Results 171 to 180 of about 57,133 (184)
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Seminars in Immunopathology, 2009
Autoimmune hepatitis (AIH) is an inflammatory liver disease affecting mainly females and characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by the presence of autoantibodies and increased levels of immunoglobulin G.
Diego, Vergani +4 more
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Autoimmune hepatitis (AIH) is an inflammatory liver disease affecting mainly females and characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by the presence of autoantibodies and increased levels of immunoglobulin G.
Diego, Vergani +4 more
openaire +4 more sources
Surgical Pathology Clinics, 2013
Autoimmune hepatitis is a chronic necroinflammatory disease of unknown etiology that is characterized by increased aminotransferases, serum autoantibodies, increased immunoglobulin G levels, and histological interface hepatitis. The disease does not have a pathognomonic clinical, laboratory, or histological feature; diagnosis depends on a combination ...
Cristina D, Cole, Romil, Saxena
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Autoimmune hepatitis is a chronic necroinflammatory disease of unknown etiology that is characterized by increased aminotransferases, serum autoantibodies, increased immunoglobulin G levels, and histological interface hepatitis. The disease does not have a pathognomonic clinical, laboratory, or histological feature; diagnosis depends on a combination ...
Cristina D, Cole, Romil, Saxena
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The Indian Journal of Pediatrics, 2001
Autoimmune hepatitis is one of the causes of chronic progressive liver disease in childhood. Here we report 14 cases with clinical findings, therapeutic management and prognosis, in order to define the course of the disease. Diagnosis of autoimmune hepatitis was done with the presence of at least one of these autoantibodies; antinuclear antibody ...
Inci Nur Saltik +4 more
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Autoimmune hepatitis is one of the causes of chronic progressive liver disease in childhood. Here we report 14 cases with clinical findings, therapeutic management and prognosis, in order to define the course of the disease. Diagnosis of autoimmune hepatitis was done with the presence of at least one of these autoantibodies; antinuclear antibody ...
Inci Nur Saltik +4 more
openaire +3 more sources
Nature Reviews Disease Primers, 2018
Autoimmune hepatitis (AIH) is a severe liver disease that affects children and adults worldwide. The diagnosis of AIH relies on increased serum transaminase and immunoglobulin G levels, presence of autoantibodies and interface hepatitis on liver histology.
Giorgina, Mieli-Vergani +7 more
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Autoimmune hepatitis (AIH) is a severe liver disease that affects children and adults worldwide. The diagnosis of AIH relies on increased serum transaminase and immunoglobulin G levels, presence of autoantibodies and interface hepatitis on liver histology.
Giorgina, Mieli-Vergani +7 more
openaire +4 more sources
Clinics in Liver Disease, 2002
This chapter describes perturbations in the signaling, apoptotic, and regulatory pathways within the innate and adaptive immune systems that favor the development of autoimmune hepatitis. Molecular mimicry, neoantigens, epitope spread, and promiscuous targeting by activated lymphocytes are discussed, and the genetic predispositions implicated in the ...
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This chapter describes perturbations in the signaling, apoptotic, and regulatory pathways within the innate and adaptive immune systems that favor the development of autoimmune hepatitis. Molecular mimicry, neoantigens, epitope spread, and promiscuous targeting by activated lymphocytes are discussed, and the genetic predispositions implicated in the ...
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Orvosi Hetilap, 2007
First the short history of the disease, then its etiopathogenesis, the role of genetic, environmental and immunologic factors are described. In the second part, the questions of diagnosis, differential diagnosis and the immunosuppressive treatment, with new therapeutic modalities and liver transplantation are discussed.
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First the short history of the disease, then its etiopathogenesis, the role of genetic, environmental and immunologic factors are described. In the second part, the questions of diagnosis, differential diagnosis and the immunosuppressive treatment, with new therapeutic modalities and liver transplantation are discussed.
openaire +5 more sources
The Indian Journal of Pediatrics, 1995
Autoimmune hepatitis can present as either acute or chronic disease in children. Clinical and laboratory features, including association with extrahepatic autoimmune syndromes and prompt response to immunosuppressive treatment, circulating autoantibodies and hypergammaglobulinemia, suggest an immune etiology.
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Autoimmune hepatitis can present as either acute or chronic disease in children. Clinical and laboratory features, including association with extrahepatic autoimmune syndromes and prompt response to immunosuppressive treatment, circulating autoantibodies and hypergammaglobulinemia, suggest an immune etiology.
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Autoantibodies in Autoimmune Hepatitis
Digestive Diseases, 2015<b><i>Background:</i></b> The detection of diagnostic autoantibodies such as antinuclear antibodies (ANA), anti-smooth muscle antibodies (SMA), anti-liver/kidney microsomal type 1 (anti-LKM1), anti-liver cytosol type 1 (anti-LC1) and anti-soluble liver antigen (anti-SLA) is historically associated with the diagnosis of ...
MURATORI, LUIGI +8 more
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2010
Case History—A 24 yr old woman presenting with a short history of jaundice. Autoimmune hepatitis describes chronic inflammation in the liver attributed to immune responses against self-antigens in the liver, typically in the form of a marked portal tract infiltrate containing both plasma cells and T cells.
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Case History—A 24 yr old woman presenting with a short history of jaundice. Autoimmune hepatitis describes chronic inflammation in the liver attributed to immune responses against self-antigens in the liver, typically in the form of a marked portal tract infiltrate containing both plasma cells and T cells.
openaire +1 more source