruana de Medicina Experimental y Salud Pública
Autoimmune hepatitis (AIH) is a complex condition with unclear origins, involving genetic susceptibility and environmental triggers that lead to immune system dysfunction.
Karina Sato-Espinoza, Diego Berrospi, Javier Diaz-Ferrer   +2 more
doaj   +1 more source