Results 191 to 200 of about 484,484 (318)

Oral paltusotine, a nonpeptide selective somatostatin receptor 2 agonist: Mass balance, absolute bioavailability and metabolism in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo   +6 more
wiley   +1 more source

Recent advances of nanomaterials in imaging liver fibrosis

open access: yesBMEMat, EarlyView.
Schematic summary on the latest strategies of liver fibrosis imaging based on various nanomaterials. Abstract Liver fibrosis is a pathological process resulting from prolonged exposure to various injury factors. It is characterized by the abnormal proliferation and activation of hepatic stellate cells and excessive deposition of extracellular matrix ...
Jin Cui   +11 more
wiley   +1 more source

Chronic active and chronic inactive hepatitis B virus infection: Comparative study of genetic polymorphism and blood profile measures. [PDF]

open access: yesPLoS One
Awadelkarim KE   +10 more
europepmc   +1 more source

Liver organoids: From 3D printing to biomedical applications

open access: yesBMEMat, EarlyView.
A comprehensive review on liver organoids culture techniques from 3D printing to organ‐on‐chip, as well as focusing on challenges and perspectives for advancement liver organoids in various future applications. Abstract The liver is an immune organ, especially an immune tolerance organ.
Ying Shi   +4 more
wiley   +1 more source

Pareto in Prison

open access: yesBehavioral Sciences &the Law, EarlyView.
ABSTRACT The Pareto principle is based on the concept that roughly 80% of outcomes are generated by 20% of inputs, efforts, or contributors within a group. Using a national sample of U.S. prison inmates, we examined various percentile rankings of self‐reported institutional misconduct to determine how much disorder is created behind bars by the most ...
Mark A. Morgan   +3 more
wiley   +1 more source

Hepatitis B associated with severe COVID-19: a nationwide cohort study in Sweden. [PDF]

open access: yesVirol J
Jakobsson F   +6 more
europepmc   +1 more source

Towards the elimination of Viral Hepatitis in Clinton County, New York [PDF]

open access: yes
Chronic viral hepatitis is a major public health issue, affecting approximately 300 million persons globally. In Clinton County, New York, chronic viral hepatitis remains a major concern, with incidence rates for hepatitis C virus infection (HCV) in the ...
Le, Michael H.
core   +1 more source

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