Results 151 to 160 of about 57,133 (184)

Assessment of central blood volume in cirrhosis by radionuclide angiography [PDF]

, 1994
Bendtsen, Flemming, Blendis, Laurence, Gerbes, Alexander L., Henriksen, Jens H., Møgelvang, Jens, Møller, Søren, Peter Liu, Liu, Ring-Larsen, Helmer, Stokholm, K. Heine, Sørensen, Thorkild I. A., Wong, Florence   +10 more
core  

Prevalence and Predictors of Suspected Metabolic Dysfunction‐Associated Steatotic Liver Disease in Adolescents in the United States

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 9, Page 1479-1488, May 2025.
This study determined the prevalence of suspected MASLD among U.S. adolescents using NHANES 2011–2020 data, finding that 14.6% had elevated ALT, of whom 77.2% met MASLD criteria. Elevated BMI, dyslipidemia, and high blood pressure were key predictors, highlighting the importance of screening for cardiometabolic risk factors in this population. ABSTRACT
Sheila L. Noon, Lauren F. Chun, Tin Bo Nicholas Lam, Nhat Quang N. Thai, Winston Dunn, Jeffrey B. Schwimmer   +5 more
wiley   +1 more source

Comparison Between Dynamic Models for Predicting Response to Corticosteroids in Alcohol‐Associated Hepatitis: A Global Cohort Study

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 8, Page 1391-1395, April 2025.
This multinational cohort study compared dynamic scores for predicting corticosteroid response and mortality in severe alcohol‐associated hepatitis. The Lille‐7 score demonstrated the highest accuracy for 30‐ to 90‐day mortality, while the Lille‐4 and TSB models were also effective. In contrast, Delta NLR lacked predictive utility.
Francisco Idalsoaga, Luis Antonio Díaz, Leonardo Guizzetti, Winston Dunn, Heer Mehta, Jorge Arnold, Gustavo Ayares, Rokhsana Mortuza, Gurpreet Mahli, Alvi H. Islam, Shiv K. Sarin, Rakhi Maiwall, Wei Zhang, Steve Qian, Douglas Simonetto, Ashwani K. Singal, Mohamed A. Elfeki, Carolina Ramirez‐Cadiz, Joaquín Cabezas, Victor Echavarría, Meritxell Ventura Cots, María Fátima Higuera‐De La Tijera, Juan G. Abraldes, Mustafa Al‐Karaghouli, Prasun K. Jalal, Mohamad Ali Ibrahim, Guadalupe García‐Tsao, Daniela Goyes, Lubomir Skladaný, Daniel J. Havaj, Karolina Sulejova, Svetlana Adamcova Selcanova, Diego Rincón, Vijay H. Shah, Patrick S. Kamath, Marco Arrese, Ramon Bataller, Juan Pablo Arab   +37 more
wiley   +1 more source

Patient Reported Outcomes in Primary Sclerosing Cholangitis: An Australian Perspective

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 10, Page 1612-1621, May 2025.
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) is a rare, cholestatic liver condition that has a significant association with inflammatory bowel disease (IBD) and impaired health‐related quality of life (HRQOL). We aimed to characterise and compare validated PSC and IBD patient‐reported outcomes (PRO) and determine if PRO correlated ...
Natassia Tan, Christopher Zampogna, Kate Lynch, Nicholas Hannah, Siddharth Sood, Kate Collins, Avik Majumdar, Andrew Coulshed, Ken Liu, Rohit Sawhney, Stephen Bloom, John Lubel, William Kemp, Stuart Roberts, Ammar Majeed, Amanda J. Nicoll   +15 more
wiley   +1 more source

Extracellular Vesicles miRNome Profiling Reveals miRNAs Engagement in Dysfunctional Lipid Metabolism, Chronic Inflammation and Liver Damage in Subjects With Metabolic Dysfunction‐Associated Steatotic Liver Disease

Alimentary Pharmacology &Therapeutics, EarlyView.
This study explores the association between the miRNome profile of circulating extracellular vesicles and metabolic dysfunction, liver inflammation, and damage in patients with metabolic MASLD, identifying key miRNAs (miR‐122‐5p, miR‐375‐3p, let‐7d‐5p, and let‐7f‐5p) that modulate lipid metabolism and inflammatory pathways in ‘at‐risk MASH’ patients ...
Gian Paolo Caviglia, Elisabetta Casalone, Chiara Rosso, Serena Aneli, Alessandra Allione, Fabrizia Carli, Cristina Grange, Angelo Armandi, Chiara Catalano, Giovanni Birolo, Beatrice Foglia, Davide Giuseppe Ribaldone, Amalia Gastaldelli, Giuseppe Matullo, Elisabetta Bugianesi   +14 more
wiley   +1 more source

Diabetes Mellitus in Patients With Autoimmune Hepatitis: Frequency, Risk Factors and Effect on Outcome

Alimentary Pharmacology &Therapeutics, EarlyView.
New‐onset DM occurred in 13% of patients with AIH, was related to older age, non‐Caucasian ethnicity, higher prednisolone dose, higher BMI at diagnosis and weight gain and was an independent predictor of all‐cause death/transplantation and of cirrhosis development, underlining the need to minimise steroid burden in AIH.
Sarah Flatley, Selena Dixon, Eleanor Pilsworth, Asha Dube, Barbara Hoeroldt, Laura Harrison, Dermot Gleeson   +6 more
wiley   +1 more source

Alterations in Gut Microbiota Composition Are Related to Disease Severity and Systemic Inflammation in Patients With Chronic Urticaria

Allergy, EarlyView.
Han‐Ki Park, Young Her, Doo Young Choi, Tansol Park, Jae‐Woo Kwon   +4 more
wiley   +1 more source

Origins of T‐cell‐mediated autoimmunity in acquired aplastic anaemia

British Journal of Haematology, Volume 206, Issue 4, Page 1035-1053, April 2025.
Acquired aplastic anaemia (AA) is an autoimmune bone marrow failure disease caused by a cytotoxic T‐cell–mediated attack on haematopoietic stem and progenitor cells (HSPCs). Despite significant progress in understanding T‐cell repertoire alterations in AA, the identification of specific pathogenic T cells remains elusive.
Aura Enache, Shannon A. Carty, Daria V. Babushok   +2 more
wiley   +1 more source

Anti‐PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT‐like and VITT‐like characteristics

British Journal of Haematology, EarlyView.
Summary Vaccine‐induced immune thrombocytopenia and thrombosis (VITT) is one of several anti‐platelet factor 4 (anti‐PF4)‐associated immune thrombocytopenia and thrombosis (PITT) syndromes. As well as following adenoviral vector vaccines, VITT has recently been described following acute adenovirus infection.
Phillip L. R. Nicolson, Samantha J. Montague, Richard J. Buka, Anthony Calvert, Jo‐Ann I. Sheppard, Yi Zhang, Jing Jing Wang, Jack Sharman, Eman Hassan, James Harrison, Errin Lawrence, Phillip El‐Dalil, Dhruv Parekh, Husam Osman, Tom P. Gordon, Ishac Nazy, Theodore E. Warkentin, Will A. Lester   +17 more
wiley   +1 more source

Atezolizumab, obinutuzumab and venetoclax for the treatment of patients with relapsed/refractory B non‐Hodgkin lymphoma: Final analysis of a phase II trial from the LYSA group

British Journal of Haematology, EarlyView.
Summary Developing new therapeutic regimens for relapsed/refractory (R/R) B non‐Hodgkin lymphoma (NHL) patients remains a significant unmet clinical need. Our objective was to evaluate atezolizumab (ATE), obinutuzumab (OBI) and venetoclax (VEN) combination in patients with R/R NHL who had received at least one prior anti‐CD20‐containing ...
Charles Herbaux, Emmanuel Bachy, Reda Bouabdallah, Stéphanie Guidez, Olivier Casasnovas, Pierre Feugier, Gandhi Damaj, Hervé Tilly, Loïc Ysebaert, Steven Le Gouill, Nadine Morineau, Emmanuel Gyan, Rémy Gressin, Roch Houot, Morgane Cheminant, Franck Morschhauser, Catherine Thieblemont, Corinne Haioun, Emmanuelle Nicolas‐Virelizier, Luc‐Matthieu Fornecker, Nicolas Daguindau, Guillaume Cartron   +21 more
wiley   +1 more source