Results 81 to 90 of about 164,357 (279)
Pediatrics and Neonatology, 2009 Untreated autoimmune hepatitis (AIH) can develop into liver cirrhosis, with potentially fatal outcomes. Viral hepatitis in children was endemic in Taiwan before universal hepatitis B vaccination, but AIH has rarely been reported in Taiwanese children. We
Sheng-Hsiung Yeh +5 more
doaj +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Risk Factors For Multiple Sclerosis In Volyn Region (Ukraine) [PDF]
, 2016 The prevalence rate of multiple sclerosis (MS) in Volyn Region (101.0 per 100000) is the highest in Ukraine. To study MS risk factors in Volyn Region, special questionnaires were distributed among all MS patients residing in Volyn region.
Bobryk, N. (Nataliia) +1 more
core +2 more sources
Autoimmune hepatitis: Histopathology [PDF]
Clinical Liver Disease, 2014 Watch a video presentation of this article Figure 1.
openaire +2 more sources
Annals of Gastroenterological Surgery, EarlyView.ROC analyses of APRI score, EOB‐MRI, and a combination of EOB‐MRI and APRI score for blue liver. ABSTRACT Aim Sinusoidal obstruction syndrome (SOS), also known as “blue liver (BL),” is a common hepatic injury following oxaliplatin‐based chemotherapy in patients with colorectal liver metastases (CRLM).
Tomonari Shimagaki +7 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT The therapeutic landscape of hepatocellular carcinoma (HCC) has been transformed by recent advancements in systemic therapies, particularly with the introduction of immune checkpoint inhibitors, expanding treatment options beyond conventional locoregional approaches.
Keiichi Akahoshi +4 more
wiley +1 more source
Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]
, 2005 CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Bertoletti, A. +6 more
core +2 more sources
مجله دانشکده پزشکی اصفهان, 2017 Background: Chronic hepatitis is a common disease in the community. Differential diagnosis of hepatitis is very important in the treatment of this disease; as applying the wrong treatment method can lead to reinforcement and aggravate.
Mohammadhossein Sanei +3 more
doaj
Stem cell therapies for autoimmune hepatitis
Stem Cell Research & Therapy, 2021 Autoimmune hepatitis is a chronic inflammatory hepatic disorder which may cause liver fibrosis. Appropriate treatment of autoimmune hepatitis is therefore important.
Ahmed Lotfy +6 more
doaj +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou +6 more
wiley +1 more source